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Articles tagged "Vascular disease"

  • 2017 American Transplant Congress

    HLA, ANA, and ANCA Negative Vasculitis in Lung Transplantation Due to Overexpression of α1 Collagen V.

    E. Daoud,1 Y. Butt,1 F. Torres,2 T. Jose.1

    1Pathology, University of Texas Southwestern Medical Center, Dallas, TX; 2Lung Transplant Program, University of Texas Southwestern Medical Center, Dallas, TX

    The mechanism of fibrosing vasculopathy in lung allograft is poorly understood. A 58 year old man received a bilateral lung transplant for interstitial lung disease.…
  • 2017 American Transplant Congress

    Transcatheter Relief of Symptomatic Hepatic Venous Outflow Obstruction Following Pediatric Liver Transplantation.

    B. Goldstein, G. Tiao, M. Alonso, N. Johnson, J. Heubi, K. Averin, J. Bucuvalas.

    Cincinnati Children's Hospital, Cincinnati, OH

    Background: Technical-variant allograft (TVA) pediatric liver transplantation (LT) is associated with vascular complications. Early recognition and treatment of hepatic venous outflow obstruction (HVOO) may be…
  • 2017 American Transplant Congress

    Association Between Matrix-gla Protein Levels and Aortic Stiffness in Kidney Transplantation.

    M. Dinic,1 N. Maillard,1 P. Delanaye,2 J.-M. Krzesinski,2 A.-M. Saint-Remy,2 E. Cavalier,3 C. Mariat.1

    1Nephrology, Dialysis and Renal Transplantation, CHU Nord, Saint Etienne, France; 2Nephrology and Dialysis, University of Liège, CHU Sart Tilman, Liège, Belgium; 3Clinical Chemistry, University of Liège, CHU Sart Tilman, Liège, Belgium

    INTRODUCTIONAortic stiffness due to vascular calcifications is commonly observed among kidney transplant recipients and is considered as a predictive factor of poor events such as…
  • 2017 American Transplant Congress

    Renal Function, Albuminuria, and the Risk of Cardiovascular Events After Kidney Transplantation.

    N. Lam,1 M. Tonelli,2 K. Lentine,3 B. Hemmelgarn,2 F. Ye,1 A. Bello,1 S. Klarenbach.1

    1University of Alberta, Edmonton, Canada; 2University of Calgary, Calgary, Canada; 3Saint Louis University, St. Louis

    The risk of mortality and graft loss is higher in kidney transplant recipients with reduced estimated glomerular filtration rate (eGFR) and heavier albuminuria. It is…
  • 2016 American Transplant Congress

    Higher Functional Capacity Prior to Kidney Transplant Confers Lower Risk of New Onset Diabetes After Transplantation.

    I. Qaqish, S. Behmen, R. Heilman, H. Khamash, J. Huskey, S. Nair, H. Chakkera.

    Mayo Clinic, Phoenix, AZ.

    Background: New onset diabetes after transplantation (NODAT) adversely impacts both allograft function and patient survival. We hypothesize that higher functional capacity prior to kidney transplant…
  • 2016 American Transplant Congress

    Incidence of and Risk Assessment for Adverse Cardiovascular Outcomes Following Liver Transplantation: A Systematic Review.

    M. Konerman,1 D. Fritze,2 R. Weinberg,3 E. Spengler,1 C. Sonnenday,2 P. Sharma.1

    1Hepatology, Univ of Michigan, Ann Arbor, MI; 2Transplantation Surgery, Univ of Michigan, Ann Arbor, MI; 3Cardiology, Univ of Michigan, Ann Arbor, MI.

    Purpose: Cardiovascular (CV) events remain a major source of morbidity and mortality following liver transplantation (LT). This review evaluates the incidence of and risk assessment…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Cardiovascular Disease After Pediatric Kidney Transplantation.

    O. Serrano,1 A. Bangdiwala,2 D. Vock,2 W. Payne,1 T. Dunn,1 S. Chinnakotla,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas,1 B. Chavers.3

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics, Univ. of Minnesota, Minneapolis, MN; 3Pediatrics, Univ. of Minnesota, Minneapolis, MN.

    PURPOSE: Kidney transplant (KTx) recipients have increased risk of cardiovascular disease (CVD), related to time on dialysis and post-KTx immunosuppression. To date, the incidence of…
  • 2016 American Transplant Congress

    Donor-Specific Antibody Is a Major Independent Predictor of Accelerated Heart Allograft Vasculopathy (CAV).

    M. Bories,1 S. Varnous,2 C. Lefaucheur,3 P. Rouvier,2 R. Guillemain,1 P. Bruneval,1 J. Duong Van Huyen,4 A. Loupy.4

    1European Georges Pompidou Hospital, Paris, France; 2La Pitié Salpêtrière Hospital, Paris, France; 3Saint-Louis Hospital, Paris, France; 4Necker Hospital, Paris, France.

    Introduction The role of circulating DSA in addition to traditional cardiovascular risk factors, in the development of accelerated CAV have not been demonstrated. We investigated…
  • 2016 American Transplant Congress

    The 20S Proteasome, Active within Exosome-Like Vesicles Released by Apoptotic Cells Accelerates Rejection.

    M. Dieudé,1,4,5 C. Bell,2,5 J. Turgeon,1,5 D. Beillevaire,1,4,5 S. Qi,1,5 E. Boilard,3,5 P. Thibault,2,5 M.-J. Hébert.1,4,5

    1Research Centre Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada; 2Institute for research in immunology and cancer (IRIC), Montreal, Canada; 3Centre de Recherche du CHU de Québec, Québec, Canada; 4Université de Montréal, Montréal, Canada; 5Canadian National Transplant Research Program, Edmonton, Canada.

    Apoptotic bodies (ApoBodies) and apoptotic exosome-like MV (ApoExo) released by apoptotic endothelial cells in vitro were purified by sequential centrifugation and analysed by electron microscopy…
  • 2016 American Transplant Congress

    Prevalence of Polyreactive Innate-Like B Cells Among Graft-Infiltrating B Cells in Human Cardiac Allograft Vasculopathy.

    D. Chatterjee,1 C. Moore,2 B. Gao,3 K. Clerkin,1 S. See,1 D. Shaked,1 K. Rogers,1 S. Nunez,1 Y. Veras,1 L. Addonizio,1 M. Givertz,4 Y. Naka,1 D. Mancini,1 R. Vasilescu,5 C. Marboe,5 S. Restaino,1 J. Madsen,2 E. Zorn.1

    1Medicine, Columbia University Medical Center, NY, NY; 2Massachusetts General Hospital Transplant Center, Boston; 3First Hospital of Jilin University, Changchun, China; 4Brigham and Women's Hospital, Boston; 5Pathology & Cell Biology, Columbia University Medical Center, NY.

    Cardiac allograft vasculopathy (CAV) is a leading cause of death in long-term heart transplant survivors. Dense B cell infiltrates are common in heart transplants with…
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