DCD vs DBD Liver Transplantation: Equivalent Charges and Similar Survival- An Effective Expansion of the Donor Pool
Ohio State University, Columbus, OH
Meeting: 2020 American Transplant Congress
Abstract number: D-108
Keywords: Donors, marginal, Graft function, Liver transplantation, Warm ischemia
Session Information
Session Name: Poster Session D: Liver: MELD, Allocation and Donor Issues (DCD/ECD)
Session Type: Poster Session
Date: Saturday, May 30, 2020
Session Time: 3:15pm-4:00pm
Presentation Time: 3:30pm-4:00pm
Location: Virtual
*Purpose: The shortage of allografts available for liver transplantation (LT) has prompted the need for expansion of donor pool to include donation after circulatory death (DCD). Despite the increasing utilization of DCD livers, limited data is available pertaining to the charges of DCD transplant and comparing it with that of DBD transplant
*Methods: Data were obtained on adult patients who underwent LT at The Ohio State University Comprehensive Transplant Center from November 2016 until May 2019. Exclusion criteria included multi-organ transplants and re-transplants.Patient and graft survival,Length of stay (LOS) following transplantation, readmissions, and postoperative care charges during the six months following transplantation were compared between DCD and DBD livers recipients using Mann-Whitney U tests for distributional differences and Fisher Exact tests. Graft and recipient survival were compared using Kaplan-Meier curves and log-rank tests. Mann-Whitney U equivalence tests were conducted to assess DBD and DCD equivalence in charges at index admission and from discharge to 6-months post transplant.
*Results: Our study included 247 patients ( 208 DBD, 39 DCD ) with demographics and outcomes shown in Table 1. There were no significant differences in patient and graft survival, LOS, readmissions, and postoperative care. Charges for index admission and from discharge to 6-months post-transplant were equivalent between the DCD and DBD Liver transplant .
*Conclusions: Our results provide evidence suggesting recipients of DCD allografts have similar outcomes to those of DBD grafts. The charges associated with care for DBD and DCD are equivalent. DCD liver allografts should be considered comparable to DBD grafts when used in a systematic fashion. Our contemporary cohorts provide evidence of DCD liver allografts as a safe, cost-effective expansion of the donor pool.
To cite this abstract in AMA style:
Singh N, Helfrich K, Alebrahim M, Akateh C, Mumtaz K, Logan A, Schenk A, Black S, Elkhammas E, Washburn K, El-Hinnawi A. DCD vs DBD Liver Transplantation: Equivalent Charges and Similar Survival- An Effective Expansion of the Donor Pool [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/dcd-vs-dbd-liver-transplantation-equivalent-charges-and-similar-survival-an-effective-expansion-of-the-donor-pool/. Accessed November 22, 2024.« Back to 2020 American Transplant Congress