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Articles tagged "Vaccination"

  • 2022 American Transplant Congress

    A Prospective Randomised, Controlled Trial Switching Sirolimus For Mycophenolate To Enhance Immunological Responses To Third Dose Covid-19 Vaccination In Kidney Transplant Recipients With Poor Baseline Humoral Immunity

    M. J. Tunbridge1, G. Perkins2, T. Salehi1, B. Grubor-Bauk3, B. Sim1, T. Ying4, J. J. Singer5, S. C. Barry6, P. Hissaria7, S. Chadban8, P. T. Coates1

    1Central and Northern Adelaide Renal and Transplant Services, Royal Adelaide Hospital, Adelaide, Australia, 2School of Biological Sciences, University of Adelaide, Adelaide, Australia, 3Basil Hetzel Institute, University of Adelaide, Adelaide, Australia, 4University of Sydney, Lilyfield, Ne, Australia, 5Kidney Node Laboratory, Charles Perkins Centre, The University of Sydney, The University of Sydney, Australia, 6School of Medical Sciences, University of Adelaide, Adelaide, Australia, 7Department of Immunology, Royal Adelaide Hospital, Adelaide, Australia, 8Department of Nephrology, Royal Prince Alfred Hospital, Sydney, Australia

    *Purpose: Kidney transplant recipients (KTR) have inadequate responses to 2-dose COVID vaccination schedules and are at increased risk of severe COVID-19. Formation of T cell…
  • 2022 American Transplant Congress

    SARS-CoV-2 Infection is Associated with Greater Neutralizing Antibody Response Compared to Three Doses of Mrna-1273 Vaccine in Solid Organ Transplant Recipients

    V. H. Ferreira, V. Hall, T. M. Marinelli, M. Ierullo, V. Kulasingam, A. Humar, D. Kumar

    University Health Network, Toronto, ON, Canada

    *Purpose: Prior studies suggest that two doses of mRNA vaccine in SOTR may result in lower antibody and T-cell responses relative to levels seen following…
  • 2022 American Transplant Congress

    Higher Immunogenicity of a Third Heterologous Dose with BNT262b2 Mensanger RNA Vaccine Compared to a Homologous Dose in Kidney Transplant Recipients Fully Vaccinated with Inactivated Whole-Virion CoronaVac Vaccine

    L. V. Pouzo1, M. Nakamura1, L. A. Viana2, E. Lucena1, M. Jesus1, G. Bittencourt Pereira Lima1, J. Medina1, H. Tedesco1, M. Cristelli1

    1Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil, 2Nephrology, Hospital do rim, Sao Paulo, Brazil

    *Purpose: This study aims to compare the immunogenicity of a third dose of the heterologous BNT262b2 mRNA vaccine versus the homologous inactivated whole-virion CoronaVac vaccine…
  • 2022 American Transplant Congress

    Pathological Changes in Kidney Allografts Associated with COVID-19 Vaccination

    S. Shelton, N. Hellenga, P. Burke

    Christiana Care Health System - Kidney Transplant Program, Newark, DE

    *Purpose: The Coronavirus Disease 2019 (COVID-19) pandemic prompted widespread vaccination for the immunosuppressed population starting in January 2021 with minimal information on safety outcomes. The…
  • 2022 American Transplant Congress

    Survey of Current Transplant Center Practices Regarding Covid-19 Vaccine Mandates in the United States

    B. E. Hippen1, D. Axelrod2, K. Maher3, R. Xi3, D. Kumar4, M. Schnitzler3, K. Lentine3

    1Head of Transplant Medicine, Fresenius Medical Care, Charlotte, NC, 2University of Iowa Transplant Clinic, Iowa City, IA, 3St. Louis University School of Medicine, St. Louis, MO, 4Ajmera Transplant Centre, Toronto, ON, Canada

    *Purpose: We surveyed current policies of transplant centers regarding a COVID-19 vaccine mandate, and rationales for or against a mandate policy.*Methods: An electronic survey was…
  • 2022 American Transplant Congress

    Seroprevalence of MMR and Varicella (MMRV) in Solid Organ Transplant Candidates and Seroresponse to MMRV Vaccinations

    H. Javaid1, R. Hasbun1, A. DeGolovine2, S. Jyothula3, V. Machicao4, J. Bynon5, L. Ostrosky1, M. Nigo1

    1Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 2Div of Renal Disease, Univ of Texas Health Science Center, Houston, TX, 3Div of Advanced Heart Failure and Transplant Cardiology, Univ of Texas Health Science Center, Houston, TX, 4Div of Transplant Hepatology, Univ of Texas Health Science Center, Houston, TX, 5Div of Immunology and Organ Transplantation, Univ of Texas Health Science Center, Houston, TX

    *Purpose: Updating live vaccines such as MMR and varicella (MMRV) is an important step in preparing patients during the pre-solid organ transplant (SOT) period. While…
  • 2022 American Transplant Congress

    Impact of Sars-CoV-2 Vaccination on Donor-Derived Cell Free DNA Levels in Renal Transplant Recipients

    H. Alvarado Verduzco, E. Daniel, D. Kim, A. Hussain, S. Mohan, D. Cohen

    Columbia University Irving Medical Center, New York, NY

    *Purpose: COVID-19 poses a disproportionate threat to renal transplant recipients (RTR), who are chronically immunosuppressed. Studies have indicated a 16% mortality rate compared to
  • 2021 American Transplant Congress

    Impact of a Pharmacist-driven Immunization Clinic on Vaccination Rates in Pre-liver Transplant Patients

    A. Poparad-Stezar1, B. Summers1, M. Fitzmaurice1, K. Hakamiun2, N. Sulejmani3, A. Jantz1

    1Henry Ford Hospital, Detroit, MI, 2Select Medical, Wyandotte, MI, 3CareDx, Inc., Sterling Heights, MI

    *Purpose: Infectious diseases are a leading cause of morbidity and mortality among patients with end-stage liver disease (ESLD). Vaccination data of ESLD patients pre- and…
  • 2021 American Transplant Congress

    Safety of Sars-cov-2 Mrna Vaccines in Solid Organ Transplant Recipients

    M. Ou, B. Boyarsky, J. Motter, R. Greenberg, A. Teles, J. Ruddy, M. Krach, W. Werbel, R. Avery, A. Massie, D. Segev, J. Garonzik-Wang

    Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: The safety of SARS-CoV-2 mRNA vaccines in solid organ transplant recipients (SOTRs) remains unknown. We investigated adverse events in SOTRs who received these mRNA…
  • 2021 American Transplant Congress

    Limited Immunogenicity of a Single Dose of Sars-cov-2 Mrna Vaccine in Solid Organ Transplant Recipients

    B. Boyarsky, M. Ou, R. Greenberg, A. Teles, W. Werbel, R. Avery, A. Tobian, A. Massie, D. Segev, J. Garonzik Wang

    Johns Hopkins, Baltimore, MD

    *Purpose: Given substantial challenges with vaccine allocation and evidence for short-term vaccine efficacy after a single dose of SARS-CoV-2 mRNA vaccines in clinical trials, some…
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