ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Viral therapy"

  • 2016 American Transplant Congress

    Incidence of Viral Infections in HLA-Sensitized Patients (HS Pts) Desensitized with IVIG + Rituximab (DES) Compared to Non-HS Pts Receiving Standard Immunosuppression.

    S. Jordan, J. Choi, B. Shin, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, M. Toyoda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: HS pts (PRA>50%, DSA+ at transplant) who are transplanted without DES represent a significant risk for antibody-mediated rejection. Prior to transplantation, HS pts require…
  • 2016 American Transplant Congress

    Characterization of Resistant Cytomegalovirus in Lung Transplant Recipients in the Modern Era.

    S. Hammad, L. Shah, M. Restivo, H. Robbins, J. Scheffert.

    NewYork-Presbyterian Hospital, New York, NY.

    Cytomegalovirus (CMV) remains a major cause of morbidity and mortality in lung transplant recipients (LTR) and the emergence of resistant CMV (rCMV) has increased. The…
  • 2016 American Transplant Congress

    EBV Sero-Positivity Does Not Reduce the Risk for EBV Viremia and/or Post-Transplant Lymphoproliferative Disorder (PTLD) in Patients (Pts) Receiving Belatacept (CTLA4Ig).

    J. Choi, B. Shin, J. Kahwaji, S. Ge, D. Thomas, A. Vo, O. Galera, R. Villicana, A. Peng, S. Jordan, M. Toyoda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: CTLA4Ig is a novel immunosuppressive (IS) which acts through costimulatory blockade of T-cells and obviates the need for calcineurin inhibitor-based IS (CNI-IS). Despite benefits…
  • 2016 American Transplant Congress

    Reduced-Dose Cidofovir (CID) and CMV-Hyperimmune Globulin (CMVIg) for Ganciclovir-Resistant Cytomegalovirus: Effective and Kidney Friendly.

    S. Patel, S. Kuten, J. Snyder, R. Knight, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    Ganciclovir resistant (GR) CMV is associated with an aggressive disease course and substantial morbidity. Furthermore, treatment options such as foscarnet and cidofovir are incredibly nephrotoxic.…
  • 2016 American Transplant Congress

    Prophylactic Anti-Virus Therapy, Is It Necessary to Occult Hepatitis B Virus Carriers with HBsAg(-) and HBcAb(+) After Kidney Transplantation?

    G. Chen, C. Wang, L. Chen, J. Qiu, C. Wang.

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Background Hepatitis B virus(HBV) infection is common among uremia patients in China. Many patients received kidney transplantation are occult HBV carriers with HBsAg(-) and HBcAb(+)…
  • 2016 American Transplant Congress

    Descriptive Epidemiology and Trends of Community Parenteral Antimicrobial Therapy Utilization Among Solid Organ Transplant Recipients at a High Volume Transplant Center 2008 to 2014.

    S. Mawhorter, N. Shrestha.

    Infectious Diseases, Cleveland Clinic, Cleveland, OH.

    INTRODUCTION: Solid organ transplant (SOT) recipients may benefit from community-based parenteral anti-infective therapy (CoPAT). Limited data are available. CoPAT may help reduce LOS. As a…
  • 2016 American Transplant Congress

    Is SVR Associated with Improved Hepatic Function in Hepatitis C Gen 1 Pts with Cirrhosis 1 Year After Completing Treatment with Sofosbuvir + Simeprevir +/- Ribavirin?

    A. Modi,1 J. Hermann,1 H. Nazario,2 S. Gonzalez,1 J. Gripshover,3 M. Gautam,1 J. Weinstein,2 D. Potosky,3 M. Barnes,2 A. Habib,2 P. Mantry,2 J. Trotter.1

    1Liver Consultants of Texas, Dallas-Fort Worth, TX; 2Liver Institute Methodist, Dallas, TX; 3University of Maryland, Baltimore, MD.

    Background: Combination antiviral therapy involving Sofosbuvir (SOF) & Simeprevir (SIM) +/- Ribavirin (RBV) is a relatively safe & effective Tx option in pts with gen…
  • 2016 American Transplant Congress

    Safety and Efficacy of Ledipasvir/Sofosbuvir (LS) with or without Ribavirin (RBV) for Treatment of Recurrent Hepatitis C Infection Post-Liver Transplant.

    K. Gutierrez, J. Scheuermann, I. Goldvarg, S. Joshi, G. Tyson, N. Bzowej, N. Girgrah, S. Anders, G. Loss, G. Therapondos.

    Mulit-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA.

    Background: Hepatitis C (HCV) is the most common indication for liver transplant in the United States representing more than 40% of all recipients. Availability of…
  • 2016 American Transplant Congress

    Potential Biomarkers and Treatment for BK Virus Associated Nephropathy.

    M. Borkar,1 V. Srivastava,2 R. Cunnington,1 T. Sharma,1 L. Tibbles.1

    1Faculty of Mediicne, University of Calgary, Calgary, AB, Canada; 2CSIR-Indian Institute of Toxicology Research, Lucknow, Uttar Pradesh, India.

    Background: BK polyomavirus assoiciated nephropathy (BKVAN) is one of the major complications in renal transplants, and is associated with significant fibrosis It is important to…
  • 2015 American Transplant Congress

    Safety and Efficacy of Pegylated Interferon and Ribavirin for Chronic Hepatitis C Following Renal Transplantation

    G. Chen, L. Zhu, S. Chen, X. Wang, Z. Lin.

    Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.

    Objective We sought to investigate the safety and efficacy of pegylated Interferon (PEG-IFN) and ribavirin for chronic hepatitis C (HCV) following renal transplantation.Methods Ten adult…
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