Articles tagged "Vaccination"

2022 American Transplant Congress
Safety and Immunogenicity of Live Viral Vaccination After Pediatric Liver and Kidney Transplantation
A. Feldman¹, B. Beaty¹, N. Ebel², J. Ferrolino³, V. Gopalareddy⁴, J. Hollenbeck⁵, C. Jaramillo⁶, N. Kerkar⁷, S. Lerret⁸, G. Maron³, A. Mavis⁹, N. Ovchinsky¹⁰, M. Sell¹¹, T. Sharma¹², J. Stoll¹³, L. Danziger-Isakov¹⁴
¹UCD, Aurora, CO, ²Stanford, Palo Alto, CA, ³St. Jude, Memphis, TN, ⁴LCH, Charlotte, NC, ⁵Michigan Medicine, Ann Arbor, MI, ⁶PCH, Salt Lake City, UT, ⁷URMC, Rochester, NY, ⁸MCW, Milwaukee, WI, ⁹Duke, Durham, NC, ¹⁰Montefiore, NYC, NY, ¹¹MUSC, Charleston, SC, ¹²BCH, Boston, MA, ¹³WUSM, St Louis, MO, ¹⁴CCHMC, Cincinnati, OH
*Purpose: New recommendations suggest that measles-mumps-rubella vaccine (MMR-vx) and varicella vaccine (VZV-vx) may be administered to certain non-immune transplant recipients. The purpose of this study…
2022 American Transplant Congress
Safety and Immunogenicity of BNT-162b2 versus Chadox1 Vaccine in Solid Organ Transplant Recipients: Prospective Study
A. Ajlan¹, T. Ali², H. Aleid², K. Almeshari², M. Alkaff³, S. Althuwaidi⁴, L. Fajji², A. Alali⁵, D. Halabi⁶, A. Ullah⁷, K. H. Marquez⁸, B. Elmikkaoui⁹, A. Alrajhi¹⁰, A. Zidan¹¹, E. Albogumi.¹², K. Bzeizi¹³, R. Almaghrabi¹⁴, E. DeVol¹⁵, M. Al-Awwami,¹⁶, S. Alghamdi¹³, P. Broering²
¹Pharmaceutical Care Division - Organ Transplant Centre of Excellence, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riaydh, Saudi Arabia, ²Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ³Medical Laboratory, KFSHRC, Riaydh, Saudi Arabia, ⁴Medical Microbiology, KFSHRC, Riaydh, Saudi Arabia, ⁵Transplant Coordination Team - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ⁶Transplant Coordination Team - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ⁷Kidney & Pancreas Health Centre, KFSHRC, Riaydh, Saudi Arabia, ⁸Analytics Data Centre - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ⁹Data Management - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ¹⁰Infectious Diseases - Medicine Department, KFSHRC, Riaydh, Saudi Arabia, ¹¹Abdominal Transplant & Hepatobiliary Surgery Centre, KFSHRC, Riaydh, Saudi Arabia, ¹²Data Management. - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ¹³Liver & Small Bowel Health Centre, KFSHRC, Riaydh, Saudi Arabia, ¹⁴Infectious Diseases - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, ¹⁵Biostatistics, Epidemiology &Scientific Computing, KFSHRC, Riaydh, Saudi Arabia, ¹⁶Histocompatibility and Immunogenetics Laboratory Kidney & Pa - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia
*Purpose: Data showed seroconversion after different SARS-CoV-2 vaccination platforms might yield diminished response in transplant recipients. However, it is unknown whether different vaccination platforms could…
2022 American Transplant Congress
Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients
C. X. Qin¹, S. R. Auerbach², O. Charnaya¹, L. A. Danziger-Isakov³, N. H. Ebel⁴, A. G. Feldman², E. K. Hsu⁵, J. McAteer¹, S. Mohammad⁶, E. R. Perito⁷, A. M. Thomas¹, T. P. Chiang¹, J. M. Garonzik-Wang¹, D. L. Segev¹, D. B. Mogul¹
¹Johns Hopkins University, Baltimore, MD, ²University of Colorado, Aurora, CO, ³University of Cincinnati, Cincinnati, OH, ⁴Stanford University, Palo Alto, CA, ⁵University of Washington, Seattle, WA, ⁶Northwestern University, Chicago, IL, ⁷University of California San Francisco, San Francisco, CA
*Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…
2022 American Transplant Congress
Effect Of A Fourth Covid-19 Vaccine Dose On Omicron Variant Neutralization In Solid Organ Transplant Recipients
A. Karaba, A. Abedon, J. Alejo, C. X. Qin, D. Warren, J. Ruff, T. Aytenfisu, T. S. Johnston, O. Akinde, A. Pekosz, S. Klein, A. Cox, D. Segev, A. Tobian, W. Werbel
Johns Hopkins University, Baltimore, MD
*Purpose: Humoral response to COVID-19 vaccines is attenuated in many solid organ transplant recipients (SOTRs), necessitating additional primary and booster vaccinations. The omicron variant demonstrates…
