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Articles tagged "Vaccination"

  • 2019 American Transplant Congress

    A CMV Vaccine Based on Non-Replicating Lymphocytic Choriomeningitis Virus Vectors Expressing gB and pp65 is Safe and Immunogenic in Healthy Volunteers and Entering a Phase 2 Trial in Kidney Transplant Recipients

    C. N. Kotton1, M. Schwendinger2, G. Thiry3, B. De Vos4, F. De Boever5, G. Leroux-Roels6, A. Lilja7

    1Infectious Diseases Division, Boston, MA, 2Hookipa Biotech AG, Vienna, Austria, 3Hookipa Biotech GmbH, VIenna, Austria, 4Bejamad sprl/bvba, Beersel, Belgium, 5Centrum voor vaccinologie (CEVAC), Gdent, Belgium, 6Centrum voor vaccinologie (CEVAC), Gent, Belgium, 7Hookipa Biotech GmbH, Vienna, Austria

    *Purpose: Cytomegalovirus (CMV) is a significant pathogen in pregnancy and immunocompromised patients. Antiviral prophylaxis is limited by toxicities, recurrent infection, and resistance. A safe and…
  • 2019 American Transplant Congress

    Vaccine Response as a Predictor of Kidney Transplant Rejection and Serious Infection

    A. Ta'eed, K. R. Polkinghorne, W. R. Mulley

    Department of Nephrology, Monash Health, Clayton, Australia

    *Purpose: Vaccination generates immune memory, including antibodies against harmful pathogens. Transplant immunosuppression prevents similar processes occurring against alloantigens. Transplant recipients have significantly reduced seroresponses to…
  • 2019 American Transplant Congress

    A Nurse-Driven Influenza Vaccine Ordering Protocol Improves Vaccination Rates in Abdominal Organ Transplant Recipients

    T. Ho1, C. D. Sifri2, J. D. Lewis3

    1Department of Medicine, Virginia Commonwealth University, Richmond, VA, 2Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, 3Division of Infectious Diseases, Medical University of South Carolina, Charleston, SC

    *Purpose: Solid organ transplant (SOT) recipients are at increased risk of influenza infection and severe influenza-related complications. The influenza vaccine is a safe and effective…
  • 2018 American Transplant Congress

    The Impact of the Influenza Vaccine on Pediatric Kidney Transplant Outcomes

    M. Camerino,1 S. Jackson,2 S. Chinnakotla,3 P. Verghese.1

    1Department of Pediatrics, University of Minnesota, Minneapolis, MN; 2Fairview Health Services, Minneapolis, MN; 3Department of Surgery, University of Minnesota, Minneapolis, MN.

    The influenza vaccine has been associated with de novo DSA and rejection in adult kidney recipients. This risk has not been adequately assessed in pediatric…
  • 2018 American Transplant Congress

    Measles and Varicella Vaccination Status and Evidence of Immunity during Solid Organ Pre-Transplantation Evaluation

    H. Daniels, C. Saracusa, S. Worley, B. Gonzalez.

    Pediatric Infectious Diseases, Cleveland Clinic, Cleveland, OH.

    Background: Ensuring complete vaccination is important during a pre-transplant evaluation (PTE), especially for live viral vaccines which are generally contraindicated after transplant. After one dose…
  • 2018 American Transplant Congress

    Transmission of Rabies through Solid Organ Transplant: A Big Issue in China

    J. Zhang, J. Lin, Y. Tian, L. Ma, W. Sun, L. Zhang, Y. Zhu, W. Qiu, L. Zhang.

    Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

    Purpose To summarize and analyze the clinical characteristic, prophylaxis and treatment of rabies transmitted through solid organ transplant. Methods Four recipients and their donors diagnosed…
  • 2018 American Transplant Congress

    The Clinical Efficacy of Seasonal Influenza Vaccination – Characteristics of Two Outbreaks of Influenza A(H1N1) in Immunocompromised Patients

    I. Helanterä,1 R. Janes,2 V-.J. Anttila.3

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; 2Department of Oncology, Helsinki University Hospital, Helsinki, Finland; 3Department of Infectious Diseases, Helsinki University Hospital, Helsinki, Finland.

    A. Background. Influenza A(H1N1) causes serious complications in immunocompromised patients. The efficacy of seasonal influenza vaccination in transplant recipients and patients receiving chemotherapy has been…
  • 2018 American Transplant Congress

    Impact of Influenza Vaccine Implementation by Transplant Pharmacy in Solid Organ Transplant Recipients

    S. Gattis,1 I. Yildirim,1,2 S. Serluco,1 C. McCracken,2 R. Liverman.1

    1Children's Healthcare of Atlanta, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.

    Background: In solid organ transplant (SOT) recipients, influenza infection can lead to subsequent graft dysfunction and mortality. In an effort to increase vaccination rates, transplant…
  • 2018 American Transplant Congress

    Evaluation of Hepatitis B Vaccination in Transplant Candidates

    M. Bosaeed, Y. AlJishi, S. Husain, C. Rotstein, A. Humar, D. Kumar.

    UHN, Toronto, Canada.

    Background:Hepatitis B virus (HBV) vaccine series is recommended for all organ transplant candidates; high doses of vaccine are generally given to those with renal disease;…
  • 2017 American Transplant Congress

    Successful Implementation of a Pneumococcal Vaccination Program for Pediatric Kidney Transplant Recipients.

    K. Sprott, S. Nadig, K. Twombley.

    Medical University of South Carolina, Charleston

    Vaccine preventable diseases remain a serious problem among transplanted patients. Many children remain under vaccinated after a kidney transplant because of a lack of physician…
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