2018 American Transplant Congress
Detection of Different Gene Expression Profiles in CD8+ T Cells from Chronic High EBV Load Carriers after Pediatric Heart and Liver Transplantation
Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). The risk for PTLD varies by transplanted organ,…2018 American Transplant Congress
Characterization of Viral and Host Cell Genomic Alterations in EBV+ PTLD
1Abdominal Transplant, Stanford University, Stanford; 2Pathology, Stanford University, Stanford.
Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation characterized by abnormal proliferation of lymphoid cells in the setting of immunosuppression after…2018 American Transplant Congress
Peptides Encoded by EBV Latent Cycle Proteins Affect NK Cell Reactivity
Department of Surgery, Stanford University School of Medicine, Stanford, CA.
Introduction: Epstein–Barr virus (EBV) infects more than 90% of adults worldwide and is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). Although EBV infection…2018 American Transplant Congress
Follow-Up and Outcomes of Epstein-Barr Virus Negative Recipients after a Kidney Transplant from an Epstein-Barr Virus Positive Donor
Introduction: Post-transplant lymphoproliferative disorder (PTLD) is one of the most serious complications of chronic immunosuppression after an organ transplant. One of the major risk factors…2018 American Transplant Congress
Use of Cyclin-Dependent Kinase Inhibitors to Reduce Gammaherpesvirus Reactivation
Infection with the gammaherpesvirus EBV occurs in over 90% of humans and leads to lifelong viral latency with intermittent reactivation that is typically controlled through…2018 American Transplant Congress
Presentation and Outcomes of Post-Transplant Proliferative Disorder at a Single Institution Pediatric Transplant Center
Purpose: The aim of this study was to characterize features present at the time of post-transplant lymphoproliferative disorder (PTLD) diagnosis, as well as outcomes, following…2018 American Transplant Congress
Post-Transplant Lymphoproliferative Disorder after Kidney Transplantation: A Single Institute Experience with Focus on Epstein-Barr Virus Status
Background: Comparing to other types of solid organ transplant, the Post-Transplant Lymphopro- liferative Disorder (PTLD) in kidney transplant recipients (KTRs) is relatively rare. Due to…2018 American Transplant Congress
Sirolimus Use Improves Cancer-Free Survival Following Transplantation: A Single Center 10-Year Analysis
Introduction:In previous published results, we showed that the use of Sirolimus-based immunosuppression regimens had equivalent patient and graft 10-year survival compared to historical controls maintained…2018 American Transplant Congress
Multi-Visceral Transplant in an HIV Positive Recipient – One Year Survival
Surgery, Indiana University School of Medicine, Indianapolis, IN.
Human immunodeficiency virus (HIV) is associated with hypercoagulability and thrombotic events. Highly active anti-retroviral therapy (HAART) has improved long term survival. More patients with HIV…2018 American Transplant Congress
Genomic Modifications Associated with Epstein Barr Virus+ Post-Transplant Lymphoproliferative Disorder
Epstein Barr Virus (EBV) is nearly ubiquitous in the human population, yet EBV infection is typically asymptomatic. Nevertheless, immunosuppressed transplant recipients are susceptible to EBV+…
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