2022 American Transplant Congress
Heterologous Vaccine Schedule Against Sars-CoV-2 with 2 Doses of Inactivated Virus and a Booster of mRNA BNT162b2 in Kidney Transplant Recipients
M. Seija¹, F. Rammauro², J. Santiago¹, N. Orihuela³, C. Zulberti³, D. Machado⁴, C. Recalde⁴, J. Noboa¹, R. Astesiano¹, F. Yandian¹, A. Guerisoli¹, A. Morra³, D. Cassinelli¹, A. Pippolo¹, B. De Aramburu¹, C. Coelho¹, P. González¹, R. Romero¹, R. Rodriguez-Teja⁴, G. Acuña⁴, V. Rabaza⁴, N. Perg⁴, R. Cordero⁴, S. Orihuela³, L. Curi³, E. Burgstaller⁴, O. Noboa¹, O. Pritsch², M. Nin¹, S. Bianchi⁵
¹Centro de Nefrología, Hospital de Clínicas. Facultad de Medicina UdeLaR, Montevideo, Uruguay, ²Departamento de Inmunobiología, Facultad de Medicina, UdeLaR, Montevideo, Uruguay, ³Hospital Italiano, Montevideo, Uruguay, ⁴Hospital Evangélico, Montevideo, Uruguay, ⁵Departamento de Fisiopatología, Facultad de Medicina UdeLar, Montevideo, Uruguay
*Purpose: Emerging evidence suggests that 3 doses of SARS-CoV-2 mRNA vaccine enhance immunity in kidney transplant (KT) patients. However, few studies have focused on humoral…
2022 American Transplant Congress
Lack of Measles Immunity and Vaccination Rates in Patients Being Evaluated for Solid Organ Transplant: Missed Opportunities
C. Larsen¹, C. Kotton²
¹Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, ²Massachusetts General Hospital, Boston, MA
*Purpose: Solid organ transplant (SOT) recipients are not eligible for live-vaccines, including the measles, mumps and rubella (MMR) vaccine, due to safety concerns on immunosuppression.…
2022 American Transplant Congress
Preliminary Data of the Safety and Immunogenicity Protocol of Vaccination for SARS-CoV 2 in Solid Organ Transplant Patients in Argentina
S. K. Villamil Cortez¹, J. R. Geffner², L. A. Barcan³, P. Remersano², A. Smud³, A. Villamil⁴, N. C. Imperiali¹, S. R. Groppa¹, C. A. Mombelli¹, V. A. Suarez Muñoz¹, C. Belziti⁵, F. Marcelo⁶, S. Di Pietrantonio⁷, G. J. Rosa Diez¹, M. C. Giordani¹
¹Nephrology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Inmunology, INBIRS CONICET, Buenos Aires, Argentina, ³Infectology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Hepatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Cardiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Nephrology, IOT Clinica de Nefrologia, Misiones, Argentina, ⁷Nephrology, Hospital El Cruce - Nestor Kirchner, Buenos Aires, Argentina
*Purpose: To evaluate the safety and generation rate of Ab anti spike rate in SOT patients at 28 and 90 days after completing the Covid…
2021 American Transplant Congress
Adjuvant Treatment Shapes the Bone Marrow Myeloid Compartment Towards an Immunosuppressive Phenotype That Can Suppress Allograft Rejection
J. Ge¹, E. Anderson¹, J. F. Markmann², A. Cuenca¹
¹Surgery, Boston Children's Hospital, Boston, MA, ²Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Myeloid derived suppressor cells (MDSCs) expand in response to inflammatory stimuli and have been shown to suppress adaptive immunity. Preliminary data from our lab…
2021 American Transplant Congress
Evaluation of Meningococcal Vaccine Response Among Solid Organ Transplant Recipients Receiving Eculizumab
R. Arora¹, C. Kane¹, K. Cunningham¹, M. Ison²
¹Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ²Divisions of Infectious Diseases and Organ Transplantation, Northwestern Memorial Hospital, Chicago, IL
*Purpose: Patients receiving eculizumab are at a 1,000-2,000-fold increased risk of invasive meningococcal infections. Therefore, the Advisory Committee for Immunization Practices recommends that these patients…
2021 American Transplant Congress
Pulmonary Infections in Patients with Kidney Transplant: Epidemiology, Risk Factors and Impact of a Dedicated Pre-Transplant Infectious Disease Consultation
E. Feredj
Infectious Disease, APHP Henri Mondor, Créteil, France
*Purpose: We aim to describe the spectrum of pulmonary infections after kidney transplant, to identify risk factors and to evaluate the impact of pre transplant…

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