Articles tagged "Ventricular assist devices"

2022 American Transplant Congress
Post Heart Transplant Outcomes of Desensitized Durable Mechanical Circulatory Support Patients
J. Youn¹, D. Kim², J. Choi², K. Kim¹, I. Kim³, E. Kransdorf⁴, D. Chang⁴, M. Kittleson⁴, J. Patel⁴, R. Cole⁴, J. Moriguchi⁴, D. Ramzy⁵, F. Esmailian⁵, J. A. Kobashigawa⁴
¹Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ³Keimyung University Dongsan Hospital, Daegu, Korea, Republic of, ⁴Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Department of Cardiothoracic Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Desensitization therapy (DST) is considered to increase the chances of a negative crossmatch, to expand the number of suitable donors, and to improve post-transplant…
2022 American Transplant Congress
Outcome of Heart Transplantation After Pseudomonas Left Ventricular Assist Device Infection
L. Thirunavukarasu Murugan¹, C. Koval², J. Banzon³
¹Infectious Disease, Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic Foundation, Cleveland, OH, ³Cleveland Clinic, Cleveland, OH
*Purpose: Pseudomonas aeruginosa (PA) is the most common gram-negative bacteria to cause left ventricular assist device (LVAD) infection. Management is difficult given limited oral antibiotic…
2020 American Transplant Congress
The Association between Preoperative Hemodynamics and Right Ventricular Failure Following Implantation of Left Ventricular Assist Device
D. Bhakta¹, A. Alam², J. S. van Zyl², H. Zafar², A. Aasim², D. M. Meyer², J. Felius², S. Hall², D. Wencker²
¹Texas A&M University College of Medicine, Dallas, TX, ²Baylor University Medical Center, Dallas, TX
*Purpose: Right ventricular failure (RVF) following left ventricular assist device (LVAD) implantation is a common complication and associated with increased mortality. Clinical predictors contributing to…
2020 American Transplant Congress
Natural Antibodies and Left Ventricular Assist Device Complications
S. B. See¹, D. Onat², E. Hittesdorf³, F. McDougan⁴, M. Yuzefpolskaya², V. K. Topkara², Y. Naka⁵, H. Takayama⁵, K. Takeda⁵, G. Milligan⁶, D. Wencker⁶, S. Hall⁶, M. Askar⁶, P. Kimball⁴, G. Wagener³, P. C. Colombo², E. Zorn¹
¹Columbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY, ²Department of Medicine, Columbia University Irving Medical Center, New York, NY, ³Department of Anesthesiology, Columbia University Irving Medical Center, New York, NY, ⁴Department of Transplant Surgery, Virginia Commonwealth University, Richmond, VA, ⁵Department of Surgery, Columbia University Irving Medical Center, New York, NY, ⁶Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX
*Purpose: Left ventricular assist device (LVAD) implantation is followed by a sharp increase in serum levels of IgG natural antibodies (Nabs) recognizing oxidation-specific epitopes (OSE)…
2020 American Transplant Congress
Possible Mechanism of Sensitization against Angiotensin Type II Receptor after LVAD Implantation
P. Kimball¹, V. Chau², F. McDougan¹, M. Flattery², K. Shah²
¹Surgery, VCUHS, Richmond, VA, ²Cardiology, VCUHS, Richmond, VA
*Purpose: Detection of antibody (Ab) against angiotensin-II receptor (AT1R) following VAD implantation portends poorer outcomes for heart transplantation (HT). However, the cause of this sensitization…
2020 American Transplant Congress
Utilization of Mechanical Circulatory Support Devices and Impact on Outcomes in the New Heart Allocation System: An Analysis of the UNOS Registry
L. K. Truby¹, M. Farr², E. M. DeFilippis³, K. Takeda³, V. K. Topkara³
¹Duke University Medical Center, Durham, NC, ²Columbia University Irving Medical Center, New York City, NY, ³Columbia University Irving Medical Center, New York, NY
*Purpose: In October 2018, a new heart transplantation allocation system was put into effect with the intent of better stratifying the most medically urgent candidates,…
2020 American Transplant Congress
Comparison of Six-Month Outcomes in Patients Bridged to Heart Transplantation with Percutaneous Temporary Circulatory Support Before and after the UNOS Allocation System Change
J. Nattiv¹, G. S. Liu¹, P. Banankhah¹, J. Sussex¹, P. Genyk¹, J. Li¹, D. Vucicevic², R. S. Chand³, K. Pandya¹, J. Rahman¹, A. M. Wolfson⁴, A. S. Vaidya¹, E. DePasquale¹
¹Keck Hospital of USC, Los Angeles, CA, ²Newark Beth Israel Medical Center, Newark, NJ, ³Harbor UCLA Medical Center, Los Angeles, CA, ⁴University of Arizona Sarver Heart Center, Tucson, AZ
*Purpose: We report the trends in utilization and outcomes of percutaneous temporary circulatory support (TCS) in the forms of Impella or TandemHeart as a bridge…
2019 American Transplant Congress
Incidence and Risk of Allograft Rejection after Cardiac Transplantation in Left Ventricular Assist Device Patients
R. C. Patel¹, L. B. Cooper², S. D. Barnett², R. T. Cole², M. A. Psotka², A. Cochrane², S. Sinha², L. J. Bogar², S. S. Desai², P. Shah²
¹Virginia Commonwealth University School of Medicine, Inova Fairfax Hospital, Falls Church, VA, ²Department of Heart Failure and Transplant, Inova Heart and Vascular Institute, Falls Church, VA
*Purpose: Left ventricular assist devices (LVAD) are made of biomaterials that have been shown to cause allosensitization. Single center studies have suggested that patients bridged…
2019 American Transplant Congress
Low Frequency Of Canonical Human Leukocyte Antigen Alloimmunization In Heart Transplantation Candidates With Ventricular Assist Devices
G. K. Mahowald¹, S. L. Saidman¹, G. Lewis², V. Pattanayak¹
¹Pathology, Massachusetts General Hospital, Boston, MA, ²Cardiology, Massachusetts General Hospital, Boston, MA
*Purpose: Screening for anti-HLA antibodies in heart transplantation candidates is complicated by transfusions as well as by the presence of ventricular assist devices (VADs), which…
2019 American Transplant Congress
Natural Antibodies and Left Ventricular Assist Device Complications
S. B. See¹, A. Pinsino², R. Shihab¹, N. Kunimune¹, D. Onat², E. Hittesdorf³, A. R. Garan², V. K. Topkara², Y. Naka⁴, H. Takayama⁴, K. Takeda⁴, P. Colombo², M. Yuzefpolskaya², G. Wagener³, E. Zorn¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Division of Cardiology, Columbia University, New York, NY, ³Department of Anesthesiology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Left ventricular assist devices (LVAD) are used as a bridge to heart transplantation or destination therapy for advanced heart failure. For all its benefits,…