ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Improving Pre-Kidney Transplantion Laboratory Utilization in an Era of Increasing Waitlist Size

G. K. Mahowald1, B. Kimball2, N. Elias2, E. Heher3, T. Girouard1, S. L. Saidman1, V. Pattanayak1

1Pathology, Massachusetts General Hospital, Boston, MA, 2Transplant Surgery, Massachusetts General Hospital, Boston, MA, 3Nephrology, Massachusetts General Hospital, Boston, MA

Meeting: 2019 American Transplant Congress

Abstract number: C6

Keywords: HLA antibodies, Kidney transplantation, Screening, Waiting lists

Session Information

Date: Monday, June 3, 2019

Session Name: Poster Session C: Histocompatibility and Immunogenetics

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

Related Abstracts
  • Kidney & Pancreas Transplant Waitlist Management – A Tiered System Approach
  • Four Eyes Are Better Than Two: Improving Laboratory Report Quality Control

*Purpose: Beginning on March 25, 2015, our institution’s kidney transplant program has implemented a “readiness” protocol, whereby patients are listed after limited workup and comprehensive testing is deferred until the anticipated time to transplantation is approximately 6-12 months. Prior to implementation of this protocol, our histocompatibility laboratory would receive monthly sera for anti-HLA antibody screening immediately upon listing. However, as part of the readiness strategy, the lab now requests monthly samples only when a candidate is predicted to have 6-12 months of waitlist time remaining.

*Methods: Data from our laboratory database and UNOS were analyzed to determine the number of samples received from waitlisted kidney transplant candidates and the number tested in the three-year period before and after implementation of the readiness protocol.

*Results: Our kidney transplant waitlist has grown from 379 candidates in 2012 to >1000 in 2018. Despite this rapid growth, the number of samples received from kidney transplant candidates has decreased from 9171 during the three-year period prior to the implementation of readiness (~3057/year) to 7924 during the subsequent three-year period (~2641/year). Based on a sample submission rate of ~7 samples/patient/year, an estimated 5425 samples per year would have been received without the readiness protocol, with an estimated 6979 samples expected for 2018. From 3/25/12-3/24/15, 4730 antibody screening tests on kidney waitlist candidates were performed by Luminex (~1577 tests/year), compared to a slight increase to 5082 from 3/25/15-3/24/18 (~1694 tests/year), despite a 2.6-fold increase in patients on the waitlist from 2012-2018. When adjusted for the number of waitlist candidates in each time period, the percentage of candidates being passed over for an organ offer due to an 812 code (no serum sample) is comparable before and after readiness.

*Conclusions: Implementation of the readiness protocol has streamlined the pre-transplant testing process and reduced both the number of samples received and the number tested, with minimal effect on missed organ offers due to lack of a current sample. This strategy has allowed us to manage a greatly increased waitlist with the same level of resources and has resulted in reduced cost per patient.

 border=

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Mahowald GK, Kimball B, Elias N, Heher E, Girouard T, Saidman SL, Pattanayak V. Improving Pre-Kidney Transplantion Laboratory Utilization in an Era of Increasing Waitlist Size [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/improving-pre-kidney-transplantion-laboratory-utilization-in-an-era-of-increasing-waitlist-size/. Accessed December 13, 2019.

« Back to 2019 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Penis Transplantation: First U.S. Experience.
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Tacrolimus Dose and Trough Blood Levels in a US Liver Transplant Population
  • Penis Transplantation: First U.S. Experience.
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Tacrolimus Dose and Trough Blood Levels in a US Liver Transplant Population
  • Penis Transplantation: First U.S. Experience.

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2019 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

wiley-new-logo

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.