ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Warm ischemia"

  • 2020 American Transplant Congress

    DCD vs DBD Liver Transplantation: Equivalent Charges and Similar Survival- An Effective Expansion of the Donor Pool

    N. Singh, K. Helfrich, M. Alebrahim, C. Akateh, K. Mumtaz, A. Logan, A. Schenk, S. Black, E. Elkhammas, K. Washburn, A. El-Hinnawi

    Ohio State University, Columbus, OH

    *Purpose: The shortage of allografts available for liver transplantation (LT) has prompted the need for expansion of donor pool to include donation after circulatory death…
  • 2020 American Transplant Congress

    Activation of YAP Attenuates Hepatic Damage and Fibrosis in Liver Ischemia-Reperfusion Injury: From Bench to Bedside

    Y. Liu1, T. Lu2, C. Zhang1, Z. Xue1, R. Busuttil1, J. Kupiec-Weglinski1, H. Ji1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2Shanghai Jiaotong University, Shanghai, China

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, the effector of Hippo pathway, is essential in…
  • 2020 American Transplant Congress

    Genome-Wide Transcriptome Analysis of Extreme Marginal Renal Grafts Indicates Earlier Repair and Less Damage Following Normothermic Ex-Vivo Kidney Perfusion Preservation

    P. Urbanellis1, L. Mazilescu1, C. McEvoy1, S. Ganesh1, R. John1, I. Mucsi1, A. Ghanekar1, D. Bagli2, A. Konvalinka1, L. Robinson1, M. Selzner1

    1University Health Network, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada

    *Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) was shown to prevent delayed graft function of kidneys subjected to prolonged warm ischemia (WI) compared to static cold…
  • 2020 American Transplant Congress

    Potential to Regenerate Damaged Allografts

    L. Brasile1, B. Stubentisky2

    1Research and Development, Breonics Inc., Watervliet, NY, 2Plastic, Reconstructive & Aesthetic Surgery, St. Antonius Hospital, Utrecht, Netherlands

    *Purpose: The chronic shortage of allografts has generated intense interest in the field of regenerative medicine. Given the limited regeneration that can be accomplished in…
  • 2020 American Transplant Congress

    HMGB1 Antagonizes the Immunosuppressive Effect of MSCs in AKI

    S. Cai1, S. Wang2, W. Zhang2, A. Chandraker1, C. Yang2, T. Zhu2

    1Renal Division, Brigham and Women's Hospital, Boston, MA, 2Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China

    *Purpose: Kidney ischemia reperfusion injury (IRI) is a common cause of acute kidney injury and an unavoidable consequence of kidney transplantation and still lacks specific…
  • 2019 American Transplant Congress

    Robotic-Assisted versus Open Techniques for Living Donor Kidney Transplant Recipients: A Comparison Using Propensity Score Analysis

    F. Tinney, J. Stracke, S. Nagai, L. Malinzak, T. McEvoy, S. Mohamed Ilias, A. Yoshida

    Transplant Institute, Henry Ford Hospital, Detroit, MI

    *Purpose: Following rapid advancements in minimally invasive urology, living donor robotic-assisted kidney transplantation (RAKT) has developed into a feasible alternative to open kidney transplantation (OKT).…
  • 2019 American Transplant Congress

    Utilization of DCD Donors >50 Years Old for Liver Transplantation

    T. Chaly, K. Hoidal, C. Cashman, J. Brink, A. Mehrotra, W. Van der Werf

    Arizona Transplant Associates, PC, Phoenix, AZ

    *Purpose: End stage liver disease is becoming more prevalent in the United States with approximately 4.9 million adults carrying the diagnosis. It is estimated that…
  • 2019 American Transplant Congress

    Histone Deacetylase-2 Knockout in Renal Tubular Cells is Protective in Renal Ischemia-Reperfusion Injury

    P. T. Hernandez1, S. J. Concors1, L. Krumeich1, D. D. Aufhauser1, Z. Wang1, D. D. Murken1, G. Ge1, W. Hancock2, M. Levine3

    1General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, 3Transplant Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Ischemia-reperfusion injury (IRI) is a major source of morbidity in renal transplantation and is without targeted therapy. In renal transplantation, IRI contributes to poorer…
  • 2019 American Transplant Congress

    Incidence of Autoresuscitation in Donation after Cardiac Death Donors

    C. W. Koo1, R. A. Helmick1, K. Van Frank2, K. Gilley2, J. D. Eason1

    1UTHSC / Methodist University Hospital Transplant Institute, Memphis, TN, 2Mid South Transplant Foundation, Memphis, TN

    *Purpose: Donation after cardiac death (DCD) donors are subject to an observation period after asystole to monitor for cardiopulmonary autoresuscitation (AR). Periods vary between and…
  • 2019 American Transplant Congress

    Effects of Static Subnormothermic Preservation of Extended Warm Ischemic Porcine Kidneys Assessed by Ex-Vivo Machine Perfusion and Renal Transplant Model

    H. Sahara, Y. Ariyoshi, M. Sekijima, T. Iwanaga, A. Shimizu, K. Yamada

    Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan

    *Purpose: The donation after circulatory death (DCD) donors has the potential to match the increasing need for transplantable organs, however, DCD kidneys have a higher…
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