2020 American Transplant Congress
Initial North American Experience in Renal Transplantation from Medical Assistance in Dying Donors
Surgery, London Health Sciences Centre, London, ON, Canada
*Purpose: In 2016, Canadian federal legislation was passed creating a regulatory framework for medical assistance in dying (MAiD) for individuals who are suffering from a…2020 American Transplant Congress
The Learning Curve for Pure Laparoscopic Robotic Kidney Transplantation: An Analysis of Outcomes of the First 80 Consecutive Cases at a High-Volume Transplant Center
*Purpose: Robotic surgery is increasingly used in complex operations, including living-donor kidney transplantation. At this time, knowledge of the number of cases required to attain…2020 American Transplant Congress
Creation of a Low-Cost Kidney Transplant Surgery Simulator and Survey of its Utility for Education
Department of Surgery, Saint Louis University, Saint Louis, MO
*Purpose: Surgical skills education in transplant surgery is challenging as center-specific outcomes are scrutinized and trainees’ exposure to the sub-specialty is decreasing. Simulation could overcome…2020 American Transplant Congress
Type 1 Innate Lymphoid Cells Are Critical Pro-Inflammatory Effector Cells in a Fatty Liver Mouse Model of Ischemia-Reperfusion Injury
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis and immune regulation through the activation…2020 American Transplant Congress
The Impact of Transportation Innovation for Human Organs: Surgical Perspectives and Implications
Transplant Surgery, Unviersity of Maryland Medical Center, Baltimore, MD
*Purpose: Recent changes in allocation and the ongoing organ donor shortage have led to increased regional and national sharing, putting intense pressure on the organ…2019 American Transplant Congress
Inhibition of Cyclin-Dependent Kinase 2 Signaling Prevents Liver Ischemia and Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Hepatic ischemia/reperfusion injury (IRI), an exogenous antigen-independent local inflammation response, occurs in multiple clinical settings including liver transplantation, hepatic resection, trauma, and shock. The…2019 American Transplant Congress
Combined Ischemic and Rapamycin Preconditioning Alleviated Liver Ischemia and Reperfusion Injury by Restoring Autophagy in Old Mice
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Old livers are more damaged by hepatic ischemia and reperfusion (IR) injury than young livers. The aim of this study was to investigate the…2019 American Transplant Congress
Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant
1VCUHealth, Richmond, VA, 2Department of Surgery, VCUHealth, Richmond, VA
*Purpose: Epithelial-to-mesenchymal transition (EMT) is a genetic reprogramming that causes epithelial cells to assume a migratory, mesenchymal phenotype, and it is induced by hypoxia. Ischemic…2019 American Transplant Congress
Quantitative Proteomics Analysis of Ischemia Reperfusion Injured Liver Tissue Provides Insight into Liver Allograft Quality Evaluation
Transplant Center, Sun Yat-sen University, Guangzhou, China
*Purpose: Successful orthotopic liver transplantation (OLT) surgery mostly depends on good and functional liver donor, besides of mature transplant technology. The molecular basis of different…2019 American Transplant Congress
Sequestration of PLIN2 Regulates High-Fat Diet Induced Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in a Mouse Model of Ischemia Reperfusion Injury
*Purpose: This study aimed to define characteristics and mechanisms leading to nonalcoholic fatty liver disease and metabolic syndrome in a fatty liver mouse model that…
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