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Articles tagged "Vaccination"

  • 2017 American Transplant Congress

    Effect of Statins on Influenza Vaccine Antibody Concentrations in Lung Transplant Recipients.

    A. Condon,1 C. Garmoe,2 M. Hayney.2

    1Department of Pharmacy, UW Health, Madison, WI; 2School of Pharmacy, University of Wisconsin, Madison, WI

    Background: Large population studies have shown that statin use at the time of influenza immunization is associated with lower antibody concentrations and decreased vaccine efficacy.…
  • 2017 American Transplant Congress

    Improving Vaccination Rates for Lung Transplant Candidates.

    M. Cortez,1 R. Bag,2 L. Potter.1

    1Pharmacy, The University of Chicago Medicine, Chicago, IL; 2Transplant Center, The University of Chicago Medicine, Chicago, IL

    In 2015, transplant pharmacists at the University of Chicago identified an opportunity to improve vaccination rates for transplant candidates. On 10/1/15, a pharmacist-led program was…
  • 2017 American Transplant Congress

    MMR and Varicella Immunity After Pediatric Liver Transplant.

    A. Waugh,1 A. Opekun,1,2 F. Munoz,2 T. Miloh.2

    1Baylor College of Medicine, Houston; 2Texas Children's Hospital, Houston

    Background: Children listed for liver transplantation (LT) are at risk for decreased vaccine response due to age, underlying disease, or waning immunity. Live attenuated vaccines…
  • 2017 American Transplant Congress

    Successful Implementation of a Pneumococcal Vaccination Program for Pediatric Kidney Transplant Recipients.

    K. Sprott, S. Nadig, K. Twombley.

    Medical University of South Carolina, Charleston

    Vaccine preventable diseases remain a serious problem among transplanted patients. Many children remain under vaccinated after a kidney transplant because of a lack of physician…
  • 2017 American Transplant Congress

    Impact of a Pharmacist-Led Vaccine Recommendation Program for Pediatric Kidney Transplant Candidates.

    C. Carthon,1 R. Hall,2 P. Maxwell,2 B. Crowther.2

    1Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; 2University Transplant Center, University Health System, San Antonio, TX

    Pediatric transplant recipients commonly have a deficient immunization status at the time of transplantation. Utilizing transplant pharmacists to improve these immunization rates has not previously…
  • 2017 American Transplant Congress

    Spousal Transmission of Hepatitis B from a Hepatitis B Core Antibody Positive Liver Transplant Recipient – A Case Report.

    J. Gripshover, K. Hidalgo, B. Ravichandran.

    University of Maryland Medical Center, Baltimore, MD

    IntroductionGiven the shortage of donor organs, hepatitis B core antibody positive (HBcAb+) donors have been utilized to increase access to transplantation. It is well established…
  • 2017 American Transplant Congress

    Efficacy and Safety of ASP0113 versus Placebo in CMV-Seronegative Kidney Transplant Patients Receiving an Organ from a CMV-Seropositive Donor.

    F. Vincenti,1 K. Budde,2 P. Merville,3 F. Shihab,4 V. Peddi,5 M. Shah,6 E. Cassuto-Viguier,7 A. Weidemann,8,9 M. Lee,10 T. Flegel,10 J. Erdman,10 X. Wang,10 C. Lademacher.10

    1UCSF, San Francisco; 2Charité Universitätsmedizin, Berlin, Germany; 3Université de Bordeaux, Bordeaux, France; 4University of Utah, Salt Lake City; 5California Pacific Medical Center, San Francisco; 6University of Kentucky, Lexington; 7Centre Hospitalier Universitaire de Nice, Nice, France; 8Universitätsklinikum Erlangen, Erlangen, Germany; 9Kliniken Köln, Cologne, Germany; 10Astellas Pharma Global Development, Chicago

    Introduction: ASP0113 is a first-in-class DNA-based vaccine in development for the prevention of human cytomegalovirus (CMV) infection in at-risk hematopoietic cell transplant and solid organ…
  • 2017 American Transplant Congress

    Influenza Viral Dynamics in a Large Cohort of Transplant Patients with Natural Influenza Infection.

    V. Ferreira,1 A. Humar,1 E. Cordero,2 E. Blumberg,3 A. Limaye,8 F. Silveira,5 L. Danziger-Isakov,6 M. Levi,7 J. Kalpoe,4 J. Englund,9 M. Multicenter Influenza Group, D. Kumar.1

    1UHN, Toronto, Canada; 2REIPI, Seville, Spain; 3UPenn, Philadelphia; 4LUMC, Leiden, Netherlands; 5UPMC, Pittsburgh; 6CCHMC, Cincinnati; 7UCD, Denver; 8UW, Seattle; 9SCH, Seattle

    Background:Influenza infection significantly impacts transplant patients. Despite this, there are limited data on how virological characteristics, including influenza viral load (VL), impact the outcome of…
  • 2017 American Transplant Congress

    T Cell Responses to Viral Peptide Stimulation Predict Influenza Vaccine-Induced Seroconversion in Pediatric Solid Organ Transplant Recipients.

    E. Mayer,1 M. Altrich,2 C. Cordes,2 S. Fausett,2 J. Tepp,3 R. Albrecht,3 A. Fernandez-Sesma,3 B. Herold,1 I. Ramos,3 R. Madan.1

    1Pediatrics, Albert Einstein College of Medicine, Bronx, NY; 2Viracor Eurofins, Lee's Summit, MO; 3Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY

    Introduction: Biomarkers predictive of vaccine response are needed to determine the optimal timing of immunization post-transplantation. We previously found that low T-cell ELISPOT responses to…
  • 2017 American Transplant Congress

    ASP0113 Elicits an Immune Response in CMV-Seronegative Dialysis Patients: Comparison to Healthy Subjects.

    P. Bonate,1 C. Van Sant,2 K. Cho,1 E. Zook,1 L. Smith,3 S. Boutsaboualoy, X. Wang,1 R. Wu,1 A. Koester,4 D. Rammelsberg,6 R. Goldwater,4 T. Marbury.5

    1Astellas Pharma Global Development, Northbrook; 2Astellas Research Institute of America, Skokie; 3Vical Inc, San Diego; 4PAREXEL International, Baltimore; 5Orlando Clinical Research Center, Orlando; 6Randstad Pharma, Deerfield, IL, United States (on assignment at Astellas Pharma Global Development, Northbrook, United States)

    Introduction: ASP0113 is a first-in-class, DNA-based vaccine in development for the prevention of CMV infection in at-risk hematopoietic cell transplant.Methods: A Phase 1, single-blind, parallel-group,…
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