2022 American Transplant Congress
High Case Fatality Rate Among Fully Vaccinated Kidney Transplant Recipients with Breakthrough Covid-19 During the Delta Surge
Rhode Island Hospital/Brown University, Providence, RI
*Purpose: Organ transplant recipients (OTR) have worse outcomes from COVID-19 and weaker antibody responses to vaccination than do immunocompetent individuals. Data on clinical outcomes among…2022 American Transplant Congress
Evolution of Cellular and Humoral Immunity During and After a Three Doses-Course of mRNA-1273 COVID-19 Vaccine in Kidney Transplant Recipients
*Purpose: Seroconversion after a 2 doses of mRNA COVID-19 vaccine in kidney transplant recipients (KTR) ranges between 30 and 50% in different series. We previously…2022 American Transplant Congress
Transplant Patients Risk for SARS-CoV-2 Infection Post-2nd Vaccine Dose; We Are Not Home and Dry Yet
*Purpose: SARS-CoV-2 is associated with high mortality among transplant recipients. Data of transplant patients’ infections post-2nd vaccine dose is not available. The aim of the…2022 American Transplant Congress
COVID-19 Vaccination Induces a Poor Interleukin-21 Memory T-cell Response in Kidney Transplant Recipients
*Purpose: COVID-19-related morbidity and mortality is high among kidney patients. Several studies recently suggested low humoral and cellular immune responses after two doses of mRNA-1273…2022 American Transplant Congress
Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients
Brigham & Women's Hospital, Boston, MA
*Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…2022 American Transplant Congress
Clinical Characteristics Of Serologic Non-responders To Covid-19 Booster Vaccination In A Cohort Of Solid Organ Transplant Recipients.
*Purpose: The purpose of this study was to assess the clinical characteristics of serologic non-responders to COVID-19 booster vaccination in a cohort of solid organ…2022 American Transplant Congress
Impaired Cellular Immunity and Elevated Myeloid Derived Suppressor Cells in Kidney Transplant Recipients with Impaired Antibody Response to Covid-19 Vaccination
1AdventHealth Transplant Institute, Orlando, FL, 2Plexision, Inc, Pittsburgh, PA
*Purpose: To evaluate post-vaccination cellular and antibody (Ab) immunity after COVID-19 vaccination in single blood samples from 17 kidney transplant (KT) recipients who had received…2022 American Transplant Congress
T and B Cell Response to 3 Dose Covid Vaccine Series for Kidney Transplant Patients on Belatacept
*Purpose: Data shows COVID vaccine response after 2 doses in patients on Belatacept immunosuppression (IS) is low, with reported rates of seroconversion (as measured by…2022 American Transplant Congress
Real-Life Prevention of Breakthrough SARS-CoV-2 Infections by mRNA Vaccines in Kidney Transplant Recipients vs Hemodialysis Patients
Nephrology and Renal Transplantation, Hospital Clinic of Barcelona, Barcelona, Spain
*Purpose: The increased COVID-19 severity observed in kidney transplant recipients (KTR) has been widely reported. In addition, several studies have shown a reduced humoral and…2022 American Transplant Congress
Higher Proinflammatory Cytokines Are Associated with Increased Antibody Titer After a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients
*Purpose: Solid organ transplant recipients (SOTRs) are at increased risk for severe COVID-19 and exhibit lower antibody responses to SARS-CoV-2 vaccines. This study aimed to…
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