ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Kidney Transplant Outcomes in Patients with ESRD Due to Myeloma

A. Riaz, A. Khalil, M. S. Yaqub, T. Taber, O. Adebiyi, A. Sharfuddin

Indiana University School of Medicine, Indianapolis, IN

Meeting: 2019 American Transplant Congress

Abstract number: D341

Keywords: Kidney transplantation, Malignancy, Mortality

Session Information

Date: Tuesday, June 4, 2019

Session Name: Poster Session D: PTLD/Malignancies: All Topics

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

Related Abstracts
  • A Novel Protocol to Improve Kidney Transplant Outcomes in Patients with Renal Disease Due to Amyloidosis
  • Patients with ESRD Due to Diabetes Have Higher Variability of Their Tacrolimus Levels and Worse Outcomes.

*Purpose: Recent literature has suggested that certain patients with multiple myeloma can successfully undergo renal transplantation after stem transplantation with consideration for maintenance therapy. Outcomes of Patients with ESRD due to Myeloma has not been studied extensively. As more and more patients are surviving longer and becoming eligible for transplantation, we examined the outcomes of this population.

*Methods: The UNOS/OPTN database was analyzed for all cases from 1998 to 2017 for ESRD due to Myeloma (Code 3023). Multi-organ transplants were excluded.

*Results: A total of 176 cases were identified. 1,3,5, 10 year uncensored graft survival was 97,86,68,37 % respectively, whereas death-censored graft survival was 98,95,93,89 % respectively. The patient survival was 99,92, 74 37% at 1,3,5,10 years respectively. There was no difference in graft survival between AA vs Caucasians, Living vs Deceased Donor Transplants or those with or without DGF. (p=0.41). However there was in inferior survival amongst male recipients compared to females (p=0.033).

*Conclusions: We conclude that with careful selection, eligible patients with treated Myeloma have favorable outcomes compared to other non-Myeloma recipients. They tend to have a very low rate of Acute rejections. Further studies are needed to look at other outcomes which may impact survival such as recurrence of myeloma. To our knowledge this is the largest and first study analyzing the outcomes of these patients in the US.

Demographics
Variable Results
Mean age at time of Transplant 53.7+/-10.0
Mean Donor Age 43.2+/-14.5
Mean BMI 25.9+/-4.6
Mean Cold Ischemia Time (hrs) 11.0+/-11.9
Median WaitingTime (days) 257 (IQR67-676)
DM (%) 2.8
ECD (%) 4.5
Results
Caucasians/ AA (%) 82.4/6.3
DGF (%) 11.4
GenderM/F (%) 54.5 / 45.5
Zero MM (%) 16.5
DCD (%) 5.7
On Dialysistime of Transplant (%) 68.8
Deceased / Living Donor (%) 44.8 / 55.1 
1 yr Rejection (%) 2.8

 border=

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Riaz A, Khalil A, Yaqub MS, Taber T, Adebiyi O, Sharfuddin A. Kidney Transplant Outcomes in Patients with ESRD Due to Myeloma [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/kidney-transplant-outcomes-in-patients-with-esrd-due-to-myeloma/. Accessed March 9, 2021.

« Back to 2019 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.