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Outcome of Liver Transplantation in Patients with Prior Bariatric Surgery.

M. Safwan,1 M. Abouljoud,1 R. Salgia.2

1Divison of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
2Gastroenterology, Henry Ford Hospital, Detroit, MI

Meeting: 2017 American Transplant Congress

Abstract number: B204

Keywords: Liver transplantation, Metabolic disease, Post-operative complications

Session Information

Session Name: Poster Session B: Liver Retransplantation and Other Complications

Session Type: Poster Session

Date: Sunday, April 30, 2017

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall D1

Aim: To study outcomes of liver transplantation (LT) patients with prior bariatric surgery (BS).

Methods: Retrospective analysis performed on patients with LT between Jan 2006 and Dec 2015, to identify those with prior BS. Simultaneous liver-kidney transplantation (SLK) & multi-visceral transplantation (MVT) patients included.

Results: 960 patients underwent LT; 12 (1.3%) had prior BS. Median follow-up was 31.5 months. Most common BS was Roux-en-y gastric bypass (n=10). Median interval between BS and LT was 9 years. Nine patients underwent LT alone, 2 SLK and 1 MVT. Most common indication for LT was NASH (n=10) with 5 (42%) having concurrent alcoholic liver disease. Median MELD was 28. Median length-of-stay was 9 days. 30-day re-operation rate was 33% (n=4); indications were bile duct repair (n=3) and wound repair (n=1). In first 6 months after LT, most common complications were biliary strictures/leaks (n=6) and abdominal collections (n=3). Patient and graft survival rates at 1 and 2 years were 92% (n=11) and 83% (n=10). Eight patients (67%) had indications for liver biopsy post-LT; two (17%) showed macrovesicular steatosis. In patients with history of alcohol consumption, 2 (40%) relapsed post-LT. Two patients (17%) had history of diet-controlled diabetes pre-LT; one became insulin dependent post-LT. Median BMI pre-LT was 29.6. Median BMI at 1, 6, and 12 months post-LT was 26.9, 28.6, and 32.7. Median preoperative albumin was 2.4 mg/dl. Patients showed improvement in albumin post LT, with median albumin of 2.4 and 3.3 mg/dl, at 1 and 3 months. Liver profile stable post LT, with median AST of 30 and 22 IU/L and ALT of 21 and 28 IU/L, at 6 and 12 months.

Conclusions: Outcomes of LT patients with prior BS are comparable to other transplant recipients with regards to patient and graft survival, and post-LT complication rates.

CITATION INFORMATION: Safwan M, Abouljoud M, Salgia R. Outcome of Liver Transplantation in Patients with Prior Bariatric Surgery. Am J Transplant. 2017;17 (suppl 3).

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To cite this abstract in AMA style:

Safwan M, Abouljoud M, Salgia R. Outcome of Liver Transplantation in Patients with Prior Bariatric Surgery. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/outcome-of-liver-transplantation-in-patients-with-prior-bariatric-surgery/. Accessed May 13, 2025.

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