2020 American Transplant Congress
HMGB1 Antagonizes the Immunosuppressive Effect of MSCs in AKI
*Purpose: Kidney ischemia reperfusion injury (IRI) is a common cause of acute kidney injury and an unavoidable consequence of kidney transplantation and still lacks specific…2020 American Transplant Congress
Short Recipient Warm Ischemia Time Improves Graft Survival in Liver Transplantation from Donation after Brain Death: 20-Year Experience of Liver Transplantation
Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Although the correlation between warm ischemia time (WIT) and the outcomes of liver transplantation has been extensively studied, few investigations have focused on the…2020 American Transplant Congress
Benefits of Normothermia Regional Perfusion (NRP), Hypothermic Machine Perfusion (HMP) and Short Cold Ischemia Time (CIT) for Kidney Transplants with Controlled Donation after Circulatory Death (cDCD)
*Purpose: cDCD are considered as extended criteria donors with poorer kidney transplant outcomes and high delayed graft function (DGF) rate. We built a French national…2020 American Transplant Congress
Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers
Surgery, Washington University St. Louis, St. Louis, MO
*Purpose: Aged livers are far more susceptible to ischemia/reperfusion (I/R) injury than young livers. No therapeutic strategies are available to reduce I/R injury in elderly…2020 American Transplant Congress
Initial North American Experience in Renal Transplantation from Medical Assistance in Dying Donors
Surgery, London Health Sciences Centre, London, ON, Canada
*Purpose: In 2016, Canadian federal legislation was passed creating a regulatory framework for medical assistance in dying (MAiD) for individuals who are suffering from a…2019 American Transplant Congress
Histone Deacetylase-2 Knockout in Renal Tubular Cells is Protective in Renal Ischemia-Reperfusion Injury
*Purpose: Ischemia-reperfusion injury (IRI) is a major source of morbidity in renal transplantation and is without targeted therapy. In renal transplantation, IRI contributes to poorer…2019 American Transplant Congress
Incidence of Autoresuscitation in Donation after Cardiac Death Donors
*Purpose: Donation after cardiac death (DCD) donors are subject to an observation period after asystole to monitor for cardiopulmonary autoresuscitation (AR). Periods vary between and…2019 American Transplant Congress
Effects of Static Subnormothermic Preservation of Extended Warm Ischemic Porcine Kidneys Assessed by Ex-Vivo Machine Perfusion and Renal Transplant Model
Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan
*Purpose: The donation after circulatory death (DCD) donors has the potential to match the increasing need for transplantable organs, however, DCD kidneys have a higher…2019 American Transplant Congress
Cryopreserved Human Iliac Arteries Allografts: Different Thawing Rates Affect on Their Structural Changes and Mechanical Properties
*Purpose: The rate of thawing of cryopreserved human iliac arteries allografts (CHIAA) directly affects the severeness of structural changes that occur during this process. This…2019 American Transplant Congress
Inhibition of Cyclin-Dependent Kinase 2 Signaling Prevents Liver Ischemia and Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Hepatic ischemia/reperfusion injury (IRI), an exogenous antigen-independent local inflammation response, occurs in multiple clinical settings including liver transplantation, hepatic resection, trauma, and shock. The…
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