Outcomes of Kidney Transplantation After Primary, Repeat and Kidney After Nonrenal Solid Organ Transplantation: 10 Years UNOS Database Analysis.
1Division of Nephrology, University of Kentucky, Lexington, KY
2Division of Cardiology, University of Kentucky, Lexington, KY
3Division of Transplant Surgery, University of Kentucky, Lexington, KY
Meeting: 2017 American Transplant Congress
Abstract number: 519
Keywords: Graft failure, Graft survival, Retransplantation, Survival
Session Information
Session Name: Concurrent Session: Kidney General Outcomes
Session Type: Concurrent Session
Date: Tuesday, May 2, 2017
Session Time: 4:30pm-6:00pm
Presentation Time: 5:06pm-5:18pm
Location: E354a
Introduction: The aim of the study is to evaluate patient and kidney allograft survivals in primary, repeat, and kidney after nonrenal organ transplantation using national data reported to United Network for Organ Sharing (UNOS).
Patients and Methods: We retrospectively studied adult patients who received kidney transplants between January 2000 and December 2014. Given the inherent instability of comparing a small subgroup with a very large subgroup, a 10% cohort of primary kidney transplants was randomly selected from UNOS database and used as a comparison group. We excluded patients who received kidney and other solid organ transplant simultaneously and patients with more than 2 organ transplants. Survival time for each patient was stratified into the following groups[mdash]group A (comparison group): recipients of primary kidney transplant (21,076 patients), group B: recipients of repeat kidney transplant (4,428 patients), and group C: recipients of kidney transplants performed after a previous non renal transplant (liver, heart, and lung) (1,558 patients). We compared survivals using Kaplan-Meier curves.
Results: The median graft survival time of the kidney transplants was 11.3 years for group A, 11.0 years in group B and 8.1 years for group C (P < 0.001). The 1, 5, and 10 years graft survival was 94%, 78% and 55% in group A, 92%, 74% and 55% in group B, and 92%, 68% and 40% in group C, respectively. The 1, 5, and 10 years patient survival was 97%, 85% and 63% in group A, 97%, 86% and 64% in group B, and 93%, 71% and 42% in group C, respectively. Graft and patient survivals in group C were significantly lower than group A and B (P < 0.001 for both) [Figure 1 and 2].
Conclusion: Compared to primary or repeat kidney transplant, the kidney and patient survivals are significantly lower in patients with kidney transplant after non renal solid organ transplant.
CITATION INFORMATION: Ramirez J, Aghil H, Baz M, Sawaya B, Rajagopalan N, Mei X, Gedaly R, El-Husseini A. Outcomes of Kidney Transplantation After Primary, Repeat and Kidney After Nonrenal Solid Organ Transplantation: 10 Years UNOS Database Analysis. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Ramirez J, Aghil H, Baz M, Sawaya B, Rajagopalan N, Mei X, Gedaly R, El-Husseini A. Outcomes of Kidney Transplantation After Primary, Repeat and Kidney After Nonrenal Solid Organ Transplantation: 10 Years UNOS Database Analysis. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/outcomes-of-kidney-transplantation-after-primary-repeat-and-kidney-after-nonrenal-solid-organ-transplantation-10-years-unos-database-analysis/. Accessed May 13, 2025.« Back to 2017 American Transplant Congress