Articles tagged "Weight"

2020 American Transplant Congress
Serum Cystatin C Predicts Kidney-Related Outcomes and Transplant-Free Survival in Patients with End-Stage Liver Disease and Low Body Mass Index
N. Shankar¹, M. Garcia Saenz de Sicilia², A. Duarte-Rojo³, S. K. Asrani⁴, J. F. Trotter⁴, G. B. Klintmalm⁴, B. V. Fischbach⁵, S. A. Gonzalez⁵
¹Internal Medicine, Baylor Scott & White University Medical Center, Dallas, TX, ²University of Arkansas for Medical Sciences, Little Rock, AR, ³Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Center for Liver Diseases, Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA, ⁴Baylor Simmons Transplant Institute, Dallas, TX, ⁵Baylor Simmons Transplant Institute, Fort Worth, TX
*Purpose: Liver transplant (LT) candidates with sarcopenia are disadvantaged by creatinine-based assessment of renal function as creatinine overestimates glomerular filtration rate (GFR). Low body mass…
2020 American Transplant Congress
Liver Transplantation in Obese Recipients: Post-Transplant Weight Gain and Outcomes
D. Soma¹, Y. Park¹, P. Mihaylov¹, B. Ekser¹, M. S. Ghabril², M. A. Lacerda², N. Chalasani², R. S. Mangus¹, C. A. Kubal¹
¹Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, ²Transplant Hepatology, Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, IN
*Purpose: Non-alcoholic fatty liver disease is now the most common cause of end-stage liver disease necessitating orthotopic liver transplantation (OLT) in the United States. Several…
2020 American Transplant Congress
The Influence of Donor Kidney to Recipient Body Weight Ratio on Long-Term Outcomes of Living-Donor Kidney Transplantation
N. Sato, Y. Kakuta, T. Kanzawa, K. Unagami, M. Okumi, H. Ishida, K. Tanabe
Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
*Purpose: We often experience the incompatibility in size between the kidney graft and recipient in living-donor kidney transplantation. This study evaluated the effect of the…
2020 American Transplant Congress
Should Steatotic Livers Be Transplanted Into Pediatric Recipients?
M. MacConmara, C. Feizpour, P. Vagefi, C. Ramirez, L. DeGregorio, C. S. Hwang
UT Southwestern, Dallas, TX
*Purpose: Although steatotic livers are frequently transplanted in the adult population, they are not commonly transplanted in pediatric recipients. We questioned if the outcomes of…
2020 American Transplant Congress
Outcomes Associated with Mycophenolate Weight-Based Dosing in Varying Immunologic Risk Kidney Transplant Recipients
A. A. Al-Bahou, A. R. Webb, M. Bloxam, L. J. Bowman Anger, R. S. Baliga, A. J. Brueckner
Tampa General Hospital, Tampa, FL
*Purpose: Mycophenolate acid (MPA) is traditionally dosed in kidney transplant recipients (KTR) using the FDA-approved fixed dosing which is irrespective of patient-specific variables such as…
2019 American Transplant Congress
Lifestyle Intervention in Renal Transplant Recipients: A Multicenter, Randomized Clinical Trial
E. Corpeleijn¹, G. Klaassen², D. M. Zelle², D. Dijkema³, I. van Vliet², F. J. Bemelman⁴, G. J. Navis², S. J. Bakker²
¹Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands, ²Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands, ³Department of Dietetics, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Nephrology, Amsterdam Medical Center, Amsterdam, Netherlands
*Purpose: Low physical activity and reduced physical functioning are common after renal transplantation, resulting in a reduced quality of life. The aim of this study…
2019 American Transplant Congress
Undernutrition is Associated with Impaired T Cell Protective Immunity in Pediatric Kidney Transplantation
E. T. Chambers¹, C. Chan¹, R. Ettenger², P. Grimm³, E. Reed², M. Sarwal⁴, L. Stempora⁵, B. Warshaw⁶, C. Zhao¹, O. Martinez⁷, A. Kirk⁵
¹Pediatrics, Duke University, Durham, NC, ²Pediatrics, UCLA, Los Angeles, CA, ³Pediatrics, Stanford, Palo Alto, CA, ⁴Pediatrics, UCSF, San Francisco, CA, ⁵Surgery, Duke University, Durham, NC, ⁶Pediatrics, Emory University, Atlanta, GA, ⁷Surgery, Stanford, Palo Alto, CA
*Purpose: Undernutrition has been associated with T cell immune cell dysfunction and infectious complications in non-immunosuppressed children. Thus, we aimed to define T cell phenotypes…
2019 American Transplant Congress
Undernutrition and Leptin Deficiency Modulates T Cell Immunity in Transplantation
E. David¹, M. Zhu², B. Bennett², D. Cheng¹, A. Nichols¹, W. Parker², P. Schroder², N. McIver¹, A. Kirk², E. Chambers¹
¹Pediatrics, Duke University, Durham, NC, ²Surgery, Duke University, Durham, NC
*Purpose: We have previously shown an association between undernutrition and the development of viremia in transplanted children. While undernutrition is associated with impaired T cell…
2019 American Transplant Congress
Expression of Prostaglandin E2 Receptors Track with Rejection in Porcine Kidney Transplants
A. Harner¹, Y. Wang², X. Fang², R. Lassiter¹, T. D. Merchen¹, S. Ho³, S. Nahman Jr²
¹Surgery, Augusta University, Augusta, GA, ²Nephrology, Augusta University, Augusta, GA, ³Gift of Life Michigan, Ann Arbor, MI
*Purpose: Prostaglandin E2 (PGE2) is generated from arachidonic acid via cyclooxygenase-2 (COX2) and is known to modulate the immune response via its receptors: EP1, EP2,…
2019 American Transplant Congress
Feasibility of a Rapid Magnetic Resonance Protocol to Assess Body Composition Profiles in Adult Liver Transplant Candidates
S. Pine¹, L. Adamski¹, D. Gregory¹, C. Padilla¹, J. Gottstein², A. Lemmer¹, M. Forsgren³, M. Rinella¹, L. B. VanWagner⁴
¹Medicine-GI & Hepatology, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Center for Medical Image Science, Linköping University, Linköping, Sweden, ⁴Medicine-GI & Hepatology and Preventive Medicine, Northwestern University, Chicago, IL
*Purpose: Body mass index (BMI) is a poor marker of obesity and outcomes in liver transplant (LT) candidates. Data suggest that body composition profiling (BCP),…