Cardiovascular Risk Factors in Patients after Liver Transplantion

M. Adamczak¹, D. Gojowy¹, J. Stompor¹, J. Adamusik¹, G. Smiech¹, H. Karkoszka¹, R. Krol², A. Wiecek¹

¹Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland, ²Department of General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland

Meeting: 2020 American Transplant Congress

Abstract number: B-151

Keywords: Hyperglycemia, Hyperlipidemia, Hypertension, Liver transplantation

Topic:

Session Information

Session Name: Poster Session B: Liver Retransplantation and Other Complications

Date: Saturday, May 30, 2020

Session Time: 3:15pm-4:00pm

Presentation Time: 3:30pm-4:00pm

Location: Virtual

*Purpose: The aim of this study was to estimate the prevalence of selected cardiovascular risk factors in patients after liver transplantation (LTx).

*Methods: Medical records from 130 patients aged 49.3 ± 11.9 years (52F, 78M) before and 2 years after LTx were analysed. The prevalence of diabetes mellitus, arterial hypertension, hypertriglyceridemia, hypercholesterolemia, obesity and cigarette smoking were estimated. Among the studied population, 3 groups of the most common aetiology of liver cirrhosis (alcoholic, viral, autoimmune) were selected.

*Results: The prevalence of diabetes mellitus before and 2 years after LTx was 18% and 48%, respectively (P < 0.001). Arterial hypertension - 24% and 70% (P < 0.001), hypertriglyceridemia - 15% and 38% (P < 0.001), hypercholesterolemia - 16% and 46% (p<0.001) of patients before and 2 years after LTx, respectively. 13% and 18% of patients were obese before and 2 years after LTx, respectively. Cigarette smoking was admitted by 24% before LTx and 10% of patients 2 years after LTx (P < 0.001). In patients with an autoimmune cause of liver cirrhosis in comparison to patients with alcoholic disease diabetes (38% vs 67%, P = 0.02), hypertriglyceridemia (19% vs 63%, P < 0.001), hypercholesterolemia (28% vs 67%, P = 0.002) and obesity (9% vs 33%, P = 0.02) occurred only rarely.

*Conclusions: 1. Prevalence of arterial hypertension and abnormalities of glucose and lipid metabolism increase significantly after LTx. 2. The aetiology of liver cirrhosis before transplantation may influence the prevalence of cardiovascular risk factors in patients after LTx.

To cite this abstract in AMA style:

Adamczak M, Gojowy D, Stompor J, Adamusik J, Smiech G, Karkoszka H, Krol R, Wiecek A. Cardiovascular Risk Factors in Patients after Liver Transplantion [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/cardiovascular-risk-factors-in-patients-after-liver-transplantion/. Accessed May 17, 2021.

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