Articles tagged "Ventricular assist devices"

2018 American Transplant Congress
Impact of Infections on Patients with Left Ventricle Assist Devices(LVAD): Allo-Sensitization and Heart Transplantation
C. Buto-Colletti, P. Kimball, K. Shah, M. Quader.
Virginia Commonwealth University, Richmond.
Background: The impact of post-LVAD infections on allosensitization and heart transplantation (HT) is unknown. High levels of panel reactive antibodies (PRA) preclude HT but the…
2018 American Transplant Congress
Single vs. Multi-Drug Antibiotic Prophylaxis for Continuous-Flow Left Ventricular Assist Device Implantation: A Systematic Review and Meta-Analysis
S. Patel,¹ J. Choi,¹ E. Moncho Escrivà,² S. Rizvi,¹ L. Samuels,¹ J. Luc,³ R. Morris,¹ H. Massey,¹ V. Tchantchaleishvili,¹ N. Aburjania.⁴
¹Division of Cardiac Surgery, Thomas Jefferson University, Philadelphia, PA; ²University of Granada, Granada, Spain; ³University of Alberta, Edmonton, AB, Canada; ⁴Division of Infectious Diseases, Thomas Jefferson University, Philadelphia, PA.
Purpose: Despite the fact that infection remains a major complication of continuous-flow left ventricular assist device (CF-LVAD) therapy, an optimal antimicrobial surgical infection prophylaxis (SIP)…
2018 American Transplant Congress
Institution-Based, Pharmacist-Managed Anticoagulation in Patients with a Left Ventricular Assist Device
T. Bibb,¹ L. Halder,¹ D. McDanel,¹ A. Briasoulis,² P. Alvarez,² K. Horner,¹ J. Bhama,³ S. Larson.³
¹Department of Pharmaceutical Care, University of Iowa Hospitals and Clinics, Iowa City, IA; ²Division of Cardiovascular Medicine, Department of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA; ³Division of Cardiothoracic Surgery, Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA.
Long-term anticoagulation with warfarin is required for patients with left ventricular assist devices (LVADs). There is limited data of time in therapeutic range (TTR) in…
2017 American Transplant Congress
Antibodies to Angiotensin Type II Receptor I Are Associated with Primary Graft Dysfunction After Orthotopic Heart Transplant in Patients with Ventricular Assist Device as Bridge to Transplant.
M. Hickey,¹ E. DePasquale,² S. Shah,³ D. Vucicevic,² J. Zhang,¹ N. Valenzuela,¹ M. Deng,² E. Reed.¹
¹UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; ²UCLA Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA; ³UCLA David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA
Primary graft dysfunction (PGD) following orthotopic heart transplant (OHT) is one of the leading causes of posttransplant mortality. We hypothesized that antibody to angiotensin type…
2016 American Transplant Congress
Serial Peripheral Blood Mononuclear Cell Expression Profiling Reveals Inflammatory Genomic Storm Following Mechanical Circulatory Support Surgery.
G. Godoy,¹ G. Bondar,¹ A. Esmaeili,¹ E. Arellano,¹ E. Chang,¹ M. Bakir,¹ J. Chittoor,¹ R. Togashi,¹ N. Fazli,¹ C. Starling,¹ E. Oh,¹ S. Toluie,¹ Z. Yang,² D. Tran,¹ M. Cadeiras,¹ N. Wisniewski,¹ M. Kwon,¹ J. Schaenman,¹ Y. Korin,¹ M. Rosetti,¹ E. Reed,¹ M. Deng.¹
¹University of California, Los Angeles, Los Angeles, CA; ²Shanxi Medical University First Hospital, Taiyuan, Shanxi, China.
Introduction: The main cause of death in patients with Advanced Heart Failure (AdHF) is the Multi-Organ Dysfunction (MOD) Syndrome. Immune system aberrancy after Mechanical Circulatory…
2016 American Transplant Congress
Clostridium difficile Infection in Patients with a Continuous Flow, Durable Left Ventricular Assist Device.
J. Glick Frasiolas, I. Li, H. Kim, D. Tsapepas.
NewYork-Presbyterian Hospital, Columbia University, New York.
Clostridium difficile infection (CDI) increases morbidity and mortality in hospitalized patients. Patients with a ventricular assist device (VAD) are exposed to known risk factors for…
2015 American Transplant Congress
Assessment of Hospital Readmissions After Mechanical Circulatory Support
F. Arabia, M. Kittleson, L. Czer, J. Hajj, E. Passano, F. Liou, S. Siddiqui, D. Chang, J. Kobashigawa, J. Moriguchi.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Hospital readmission is viewed as one of the benchmarks for success following mechanical circulatory support (MCS) placement. It is not clear whether there is…
2015 American Transplant Congress
Type of Caregiver and Outcome After Mechanical Circulatory Support Placement
H. Henry, F. Arabia, M. Kittleson, L. Czer, E. Passano, J. Yabuno, S. Siddiqui, E. Antifantis, D. Chang, J. Kobashigawa.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Caregiver support following mechanical circulatory support (MCS) implantation is key to good outcomes. The caregiver support can come from a spouse, parent, other relative,…
2015 American Transplant Congress
Left Ventricular Assist Device–Associated Allosensitization — Clinical Implications
B.-S. Ko, C. Willis, S. Drakos, D. Hurst, A. Kfoury, G. Snow, J. Delgado, E. Hammond, C. Selzman, R. Alharethi, S. McKellar, J. Nativi-Nicolau, E. Gilbert, P. Revelo, D. Miller, B. Reid, J. Fang, D. Eckles, J. Stehlik.
U.T.A.H. Cardiac Transplant Program, Salt Lake City, UT.
Purpose: Allosensitization has been recognized as a prognostic marker of worse outcome after transplant. It is unclear, however, whether sensitization events that take place shortly…
2015 American Transplant Congress
Increased Frequency of Terminally Differentiated and Exhausted CD8+ T Cells Is Associated With Adverse Clinical Outcome After Mechanical Circulatory Support Device Implantation
J. Schaenman,¹ Y. Korin,² T. Sidwell,² G. Sunga,² G. Bondar,³ N. Wisniewski,³ M. Kwon,⁴ M. Cadeiras,³ M. Deng,³ E. Reed.²
¹Medicine/Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA; ²Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA; ³Medicine/Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA; ⁴Cardiothoracic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Clinical outcomes vary after mechanical circulatory support device (MCSD) implantation, with some patients developing multi organ system dysfunction (MOD), sometimes leading to death. We hypothesized…