Long-Term Social Outcome after Pediatric Kidney Transplantation

Y. Hamasaki,¹ T. Matsuda,¹ M. Kubota,¹ J. Hashimoto,¹ Y. Takahashi,¹ M. Muramatsu,² T. Kawamura,³ K. Sakai,² S. Shishido.^1,2

¹Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan
²Nephrology, Toho University Faculty of Medicine, Tokyo, Japan
³Nephrology, Sakura Medical Center, Toho University, Sakura, Japan.

Meeting: 2018 American Transplant Congress

Abstract number: B244

Keywords: Graft survival, Pregnancy, Prognosis, Quality of life

Session Information

Session Name: Poster Session B: Kidney: Pediatrics

Session Type: Poster Session

Date: Sunday, June 3, 2018

Session Time: 6:00pm-7:00pm

Presentation Time: 6:00pm-7:00pm

Location: Hall 4EF

Background

Patients' and graft survival rates after pediatric kidney transplantation (KTx) were recently improved because of progress in immunosuppressants, perioperative care, and operative procedures. Therefore the quality of life and social outcome after the KTx were regarded as important and started gaining attention.

Methods

The patients who underwent KTx under 18 years old and spent over 10 years follow-up were included in this study. The average age at first KTx was 9.3±4.5 years, with 56 males and 50 females. The average age at last follow-up was 29.7±8.9 years, and follow-up periods after first KTx was 20.4±7.0 years. We evaluated the several points of the patients, including primary disease, kidney, growth and social outcome.

Results

The primary diseases included congenital anomalies of the kidney and urinary tract (n= 47, 44.3%), focal segmental glomerulosclerosis (n= 19, 17.9%), congenital nephrotic syndrome (n= 5, 4.7%), and other conditions. Ratio of functioning graft at the last follow-up was 81.8%; 76 patients (68.9%) had first graft, 11 patients had second graft, and 2 patients had third graft. Average estimated GFR was 51.0±20.5 ml/min/1.73m². Twenty patients received dialysis for graft failure; 19 patients for hemodialysis and one for peritoneal dialysis. Final height of males and females were 158.1±9.2 cm (-2.2±1.6 SD) and 149.1±6.4 cm (-1.7±1.２ SD), respectively. Fifty-eight (70.1%) patients excluded 24 students worked; 34 patients were office worker, 7 were medical related work, and others. Fourteen patients (19.5%) got married; males and females were 3 and 11, respectively. Three females of thirties and two females of forties had one child each.

Conclusions

Favorable graft survival rate was noted in this study. Final height was not enough, particularly in male patients. The rate of employment (70.1%) was relatively high, but marriage and childbearing rate were still low in this era. Improving social outcome will be one of the important problems after pediatric KTx.

CITATION INFORMATION: Hamasaki Y., Matsuda T., Kubota M., Hashimoto J., Takahashi Y., Muramatsu M., Kawamura T., Sakai K., Shishido S. Long-Term Social Outcome after Pediatric Kidney Transplantation Am J Transplant. 2017;17 (suppl 3).

To cite this abstract in AMA style:

Hamasaki Y, Matsuda T, Kubota M, Hashimoto J, Takahashi Y, Muramatsu M, Kawamura T, Sakai K, Shishido S. Long-Term Social Outcome after Pediatric Kidney Transplantation [abstract]. https://atcmeetingabstracts.com/abstract/long-term-social-outcome-after-pediatric-kidney-transplantation/. Accessed May 16, 2025.

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