ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Intestinal Insufficiency May Affect Outcomes After Pediatric Liver Transplantation

A. K. Batra, M. Desai, J. Yang, K. Cummins, H. Oden-Brunson, H. Ling, S. Beer, J. Goss, N. Galvan

Surgery, Baylor College of Medicine, Houston, TX

Meeting: 2021 American Transplant Congress

Abstract number: LB 88

Keywords: Adverse effects, Liver, Mortality, Post-operative complications

Topic: Clinical Science » Liver » Liver: Pediatrics

Session Information

Session Name: Liver: Pediatrics

Session Type: Poster Abstract

Session Date & Time: None. Available on demand.

Location: Virtual

*Purpose: The purpose of this study is to determine if pre-transplant feeding intolerance is associated with poorer post-OLT (orthotopic liver transplant) outcomes in pediatric liver transplant recipients, in the setting of limited published literature on the relationship between intestinal integrity and liver transplant outcomes.

*Methods: A retrospective cohort study was performed on 248 pediatric patients who received orthotopic liver transplants between 2012 and 2019. 59 variables were collected which included lab values and perioperative complications such as thrombotic events, post-transplant infection, repeat laparotomy, ascites, gastrointestinal bleed (GI), and renal support. Patients were then categorized into feeding tolerant (n=154, n=171 pre- and post-op, respectively) or intolerant (n=94, n=77 pre-op and post-op, respectively) groups, based on several factors including their tolerance of feeds by mouth, tube feeds, or total parental nutrition. Chi-square tests were used to analyze the association between pre-transplant feeding intolerance and each of the outcome variables. Kaplan-Meier survival curves demonstrated 99% and 97% survival at 1 and 6 years in the feeding tolerant group, respectively, and 86% and 79% survival in the feeding intolerant group at 1 and 6 years, respectively.

*Results: Bivariate analysis showed that pre-transplant feeding intolerance was significantly associated with post-transplant feeding intolerance, hepatic artery thrombosis, portal vein thrombosis, renal support, prolonged intubation, post-transplant infection, ascites, GI bleed, mortality, at a significance level of .05 for each. Variables that were assessed for association but were not found to be significantly associated include repeat laparotomy and ileus.

*Conclusions: The results showed that pre-transplant feeding intolerance is associated with multiple post-transplant abdominal complications such as mortality and post-transplant infection. The implications of this highlights the importance of intestinal integrity reflected as feeding tolerance as a guide to perioperative risk stratification and care.

 border=

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

To cite this abstract in AMA style:

Batra AK, Desai M, Yang J, Cummins K, Oden-Brunson H, Ling H, Beer S, Goss J, Galvan N. Intestinal Insufficiency May Affect Outcomes After Pediatric Liver Transplantation [abstract]. Am J Transplant. 2021; 21 (suppl 3). https://atcmeetingabstracts.com/abstract/intestinal-insufficiency-may-affect-outcomes-after-pediatric-liver-transplantation/. Accessed June 1, 2025.

« Back to 2021 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences