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Articles tagged "Ventricular assist devices"

  • 2020 American Transplant Congress

    Possible Mechanism of Sensitization against Angiotensin Type II Receptor after LVAD Implantation

    P. Kimball1, V. Chau2, F. McDougan1, M. Flattery2, K. Shah2

    1Surgery, VCUHS, Richmond, VA, 2Cardiology, VCUHS, Richmond, VA

    *Purpose: Detection of antibody (Ab) against angiotensin-II receptor (AT1R) following VAD implantation portends poorer outcomes for heart transplantation (HT). However, the cause of this sensitization…
  • 2020 American Transplant Congress

    Utilization of Mechanical Circulatory Support Devices and Impact on Outcomes in the New Heart Allocation System: An Analysis of the UNOS Registry

    L. K. Truby1, M. Farr2, E. M. DeFilippis3, K. Takeda3, V. K. Topkara3

    1Duke University Medical Center, Durham, NC, 2Columbia University Irving Medical Center, New York City, NY, 3Columbia University Irving Medical Center, New York, NY

    *Purpose: In October 2018, a new heart transplantation allocation system was put into effect with the intent of better stratifying the most medically urgent candidates,…
  • 2020 American Transplant Congress

    Comparison of Six-Month Outcomes in Patients Bridged to Heart Transplantation with Percutaneous Temporary Circulatory Support Before and after the UNOS Allocation System Change

    J. Nattiv1, G. S. Liu1, P. Banankhah1, J. Sussex1, P. Genyk1, J. Li1, D. Vucicevic2, R. S. Chand3, K. Pandya1, J. Rahman1, A. M. Wolfson4, A. S. Vaidya1, E. DePasquale1

    1Keck Hospital of USC, Los Angeles, CA, 2Newark Beth Israel Medical Center, Newark, NJ, 3Harbor UCLA Medical Center, Los Angeles, CA, 4University of Arizona Sarver Heart Center, Tucson, AZ

    *Purpose: We report the trends in utilization and outcomes of percutaneous temporary circulatory support (TCS) in the forms of Impella or TandemHeart as a bridge…
  • 2020 American Transplant Congress

    The Association between Preoperative Hemodynamics and Right Ventricular Failure Following Implantation of Left Ventricular Assist Device

    D. Bhakta1, A. Alam2, J. S. van Zyl2, H. Zafar2, A. Aasim2, D. M. Meyer2, J. Felius2, S. Hall2, D. Wencker2

    1Texas A&M University College of Medicine, Dallas, TX, 2Baylor University Medical Center, Dallas, TX

    *Purpose: Right ventricular failure (RVF) following left ventricular assist device (LVAD) implantation is a common complication and associated with increased mortality. Clinical predictors contributing to…
  • 2020 American Transplant Congress

    Natural Antibodies and Left Ventricular Assist Device Complications

    S. B. See1, D. Onat2, E. Hittesdorf3, F. McDougan4, M. Yuzefpolskaya2, V. K. Topkara2, Y. Naka5, H. Takayama5, K. Takeda5, G. Milligan6, D. Wencker6, S. Hall6, M. Askar6, P. Kimball4, G. Wagener3, P. C. Colombo2, E. Zorn1

    1Columbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY, 2Department of Medicine, Columbia University Irving Medical Center, New York, NY, 3Department of Anesthesiology, Columbia University Irving Medical Center, New York, NY, 4Department of Transplant Surgery, Virginia Commonwealth University, Richmond, VA, 5Department of Surgery, Columbia University Irving Medical Center, New York, NY, 6Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX

    *Purpose: Left ventricular assist device (LVAD) implantation is followed by a sharp increase in serum levels of IgG natural antibodies (Nabs) recognizing oxidation-specific epitopes (OSE)…
  • 2019 American Transplant Congress

    Caregiving before Thoracic Transplantation–A Qualitative Inquiry

    C. C. Kennedy1, J. Ridgeway1, E. Stevens1, J. Kirsch2, K. Carroll1, J. Griffin1, R. Benzo1

    1Mayo Clinic, Rochester, MN, 2University of Florida-Gainesville, Gainesville, FL

    *Purpose: Although post-transplant caregiver (CG) support is a prerequisite for transplant listing, research shows CG outcomes including stress and social functioning may be worse during…
  • 2019 American Transplant Congress

    Incidence and Risk of Allograft Rejection after Cardiac Transplantation in Left Ventricular Assist Device Patients

    R. C. Patel1, L. B. Cooper2, S. D. Barnett2, R. T. Cole2, M. A. Psotka2, A. Cochrane2, S. Sinha2, L. J. Bogar2, S. S. Desai2, P. Shah2

    1Virginia Commonwealth University School of Medicine, Inova Fairfax Hospital, Falls Church, VA, 2Department of Heart Failure and Transplant, Inova Heart and Vascular Institute, Falls Church, VA

    *Purpose: Left ventricular assist devices (LVAD) are made of biomaterials that have been shown to cause allosensitization. Single center studies have suggested that patients bridged…
  • 2019 American Transplant Congress

    Low Frequency Of Canonical Human Leukocyte Antigen Alloimmunization In Heart Transplantation Candidates With Ventricular Assist Devices

    G. K. Mahowald1, S. L. Saidman1, G. Lewis2, V. Pattanayak1

    1Pathology, Massachusetts General Hospital, Boston, MA, 2Cardiology, Massachusetts General Hospital, Boston, MA

    *Purpose: Screening for anti-HLA antibodies in heart transplantation candidates is complicated by transfusions as well as by the presence of ventricular assist devices (VADs), which…
  • 2019 American Transplant Congress

    Natural Antibodies and Left Ventricular Assist Device Complications

    S. B. See1, A. Pinsino2, R. Shihab1, N. Kunimune1, D. Onat2, E. Hittesdorf3, A. R. Garan2, V. K. Topkara2, Y. Naka4, H. Takayama4, K. Takeda4, P. Colombo2, M. Yuzefpolskaya2, G. Wagener3, E. Zorn1

    1Columbia Center for Translational Immunology, Columbia University, New York, NY, 2Division of Cardiology, Columbia University, New York, NY, 3Department of Anesthesiology, Columbia University, New York, NY, 4Department of Surgery, Columbia University, New York, NY

    *Purpose: Left ventricular assist devices (LVAD) are used as a bridge to heart transplantation or destination therapy for advanced heart failure. For all its benefits,…
  • 2019 American Transplant Congress

    Could Intravenous Iron Strengthen The Chances Of Heart Transplantation For Patients With Left Ventricular Assist Devices?

    A. Mardis1, C. Mardis2, J. Barham3, A. Poole3, S. Branham3, R. Napier4, J. Martin3, P. McCann4

    1Department of Pharmacy, Palmetto Health, Columbia, SC, 2Clinical Pharmacy and Outcomes Sciences, University of South Carolina, Columbia, SC, 3Cardiothoracic Surgery, Palmetto Health, Columbia, SC, 4Cardiology, Palmetto Health, Columbia, SC

    *Purpose: Iron deficiency anemia (IDA) is prevalent in patients supported by left ventricular assist devices (LVADs), is associated with functional limitations, and often warrants blood…
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