Influence of Controlled Donation After Circulatory Death (cdcd) on Waiting List Mortalityfor Liver Transplantation in the Last 10 Years: The Spanish Experience
University Hospital Virgen Arrixaca (IMIB-Arrixaca), Murcia, Spain
Meeting: 2021 American Transplant Congress
Abstract number: 1134
Keywords: Donation, Donors, non-heart-beating, Liver, Waiting lists
Topic: Clinical Science » Liver » Liver: MELD, Allocation and Donor Issues (DCD/ECD)
Session Information
Session Name: Liver: MELD, Allocation and Donor Issues (DCD/ECD)
Session Type: Poster Abstract
Session Date & Time: None. Available on demand.
Location: Virtual
*Purpose: Controlled donation after circulatory death (cDCD) provides one third of liver donors in Spain nowadays. The aim of our work is to evaluate the impact that cDCD has had on the evolution of mortality on the waiting list for liver transplant at our hospital over the last 10 years.
*Methods: We retrospectively analyzed liver donation and transplant activity data at our center over the past 10 years through our records and those of the Spanish National Transplant Organization (ONT).
*Results: Figure 1 shows the percentages of patients on the liver transplant waiting list who were transplanted, dropped-out from the list, or died on the list during the last 10 years (2010-2019). It should be noted that in the pre-cDCD era (before 2014) the mortality rate on the list was above 20%. However, in the age of controlled-DCD (from 2014 onwards) this percentage has decreased to 6% in 2019. As for the probability of liver transplantation per year (Figure 2), it has remained in progressive ascent despite the high rate of indication for liveer transplantation in our group (69.4 pmp, year 2018), the highest in Spain.The successful introduction of the controlled donation after circulatory death program at our hospital has reduced the mortality rate on the waiting list for liver transplants by 19% in 5 years. The probability of liver transplantation per year has increased by up to 20%.
*Conclusions: Therefore, cDCD has allowed us to significantly reduce mortality on the waiting list for liver transplantation.
To cite this abstract in AMA style:
Alconchel F, Royo-Villanova M, Moya J, Martínez-Alarcón L, Zambudio J, Cascales-Campos P, Nicolás T, Robles R, Sánchez-Bueno F, Pons J, Rodríguez J, Ríos A, Fernández J, Ramírez P. Influence of Controlled Donation After Circulatory Death (cdcd) on Waiting List Mortalityfor Liver Transplantation in the Last 10 Years: The Spanish Experience [abstract]. Am J Transplant. 2021; 21 (suppl 3). https://atcmeetingabstracts.com/abstract/influence-of-controlled-donation-after-circulatory-death-cdcd-on-waiting-list-mortalityfor-liver-transplantation-in-the-last-10-years-the-spanish-experience/. Accessed December 12, 2024.« Back to 2021 American Transplant Congress