ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Viral therapy"

  • 2021 American Transplant Congress

    Leflunomide Therapy for Treatment of Bk Viremia in Pediatric Kidney Transplant Recipients

    A. Aldieri1, M. Chandran2, D. Matossian3, B. Magella4, D. Lazear4, M. Bock2, E. Blanchette2

    1Children's Hospital Colorado, Denver, CO, 2Children's Hospital Colorado, Aurora, CO, 3Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: BK viremia (BKV) after kidney transplantation (KT) poses significant risk for BK virus-associated nephropathy (BKVN) and impacts graft survival. Conventional treatment involves reduction of…
  • 2021 American Transplant Congress

    Influence of Induction Therapy and Antiretroviral Regimen on Outcomes in HIV Positive Renal Transplant Recipients

    C. Rogers Marks1, C. Durand2, J. Hand3, M. Abidi4, M. Malinis5, B. Barnaba2, H. Patel6, C. D. Alonso6

    1Massachussetts General Hospital, Boston, MA, 2Johns Hopkins Medical Center, Baltimore, MD, 3Ochsner Medical Center, New Orleans, LA, 4Univ. of Colorado, Aurora, CO, 5Yale, New Haven, CT, 6Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: Transplantation of HIV+ individuals has become more common over the past decade with increasing data supporting good outcomes. Questions remain regarding the impact of…
  • 2021 American Transplant Congress

    Monoclonal Antibody Therapy for COVID-19 in Solid Organ Transplant Recipients

    Z. A. Yetmar1, E. Beam1, J. C. O'Horo1, R. Ganesh2, D. M. Bierle2, L. Brumble3, M. T. Seville4, R. R. Razonable1

    1Infectious Diseases, Mayo Clinic, Rochester, MN, 2General Internal Medicine, Mayo Clinic, Rochester, MN, 3Infectious Diseases, Mayo Clinic, Jacksonville, FL, 4Infectious Diseases, Mayo Clinic, Scottsdale, AZ

    *Purpose: Bamlanivimab and casirivimab-imdevimab are authorized for emergency use treatment of mild-to-moderate COVID-19 in patients at high-risk for progression to severe disease or hospitalization. For…
  • 2021 American Transplant Congress

    Outcomes of Short-Duration Anti-Viral Prophylaxis for Hepatitis C Positive Donor Kidney Transplants

    G. Gupta, I. Yakubu, P. Kimball, L. Kang, K. Mitchell, M. Shinbashi, D. Kumar, I. Moinuddin, L. Kamal, A. King, C. Bhati, M. Levy, A. Cotterell, A. Sharma, R. Sterling

    Virginia Commonwealth University Health System, Richmond, VA

    *Purpose: Trials describing 4-12 week courses of direct-acting anti-viral drugs (DAAs) to treat hepatitis C virus (HCV) transmission from infected donors to uninfected kidney transplant…
  • 2021 American Transplant Congress

    Transplanting Hepatitis C Infected Organs Into Uninfected Recipients: A Pharmacy Perspective

    M. L. Holt, A. James, K. Gutierrez, T. Sparkman, J. Banbury, D. Jones

    University of Alabama at Birmingham Hospital, Birmingham, AL

    *Purpose: Due to direct acting antivirals (DAAs), hepatitis C virus (HCV) positive patients are now resources for organ transplantation in HCV negative recipients. Our institution…
  • 2021 American Transplant Congress

    The Use of Hcv Nat+ Organs in Hcv Negative Recipients with On-site Specialty Pharmacy Services: A Win for the Patient, the Transplant Center, and Society?

    M. Person, N. Patel, W. Simerlein, H. Meadows, D. DuBay, D. Taber

    Medical University of South Carolina, Charleston, SC

    *Purpose: Use of HCV AB positive organs (HCV AB+) with active viremia (NAT+) relies on appropriate and timely use of direct acting antiviral therapies (DAA).…
  • 2020 American Transplant Congress

    Efficacy of Generic Sofosbuvir and Branded Daclatasvir Compared to Sofosbuvir and Ledipasvir Combination in the Treatment of Genotype 4 Hepatitis C Virus

    H. Joharji, D. Alkortas, A. Ajlan, E. Devol, M. Ahmed, F. Aba Al-Khail, H. Elsiesy, M. Alsebayel, H. Alashgar, M. Alquaiz, W. Alhamoudi, A. Almoshishir, A. Aljedai

    King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: Genotype 4 HCV is the most common genotype in Saudi Arabia and the Middle East. Management of HCV has shifted in the last few…
  • 2020 American Transplant Congress

    Glecaprevir-Pibrentasvir Effect on Tacrolimus Troughs in Abdominal Transplant Recipients

    M. Chunduru, K. Schnelle, H. Winters, O. Witkowsky, L. Von Stein

    The Ohio State Wexner Medical Center, Columbus, OH

    *Purpose: Glecaprevir-pibrentasvir (GP) is one of several pangenotypic therapies available for the treatment of hepatitis C. Historical use of ritonavir based hepatitis C therapies increased…
  • 2020 American Transplant Congress

    Association between Ezetimibe Usage and Hepatitis C RNA Levels in Uninfected Kidney Transplant Recipients Who Received Hepatitis C Infected Kidneys

    A. Azhar, M. Yazawa, M. Talwar, V. Balaraman, A. Bhalla, U. A. Agbim, B. Maliakkal, J. P. Kothadia, S. Nair, J. D. Eason, M. Z. Molnar

    James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN

    *Purpose: Our previous data showed that transplantation of kidneys from hepatitis C virus (HCV) infected donors to HCV negative recipients achieved excellent short-term graft function,…
  • 2020 American Transplant Congress

    Single Center Experience of Valganciclovir and Adjunctive CMV IVIG for the Treatment of CMV Infection in Lung Transplant Recipients

    A. A. Fernandez1, N. Sinha2, M. Loebe2, J. Glaze2, S. Manickavel2, M. Fernandez2, T. Pastrana2, J. Simkins3, J. Camargo3, M. I. Morris3, L. Abbo3, Y. Natori3

    1Infectious Disease, University of Miami Jackson Memorial Hospital, Miami, FL, 2University of Miami Jackson Memorial Hospital, Miami, FL, 3Transplant Infectious Disease, University of Miami Jackson Memorial Hospital, Miami, FL

    *Purpose: Cytomegalovirus(CMV) infection happens commonly and causes significant morbidity in lung transplant (LTx) recipients. The use of CMV hyperimmune globulin (CMVIg) as an adjunctive treatment…
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