ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Early Graft Function and Intrarenal Resistant Index after Kidney Transplantation Using New Preservation Fluid (Biolasol)

A. Kolonko1, R. Król2, J. Chudek3, L. Cierpka2, A. Więcek1

1Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland, 2General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland, 3Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice, Poland

Meeting: 2020 American Transplant Congress

Abstract number: C-105

Keywords: Graft function, Kidney, Preservation solutions, Ultrasonography

Session Information

Session Name: Poster Session C: Kidney Technical

Session Type: Poster Session

Date: Saturday, May 30, 2020

Session Time: 3:15pm-4:00pm

 Presentation Time: 3:30pm-4:00pm

Location: Virtual

*Purpose: Biolasol is a newly developed preserving solution for cold organ storage prior to transplantation. The aim of this study was to compare in the clinical settings the early post-transplant course of kidney grafts preserved with Biolasol in comparison with traditional used preservation solutions.

*Methods: One-hundred-seventy-three organs were preserved before transplantation using Biolasol and 173 organs were preserved with traditionally used solutions (UW, IGL or Store Protect). Early graft function was defined based on serum creatinine concentration at 3rd day (<3 mg/dl - immediate graft function, IGF or >3 mg/dl – slow graft function, SGF) or the need of dialysis therapy during first postoperative week (delayed graft function, DGF). The analysis included intrarenal resistive indices measured by Doppler sonography few days after transplantation and before discharge from the hospital.

*Results: IGF was more frequent in patients with organs preserved with traditional solutions (28.3 vs. 18.5%, p=0.03), whereas there was no difference in the occurrence of DGF. Both initial and discharge median resistance index values were significantly higher in the Biolasol group (0.77 vs. 0.70 and 0.75 vs. 0.69, respectively, both p<0.001). Median serum creatinine concentrations were higher in the Biolasol group (post-transplant day 3: 524 vs. 476, p<0.05, day 7: 270 vs. 206, p<0.05 and at discharge: 147 vs. 130 µmol/l, p<0.01). Multiple logistic regression analysis revealed that ECD status [OR 0.28 (95%CI: 0.14-0.56)], CIT >18 h [OR 0.52 (0.32-0.83) and the use of Biolasol solution [OR 0.47 (0.29-0.75)] were independently decreasing the occurrence of IGF.

*Conclusions: In this first clinical application in a large cohort of kidney transplanted patients, kidney preservation using Biolasol solution was associated with significantly worse early graft function and higher intrarenal resistant index in comparison with traditional preservation fluids. Long term follow-up is needed in order to assess the kidney graft and patient survival.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Kolonko A, Król R, Chudek J, Cierpka L, Więcek A. Early Graft Function and Intrarenal Resistant Index after Kidney Transplantation Using New Preservation Fluid (Biolasol) [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/early-graft-function-and-intrarenal-resistant-index-after-kidney-transplantation-using-new-preservation-fluid-biolasol/. Accessed May 9, 2025.

« Back to 2020 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences