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Articles tagged "Vaccination"

  • 2022 American Transplant Congress

    Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients

    A. Al Jurdi1, R. B. Gassen1, T. Borges1, I. T. Lape1, L. Morena1, O. Efe1, Z. Solhjou2, R. El Fekih2, C. Kotton1, J. Azzi2, L. Riella1

    1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    *Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
  • 2022 American Transplant Congress

    Serological Response To Three, Four And Five Doses Of Sars-cov-2 Vaccine In Kidney Transplant Recipients

    S. Ronicke1, B. Osmanodja1, K. Budde1, A. Jens1, C. Hammett1, K. Nadine1, J. Waiser1, B. Zukunft1, F. Bachmann1, M. Choi1, W. Ulrike1, B. Eberspächer2, J. Hofmann2, F. Grunow1, M. Mikhailov1, L. Liefeldt1, K. Eckardt1, F. Halleck1, E. Schrezenmeier1

    1Department of Nephrology and Medical Intensive Care, Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Labor Berlin - Charité Vivantes GmbH, Berlin, Germany

    *Purpose: Mortality from COVID-19 among kidney transplant recipients (KTR) is unacceptably high, and their response to up to three vaccinations against SARS-CoV-2 is strongly impaired.…
  • 2022 American Transplant Congress

    Three Month Antibody Durability and Kinetics in Sars-cov-2 Mrna Vaccinated Heart and Lung Transplant Recipients: Differences Above the Diaphragm

    J. L. Alejo1, J. Ruck1, T. Chiang1, A. Abedon1, J. Kim1, R. Avery1, A. Tobian1, M. Levan1, D. Warren1, A. Massie1, W. Werbel1, J. Garonzik-Wang2, D. Segev1

    1Johns Hopkins, Baltimore, MD, 2University of Wisconsin, Madison, WI

    *Purpose: Heart and lung transplant (HT/LT) recipients have impaired humoral responses to SARS-CoV-2 vaccination compared to other solid organ transplant recipients (SOTRs). The purpose of…
  • 2022 American Transplant Congress

    CoVID-19 Vaccine Efficacy in Heart Transplant Recipients, a Single Center Experience

    M. Yu1, S. B. Sharmin2, C. Joyce3, Z. Pieters1, S. DeSirkar1, M. Thomas1, S. Kim1, E. Bruno1, M. Liebo1, A. Heroux4, N. Clark1, G. Reid1, S. Uprichard2

    1Loyola University Medical Center, Maywood, IL, 2Microbiology and Immunology, Loyola University Chicago, Chicago, IL, 3Department of Public Health Sciences, Loyola University Chicago, Chicago, IL, 4Loyola Univ Medical Ctr, Maywood, IL

    *Purpose: Transplant recipients have worse CoVID-19 survival compared to the general population, and thus are recommended to be vaccinated and boosted. Determinants of vaccination efficacy…
  • 2022 American Transplant Congress

    Acute Cellular Rejection in Liver Transplant Recipients Following Vaccination Against Covid-19

    R. Sarwar1, O. Adeyi2, N. Lim1

    1Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, 2Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: The coronavirus disease 2019 (COVID-19) global pandemic has seen the development of effective vaccines in record time. We report a series of five liver…
  • 2022 American Transplant Congress

    Attitudes Regarding COVID-19 Vaccine and Vaccine Hesitancy in an Inner-City Kidney Transplant Recipients (KTRs)

    E. Bae, L. Wei, C. Canning, S. Martinez-Machado, J. Lee, L. Patel, M. Markell

    SUNY Downstate Health Sciences University, Brooklyn, NY

    *Purpose: KTRs comprise a high-risk group for COVID-19 infection due to comorbidities and immunosuppression. Studying how vaccination hesitancy in inner-city KTRs has changed since the…
  • 2022 American Transplant Congress

    Comparing The Immunologic Responses Between Kidney Transplant Recipients Receiving Standard Immunosuppression And CNI Reduction After Two Doses Of ChAdOx-1 And A Booster Dose BNT162b2

    S. Phirom1, T. Kitrungphaiboon2, W. Jantarabenjakul2, Y. Avihingsanon2, W. Prasithsirikul3, J. Vanichanan4, P. Hansasuta5, N. Townamchai6

    1Nephrology division, Department of medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 2King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 3Bamrasnaradura infectious disease institute, Bangkok, Thailand, 4Infectious diseases, Department of medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 5Department of Microbiology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 6Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand

    *Purpose: Immunosuppression can impair immunological responses after vaccination in kidney transplant recipients (KTR). However, little is known about the effect of the booster dose of…
  • 2022 American Transplant Congress

    Sars-cov-2 Antibodies Transitions After Vaccination In Solid Organ Transplant Recipients: Multicenter Study In Japan

    K. Unagami1, M. Yoshikawa2, Y. Natori3, K. Omoto1, H. Ishida1, H. Date4, R. Imamura5, T. Ito4, K. Miyaji6, S. Takahara7, K. Yuzawa8, O. Satoko9, Y. Hirota10, H. Egawa1

    1Tokyo Women's Medical University, Tokyo, Japan, 2Kyoto Prefectural University of Medicine, Kyoto, Japan, 3University of Miami, Pinecrest, FL, 4Kyoto University, Kyoto, Japan, 5Dept. of Urology, Osaka Univ. Graduate School of Medicine, Suita, Japan, 6Renal Transplantation, Takatsuki General Hospital, Takatsuki, Japan, 7Kansai Medical Hospital, Toyonaka, Japan, 8Tranplantation Surgery, National Hospital Organization Mito Medical Center, Mito, Japan, 9Public Health, Osaka City University Graduate School of Medicine and Research Center for Infectious, Osaka City University Graduate School of Medicine, Osaka, Japan, 10Clinical Epidemiology Research Center, Miyama, Japan

    *Purpose: For purpose of SARS-CoV-2 infection control, vaccination was started in worldwide, however, low reactivity of antibody production after vaccination is a concern for solid…
  • 2022 American Transplant Congress

    Effect of Mycophenolate Mofetil Dosing on Antibody Response to SARS-CoV-2 Vaccination in Heart and Lung Transplant Recipients

    J. Mitchell1, T. P. Chiang1, J. Alejo1, A. Chang1, A. Abedon1, R. Avery1, A. Tobian1, A. Massie1, M. Levan1, D. Warren1, J. Garonzik-Wang2, D. Segev1, W. Werbel1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin-Madison, Madison, WI

    *Purpose: Mycophenolate mofetil (MMF) use is associated with decreased antibody response to the SARS-CoV-2 mRNA vaccine series in heart and lung transplant recipients (HLTRs). Higher…
  • 2022 American Transplant Congress

    A Machine Learning Model for Predicting Antibody Response to 2-Dose Sars-cov-2 MRNA Vaccine Series in Transplant Recipients

    J. L. Alejo1, J. Mitchell1, T. Chiang1, A. Abedon1, W. Werbel1, R. Avery1, A. Tobian1, A. Massie1, J. Garonzik-Wang2, D. Segev1, S. Bae1

    1JHU, Baltimore, MD, 2U of Wisconsin, Madison, WI

    *Purpose: Understanding risk factors for impaired vaccine responses can guide strategies for testing, additional dose recommendations, and vaccine schedules to provide improved protection in solid…
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