Articles tagged "Ventricular assist devices"

2019 American Transplant Congress
Natural Antibodies and Left Ventricular Assist Device Complications
S. B. See¹, A. Pinsino², R. Shihab¹, N. Kunimune¹, D. Onat², E. Hittesdorf³, A. R. Garan², V. K. Topkara², Y. Naka⁴, H. Takayama⁴, K. Takeda⁴, P. Colombo², M. Yuzefpolskaya², G. Wagener³, E. Zorn¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Division of Cardiology, Columbia University, New York, NY, ³Department of Anesthesiology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Left ventricular assist devices (LVAD) are used as a bridge to heart transplantation or destination therapy for advanced heart failure. For all its benefits,…
2019 American Transplant Congress
Could Intravenous Iron Strengthen The Chances Of Heart Transplantation For Patients With Left Ventricular Assist Devices?
A. Mardis¹, C. Mardis², J. Barham³, A. Poole³, S. Branham³, R. Napier⁴, J. Martin³, P. McCann⁴
¹Department of Pharmacy, Palmetto Health, Columbia, SC, ²Clinical Pharmacy and Outcomes Sciences, University of South Carolina, Columbia, SC, ³Cardiothoracic Surgery, Palmetto Health, Columbia, SC, ⁴Cardiology, Palmetto Health, Columbia, SC
*Purpose: Iron deficiency anemia (IDA) is prevalent in patients supported by left ventricular assist devices (LVADs), is associated with functional limitations, and often warrants blood…
2019 American Transplant Congress
Utility of Gallium-67 Single Photon Emission Computed Tomography in the Evaluation of Left Ventricular Assist Device Infections
F. Parkar¹, A. Tlamsa², J. Nistico², V. A. Muggia², G. Y. Minamoto², U. Jorde³, D. J. Goldstein³, R. Moadel¹, Y. A. Puius²
¹Division of Nuclear Medicine, Montefiore Medical Center, Bronx, NY, ²Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, ³Department of Cardiothoracic and Vascular Surgery, Montefiore Medical Center, Bronx, NY
*Purpose: We routinely use gallium-67 single photon emission computed tomography (67Ga-SPECT-CT) to determine the presence and extent of left ventricular assist device (LVAD) infections. The…
2019 American Transplant Congress
Efficacy of Long-Acting Octreotide in Left Ventricular Assist Device Patients with Recurrent Gastrointestinal Bleeding
T. Wilson¹, D. Baran², J. Herre², C. Cameron¹, W. Old³, G. Zeevi², C. Barreiro⁴, C. Kemp⁴, J. Philpott⁴, A. Ingemi⁵
¹Pharmacy Department, Sentara Norfolk General Hospital, Norfolk, VA, ²Advanced Heart Failure Department, Sentara Norfolk General Hospital, Norfolk, VA, ³Bayview Cardiovascular Associates, Norfolk, VA, ⁴Division of Cardiothoracic Surgery, Sentara Norfolk General Hospital, Norfolk, VA, ⁵Department of Pharmacy, Sentara Norfolk General Hospital, Norfolk, VA
*Purpose: Continuous flow ventricular assist device (VAD) patients have a high risk of recurrent gastrointestinal bleeding, often leading to readmission and morbidity. Intramuscular long-acting octreotide…
2018 American Transplant Congress
Impact of Infections on Patients with Left Ventricle Assist Devices(LVAD): Allo-Sensitization and Heart Transplantation
C. Buto-Colletti, P. Kimball, K. Shah, M. Quader.
Virginia Commonwealth University, Richmond.
Background: The impact of post-LVAD infections on allosensitization and heart transplantation (HT) is unknown. High levels of panel reactive antibodies (PRA) preclude HT but the…
2018 American Transplant Congress
Single vs. Multi-Drug Antibiotic Prophylaxis for Continuous-Flow Left Ventricular Assist Device Implantation: A Systematic Review and Meta-Analysis
S. Patel,¹ J. Choi,¹ E. Moncho Escrivà,² S. Rizvi,¹ L. Samuels,¹ J. Luc,³ R. Morris,¹ H. Massey,¹ V. Tchantchaleishvili,¹ N. Aburjania.⁴
¹Division of Cardiac Surgery, Thomas Jefferson University, Philadelphia, PA; ²University of Granada, Granada, Spain; ³University of Alberta, Edmonton, AB, Canada; ⁴Division of Infectious Diseases, Thomas Jefferson University, Philadelphia, PA.
Purpose: Despite the fact that infection remains a major complication of continuous-flow left ventricular assist device (CF-LVAD) therapy, an optimal antimicrobial surgical infection prophylaxis (SIP)…
2018 American Transplant Congress
Institution-Based, Pharmacist-Managed Anticoagulation in Patients with a Left Ventricular Assist Device
T. Bibb,¹ L. Halder,¹ D. McDanel,¹ A. Briasoulis,² P. Alvarez,² K. Horner,¹ J. Bhama,³ S. Larson.³
¹Department of Pharmaceutical Care, University of Iowa Hospitals and Clinics, Iowa City, IA; ²Division of Cardiovascular Medicine, Department of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA; ³Division of Cardiothoracic Surgery, Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA.
Long-term anticoagulation with warfarin is required for patients with left ventricular assist devices (LVADs). There is limited data of time in therapeutic range (TTR) in…
2017 American Transplant Congress
Antibodies to Angiotensin Type II Receptor I Are Associated with Primary Graft Dysfunction After Orthotopic Heart Transplant in Patients with Ventricular Assist Device as Bridge to Transplant.
M. Hickey,¹ E. DePasquale,² S. Shah,³ D. Vucicevic,² J. Zhang,¹ N. Valenzuela,¹ M. Deng,² E. Reed.¹
¹UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; ²UCLA Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA; ³UCLA David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA
Primary graft dysfunction (PGD) following orthotopic heart transplant (OHT) is one of the leading causes of posttransplant mortality. We hypothesized that antibody to angiotensin type…
2016 American Transplant Congress
Clostridium difficile Infection in Patients with a Continuous Flow, Durable Left Ventricular Assist Device.
J. Glick Frasiolas, I. Li, H. Kim, D. Tsapepas.
NewYork-Presbyterian Hospital, Columbia University, New York.
Clostridium difficile infection (CDI) increases morbidity and mortality in hospitalized patients. Patients with a ventricular assist device (VAD) are exposed to known risk factors for…
2016 American Transplant Congress
Serial Peripheral Blood Mononuclear Cell Expression Profiling Reveals Inflammatory Genomic Storm Following Mechanical Circulatory Support Surgery.
G. Godoy,¹ G. Bondar,¹ A. Esmaeili,¹ E. Arellano,¹ E. Chang,¹ M. Bakir,¹ J. Chittoor,¹ R. Togashi,¹ N. Fazli,¹ C. Starling,¹ E. Oh,¹ S. Toluie,¹ Z. Yang,² D. Tran,¹ M. Cadeiras,¹ N. Wisniewski,¹ M. Kwon,¹ J. Schaenman,¹ Y. Korin,¹ M. Rosetti,¹ E. Reed,¹ M. Deng.¹
¹University of California, Los Angeles, Los Angeles, CA; ²Shanxi Medical University First Hospital, Taiyuan, Shanxi, China.
Introduction: The main cause of death in patients with Advanced Heart Failure (AdHF) is the Multi-Organ Dysfunction (MOD) Syndrome. Immune system aberrancy after Mechanical Circulatory…