2016 American Transplant Congress
Incidence of Post-Transplant Cardiovascular Disease After Pediatric Kidney Transplantation.
PURPOSE: Kidney transplant (KTx) recipients have increased risk of cardiovascular disease (CVD), related to time on dialysis and post-KTx immunosuppression. To date, the incidence of…2016 American Transplant Congress
Donor-Specific Antibody Is a Major Independent Predictor of Accelerated Heart Allograft Vasculopathy (CAV).
Introduction The role of circulating DSA in addition to traditional cardiovascular risk factors, in the development of accelerated CAV have not been demonstrated. We investigated…2016 American Transplant Congress
The 20S Proteasome, Active within Exosome-Like Vesicles Released by Apoptotic Cells Accelerates Rejection.
Apoptotic bodies (ApoBodies) and apoptotic exosome-like MV (ApoExo) released by apoptotic endothelial cells in vitro were purified by sequential centrifugation and analysed by electron microscopy…2016 American Transplant Congress
Prevalence of Polyreactive Innate-Like B Cells Among Graft-Infiltrating B Cells in Human Cardiac Allograft Vasculopathy.
Cardiac allograft vasculopathy (CAV) is a leading cause of death in long-term heart transplant survivors. Dense B cell infiltrates are common in heart transplants with…2015 American Transplant Congress
Paired-Donor Exchange Unrelated Living Donor Renal Transplantation With Two Separate Arterial Anastomoses to a Simultaneously Placed Vascular Prosthetic Interposition Graft in an Irradiated Field
BackgroundLack of suitable sites for arterial anastomoses presents a distinct challenge for renal transplantation in patients with significant peripheral arterial occlusive disease.MethodsWe present a case…2015 American Transplant Congress
Increased Vascular Stiffness in Pediatric Renal Transplant Recipients Despite Normal Kidney Function, Blood Pressure, and Body Mass Index
1Southern Illinois University, Springfield, IL; 2Washington University, St. Louis, MO.
Background: Chronic kidney disease (CKD) imparts enormous cardiovascular (CV) risk that is only partially improved by renal transplantation. We sought to understand the determinants of…2015 American Transplant Congress
High Incidence of Masked Hypertension in Pediatric Recipients of Stem Cell Transplantation
Purpose: Different from recipients of a solid organ transplant, stem cell transplantation (SCT) recipients do not receive long term immunosuppressive treatment that may cause renal…2015 American Transplant Congress
The Effects of Donor Specific Anti- Human Leukocyte Antigen Antibodies Late After Heart Transplantation
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: The development of anti-HLA antibodies following heart transplantation has been associated with poor outcomes, including lower survival and increased risk for the development of…2015 American Transplant Congress
Longitudinal Follow-Up of Cardiovascular Comorbidity in Pediatric Renal Transplant Recipients – Results from the 4C-T Study
Purpose: Children with chronic kidney disease (CKD) carry an increased cardiovascular risk. Cardiovascular death is the second leading cause of death in children after renal…2015 American Transplant Congress
Inhibition of RhoA Pathway-Related Macrophage Functions Abrogates Chronic Rejection of Cardiac Allograft
Objective. Chronic rejection remains the main obstacle in the long-term success of organ transplantation. The long-term survival of allografted hearts is limited by a progressive…
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