ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Viral therapy"

  • 2022 American Transplant Congress

    Management of Hepatitis B Positive Donors in Liver Transplant

    M. Tilley1, T. A. Sparkman2, K. Gutierrez2

    1Pharmacy, UAB, Birmingham, AL, 2UAB, Birmingham, AL

    *Purpose: In an effort to expand the pool of solid organ transplant donors, patients with end stage liver disease may receive an organ from a…
  • 2022 American Transplant Congress

    Transplantation of Hepatitis C Viremic Donor Organs to Hepatitis C Nonviremic Recipients: A Retrospective Review

    M. Leick, M. Blaha, M. Henry

    Nebraska Medicine, Omaha, NE

    *Purpose: The advent of combination direct-acting antiviral (DAA) agents has improved the ability to treat hepatitis C virus (HCV) infections. As a result, utilization of…
  • 2022 American Transplant Congress

    Hepatitis C Positive Kidney Transplant Into Hepatitis C Negative Recipients

    R. Savilla1, A. Ricketts1, S. A. Deslich2, S. Vaishnav1, J. B. Africa1, S. Nagaraju1

    1Renal Transplant, Charleston Area Medical Center, Charleston, WV, 2Research Associate Senior, Health Services & Outcomes Rsc, Charleston Area Medical Center, Charleston, WV

    *Purpose: Kidney transplantation is the treatment of choice in end stage renal disease (ESRD). In 2018, 5% to 8% of eligible adults died while on…
  • 2022 American Transplant Congress

    Use of Kidneys from Hepatitis C Nat Positive Donors for Uninfected Recipients: Early Results from a Rural Appalachian Kidney Transplant Program

    B. Gillis1, F. Afridi1, R. Lopez1, V. Chaudhary1, D. Kannabhiran1, C. Fagella1, R. Zomak1, K. Meyer1, M. Thornberg1, L. Biondi2

    1Department of Surgery, West Virginia University, Morgantown, WV, 2Department of Surgery, West Virginia University, Morgantown, WV, WV

    *Purpose: Increasing mismatch between kidneys available for transplant and the number of patients on the transplant wait list has led to research into novel sources…
  • 2022 American Transplant Congress

    A Randomized Phase 2 Study Of Mau868 Vs Placebo To Treat Bk Viremia In Kidney Transplant Recipients

    S. Jordan1, A. P. Limaye2, B. Fischbach3, P. Sood4, S. Collette5, L. Gasink6, M. W. Fordyce7, C. J. Lin7, M. Hodges6, D. C. Brennan8

    1Cedars-Sinai Medical Center, Los Angeles, CA, 2University of Washington, Seattle, WA, 3Dallas Nephrology Associates, Inc, Dallas, TX, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada, 6previous employee/consultant for Amplyx Pharmaceuticals, San Diego, CA, 7Vera Therapeutics, Inc, Brisbane, CA, 8Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: To assess the safety and efficacy of MAU868, a BK virus-specific monoclonal antibody, in adult kidney transplant recipients with BK viremia.*Methods: This is a…
  • 2022 American Transplant Congress

    Risk for Loss of Hepatitis B Surface Antibody or Hepatitis B Reactivation in Kidney Transplant Recipients Receiving Lymphocyte Depleting Induction

    K. Paplaczyk1, C. Kane1, M. Kapugi1, K. Lang1, K. Cunningham1, C. D'Agostino1, J. Boike2

    1Pharmacy, Northwestern Memorial Hospital, Chicago, IL, 2Transplant Hepatology, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Although used in over 60% of kidney transplant recipients, the impact of lymphocyte depleting induction on hepatitis B surface antibody (HBsAb) and hepatitis B…
  • 2022 American Transplant Congress

    Clinical Features and Outcomes of Hospitalized Solid Organ Transplant and Hematopoietic Stem Cell Recipients with Sars-CoV-2 Infection in the Midwestern United States: A Multi-Center Retrospective Cohort Study

    S. Tanna1, D. Florescu2, A. Majeed3, J. Banzon3, S. Waller4, A. Eid4, N. Barros Baertl5, D. Friedman6, K. Mullane7, M. Ison8

    1Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 2University of Nebraska Medical Center, Omaha, NE, 3Cleveland Clinic, Cleveland, OH, 4University of Kansas Medical Center, Overland Park, KS, 5Infectious Diseases, Indiana University, Indianapolis, IN, 6Infectious Diseases, University of Chicago, Chicago, IL, 7University of Chicago, Chicago, IL, 8Northwestern University Comprehensive Transplant Center, Chicago, IL

    *Purpose: Immunocompromised hosts are at risk for severe complications or death from SARS-CoV-2 infection. Few studies describe the clinical features, outcomes and treatment strategies in…
  • 2022 American Transplant Congress

    Letermovir for Prophylaxis of Cytomegalovirus After Solid Organ Transplantation: A Single-Center, Observational Study

    T. N. Bullard1, C. A. Moore2, J. Dasigi2, L. M. Sacha2, C. A. Iasella3, K. A. Shimko2, E. K. McCreary4, F. P. Silveira4

    1Massachusetts General Hospital, Boston, MA, 2UPMC, Pittsburgh, PA, 3Univ of Pittsburgh, Pittsburgh, PA, 4Univ of Pittsburgh and UPMC, Pittsburgh, PA

    *Purpose: Cytomegalovirus (CMV) infections cause significant complications post-transplant; however, prophylactic medications are often limited by toxicities. Letermovir is a novel terminase inhibitor specific to CMV…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Valacyclovir versus Valganciclovir for CMV Prophylaxis: A Randomized Controlled Trial

    P. S. Verghese1, A. Matas2, S. Chinnakotla2, M. Evans3, H. Balfour Jr4

    1Univ of Minnesota Pediatric Nephrology, Minneapolis, MN, 2Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Biostatistics, University of Minnesota, Minneapolis, MN, 4Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: Valganciclovir (valG) is an effective CMV prophylactic agent post-kidney transplant (KTx) with significant side effects. Valacyclovir (valA) may be effective for CMV prophylaxis with…
  • 2022 American Transplant Congress

    Use of Viral Specific T Cell Therapy in Solid Organ Transplant Recipients – A Single Center Experience

    G. McGraw1, N. Patel2, K. Patel1, S. Bumb3, A. Govil4, M. Anand1

    1University of Cincinnati, Cincinnati, OH, 2Nephrology, University of Cincinnati, Cincinnati, OH, 3Nephrology, Internal Medicine, University of Cincinnati Medical Center, Blue Ash, OH, 4Univ of Cincinnati, Cincinnati, OH

    *Purpose: Viral infections such as BK virus (BKV), cytomegalovirus (CMV) and adenovirus after kidney transplantation negatively impact outcomes in solid organ transplant (SOT) recipients despite…
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