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Articles tagged "Vaccination"

  • 2016 American Transplant Congress

    Post-Transplant Vaccine Initiative Collaboration (VIC) in a Multidisciplinary, Transplant Ambulatory Setting.

    G. Malat,4 S. DiLollo,1 D. Lee,2 A. Sharma,3 T. Bias,2 M. Harhay,3 K. Ranganna,3 A. Doyle.3

    1Colonia Natural Pharmacy, Colonia; 2Medicine/Surgery, Drexel University, Philadelphia.

    Introduction We describe the implementation of a vaccine initiative in an ambulatory transplant setting.Methods In 2014, Hahnemann University Hospital (HUH) and Colonia Natural Pharmacy transplant…
  • 2015 American Transplant Congress

    Vaccination to Prevent the High Herpes Zoster Incidence After Renal Transplantation

    M. Kho,1 W. Weimar,1 D. Boveé,1 M. Boer-Verschragen,1 A. van der Eijk,2 N. van Besouw.1

    1Internal Medicine - Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, Netherlands; 2Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.

    Introduction: Herpes zoster (HZ) is the clinical manifestation of varicella zoster virus (VZV) reactivation and occurs more frequently in people with a suppressed immune system.…
  • 2015 American Transplant Congress

    The Effect of Influenza Vaccination on Hospital Admission in Solid Organ Transplant Recipients

    J. Rago, M. Hurtik, S. Todd, A. Mehta, G. Lyon III.

    Emory University Hospital, Atlanta, GA.

    Purpose: The current study has two objectives. First, compare clinical outcomes between solid organ transplant (SOT) recipients who receive influenza vaccination and those who do…
  • 2015 American Transplant Congress

    CFZ533: Assessment of Immunomodulatory Activity Following Single Doses of a Novel Anti-CD40 mAb in Healthy Volunteers

    A. Slade,1 J. Doucet,2 P. Koo,1 P. Espie,2 J. Rush,2 C. Tomek,3 J. Klupp.2

    1Novartis Institute for Biomedical Research, East Hanover, NJ; 2Novartis Institute for Biomedical Research, Basel, Switzerland; 3Celerion, Inc, Lincoln, NE.

    Blocking the CD40-CD154 pathway has been shown to effectively prolong renal allograft survival in non-human primates. CFZ533 is a novel, fully human, Fc-silent, anti-CD40 monoclonal…
  • 2015 American Transplant Congress

    Vaccine-Induced 'Incognito' CD8+ T Cell Memory Can Disrupt Transplantation Tolerance

    M. Nelsen,1 K. Beard,2 R. Kedl,1 R. Gill.2

    1Dept of Immunology & Microbiology, Univ of Colorado, Aurora, CO; 2Dept of Surgery, Univ of Colorado, Aurora, CO.

    Transplant recipients harbor immunity to vaccines and pathogens (e.g. CMV, EBV). Pre-existing immunity can have significant antigen-specific ramifications, usually attributed to heterologous immunity, as pathogen-reactive…
  • 2015 American Transplant Congress

    Antibody Response Following Influenza Vaccination in Renal Transplant Recipients

    M. Mujtaba, B. Book, A. Sharfuddin, A. Khalil, S. Vaishnav, E. Wiebke, M. Yaqub, D. Mishler, T. Taber.

    Indiana University School of Medicne-IU Health, Indianapolis, IN.

    Purpose: Following the recommended consensus guidelines of ATC for vaccination, at our institution we recommend annual vaccination for influenza + H1N1 (Flu) for renal transplant…
  • 2015 American Transplant Congress

    Primary and Secondary Vaccine Responses in a Non-Human Primate Model of Cardiac Allotransplantation

    S. Dahi,1 E. Kang,1 T. Zhang,1 B. Vanhove,2 A. Azimzadeh,1 R. Pierson III.1

    1Department of Surgery, University of Maryland School of Medicine, Baltimore, MD; 2INSERM, Nantes, France.

    Purpose: To compare the effect of calcineurin- versus costimulation-based immunosuppression on primary and secondary vaccine responses in non-human primate heart transplant recipients.Background: Antibody response following…
  • 2015 American Transplant Congress

    Early Antibody Mediated Rejection in HLA Antibody Incompatible Kidney Transplantation – A Treatable Condition Without Heavy Induction Immunosuppression

    S. Daga,1,2 N. Krishnan,1 D. Lowe,3 F. Lam,1 C. Imray,1,2 H. Kashi,1 L. Tan,1 D. Briggs,3 R. Higgins.1,2

    1Renal Department, University Hospital, Coventry, United Kingdom; 2Warwick Medical School, University of Warwick, Coventry, United Kingdom; 3H&I Department, NHSBT, Birmingham, United Kingdom.

    Transplantation across preformed donor specific HLA antibodies (DSA) not only carries a risk of early acute antibody mediated rejection (AMR) and graft loss, but also…
  • 2015 American Transplant Congress

    Outbreak of Pandemic Influenza A (H1N1pdm) in a Kidney Transplant Unit – The Protective Effect of Vaccination

    I. Helanterä,1 V.-J. Anttila,2 M. Lappalainen,3 M. Lempinen,1 H. Isoniemi.1

    1Department of Transplant and Liver Surgery, Helsinki University Central Hospital, Helsinki, Finland; 2Department of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland; 3Department of Virology, Helsinki University Central Hospital, Helsinki, Finland.

    Background: Seasonal influenza vaccination is recommended for patients with end-stage renal disease, although the efficacy of the vaccination among these patients is unknown. We characterize…
  • 2015 American Transplant Congress

    Heterologous Immune Responses to Influenza Vaccine in Kidney Transplant Recipients

    D. Kumar,1 P. Campbell,2 K. Hoschler,3 A. Humar.1

    1Univ Health Network, Toronto, Canada; 2Univ of Alberta, Edmonton, Canada; 3Public Health England, London, United Kingdom.

    Background:Influenza vaccine is known to have suboptimal immunogenicity in transplant recipients. However, influenza vaccine may have the added benefit of inducing a cross-reactive immune response…
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