2016 American Transplant Congress
A 5-Year Multicenter Evaluation of Seasonal Influenza Infection in Transplant Recipients.
Background:Seasonal influenza infection may cause significant morbidity and mortality in transplant patients. However, there are limited prospective data on clinical presentations and determinants of outcomes.…2015 American Transplant Congress
Boosting the Adaptive Immune Response Prevents the High Incidence of Herpes Zoster After Lung or Heart Transplantation
Purpose Primary varicella zoster virus (VZV) infection causes varicella and lifelong latent infection in ganglia from which it may reactivate leading to herpes zoster (HZ).…2015 American Transplant Congress
Vaccination to Prevent the High Herpes Zoster Incidence After Renal Transplantation
Introduction: Herpes zoster (HZ) is the clinical manifestation of varicella zoster virus (VZV) reactivation and occurs more frequently in people with a suppressed immune system.…2015 American Transplant Congress
The Effect of Influenza Vaccination on Hospital Admission in Solid Organ Transplant Recipients
Emory University Hospital, Atlanta, GA.
Purpose: The current study has two objectives. First, compare clinical outcomes between solid organ transplant (SOT) recipients who receive influenza vaccination and those who do…2015 American Transplant Congress
CFZ533: Assessment of Immunomodulatory Activity Following Single Doses of a Novel Anti-CD40 mAb in Healthy Volunteers
Blocking the CD40-CD154 pathway has been shown to effectively prolong renal allograft survival in non-human primates. CFZ533 is a novel, fully human, Fc-silent, anti-CD40 monoclonal…2015 American Transplant Congress
Vaccine-Induced 'Incognito' CD8+ T Cell Memory Can Disrupt Transplantation Tolerance
Transplant recipients harbor immunity to vaccines and pathogens (e.g. CMV, EBV). Pre-existing immunity can have significant antigen-specific ramifications, usually attributed to heterologous immunity, as pathogen-reactive…2015 American Transplant Congress
Antibody Response Following Influenza Vaccination in Renal Transplant Recipients
Indiana University School of Medicne-IU Health, Indianapolis, IN.
Purpose: Following the recommended consensus guidelines of ATC for vaccination, at our institution we recommend annual vaccination for influenza + H1N1 (Flu) for renal transplant…2015 American Transplant Congress
Primary and Secondary Vaccine Responses in a Non-Human Primate Model of Cardiac Allotransplantation
Purpose: To compare the effect of calcineurin- versus costimulation-based immunosuppression on primary and secondary vaccine responses in non-human primate heart transplant recipients.Background: Antibody response following…2015 American Transplant Congress
Early Antibody Mediated Rejection in HLA Antibody Incompatible Kidney Transplantation A Treatable Condition Without Heavy Induction Immunosuppression
Transplantation across preformed donor specific HLA antibodies (DSA) not only carries a risk of early acute antibody mediated rejection (AMR) and graft loss, but also…2015 American Transplant Congress
Outbreak of Pandemic Influenza A (H1N1pdm) in a Kidney Transplant Unit The Protective Effect of Vaccination
Background: Seasonal influenza vaccination is recommended for patients with end-stage renal disease, although the efficacy of the vaccination among these patients is unknown. We characterize…