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Articles tagged "Vaccination"

  • 2021 American Transplant Congress

    Solid Organ Transplant Recipient Attitudes Towards a SARS-CoV-2 Vaccine

    M. Ou1, B. Boyarsky1, L. Zeiser1, T. Chiang1, J. Ruddy1, S. Rasmussen1, J. Martin2, J. Russell2, C. Durand1, R. Avery1, W. Werbel1, M. Cooper3, A. Massie1, D. Segev1, J. Garonzik-Wang1

    1Johns Hopkins, Baltimore, MD, 2National Kidney Foundation, New York, NY, 3Medstar Georgetown Transplant Institute, Washington, DC

    *Purpose: An effective and widely-accepted SARS-CoV-2 vaccine could protect the community and vulnerable populations. We investigated the attitudes of solid organ transplant recipients (SOTRs) towards…
  • 2021 American Transplant Congress

    Development and Durability of Sars-cov-2 Antibodies Among Solid Organ Transplant Recipients

    B. Boyarsky, M. Ou, R. Greenberg, M. Krach, R. Wang, T. P. Chiang, W. Werbel, R. Avery, W. Clarke, A. Tobian, A. Massie, D. Segev, J. Garonzik-Wang

    Johns Hopkins, Baltimore, MD

    *Purpose: The response to SARS-CoV-2 may be blunted in transplant recipients, impacting reinfection risk, treatment selection, and vaccine protocols. We quantified antibody response and durability…
  • 2021 American Transplant Congress

    Attitudes Towards Covid-19 Vaccination in an Inner-city Population of Kidney Transplant Patients (Ktx)

    P. Kerner, A. Imas, G. Udod, L. Gruffi, M. Goldberg, A. Saleh, K. Cruickshank, M. Markell

    SUNY Downstate Health Sciences University, Brooklyn, NY

    *Purpose: Kidney transplant recipients are at high risk for complications from COVID-19 infection and prevention is important. We studied attitudes toward vaccines including willingness to…
  • 2021 American Transplant Congress

    Profile of SARS-CoV-2 Antibodies in Patients Awaiting Kidney Transplantation

    L. Muir1, A. Jaffer2, C. Rees-Spear1, V. Gopalan2, F. Chang2, G. Vaitkute1, R. Fernando3, C. Roustan4, A. Rosa4, C. Earl4, A. Salama2, P. Cherepanov4, L. E. McCoy1, R. Motallebzadeh2

    1Institute of Immunity & Transplantation, University College London, London, United Kingdom, 2Nephrology & Transplantation, Royal Free London Hospital NHS Trust, London, United Kingdom, 3Anthony Nolan Institute, Royal Free London Hospital NHS Trust, London, United Kingdom, 4The Francis Crick Institute, London, United Kingdom

    *Purpose: Patients with end-stage kidney disease (ESKD) represent an extremely vulnerable group with many risk factors for adverse outcomes following SARS-CoV-2 infection. Key questions pertaining…
  • 2021 American Transplant Congress

    Impact of a Pharmacist-driven Immunization Clinic on Vaccination Rates in Pre-liver Transplant Patients

    A. Poparad-Stezar1, B. Summers1, M. Fitzmaurice1, K. Hakamiun2, N. Sulejmani3, A. Jantz1

    1Henry Ford Hospital, Detroit, MI, 2Select Medical, Wyandotte, MI, 3CareDx, Inc., Sterling Heights, MI

    *Purpose: Infectious diseases are a leading cause of morbidity and mortality among patients with end-stage liver disease (ESLD). Vaccination data of ESLD patients pre- and…
  • 2021 American Transplant Congress

    Safety of Sars-cov-2 Mrna Vaccines in Solid Organ Transplant Recipients

    M. Ou, B. Boyarsky, J. Motter, R. Greenberg, A. Teles, J. Ruddy, M. Krach, W. Werbel, R. Avery, A. Massie, D. Segev, J. Garonzik-Wang

    Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: The safety of SARS-CoV-2 mRNA vaccines in solid organ transplant recipients (SOTRs) remains unknown. We investigated adverse events in SOTRs who received these mRNA…
  • 2021 American Transplant Congress

    Limited Immunogenicity of a Single Dose of Sars-cov-2 Mrna Vaccine in Solid Organ Transplant Recipients

    B. Boyarsky, M. Ou, R. Greenberg, A. Teles, W. Werbel, R. Avery, A. Tobian, A. Massie, D. Segev, J. Garonzik Wang

    Johns Hopkins, Baltimore, MD

    *Purpose: Given substantial challenges with vaccine allocation and evidence for short-term vaccine efficacy after a single dose of SARS-CoV-2 mRNA vaccines in clinical trials, some…
  • 2021 American Transplant Congress

    Detection of SARS-CoV-2 Specific Functional T Cells Using a Seven Color Flow Cytometry Assay

    L. Flebbe-Rehwaldt, J. Hayden, K. Mickey, S. Manley, S. Kleiboeker

    Eurofins-Viracor, Lees Summit, MO

    *Purpose: The need to evaluate SARS-CoV-2 immune responses is an important clinical research focus. Detecting neutralizing antibodies is one measure of immune response, but the…
  • 2021 American Transplant Congress

    Adjuvant Treatment Shapes the Bone Marrow Myeloid Compartment Towards an Immunosuppressive Phenotype That Can Suppress Allograft Rejection

    J. Ge1, E. Anderson1, J. F. Markmann2, A. Cuenca1

    1Surgery, Boston Children's Hospital, Boston, MA, 2Surgery, Massachusetts General Hospital, Boston, MA

    *Purpose: Myeloid derived suppressor cells (MDSCs) expand in response to inflammatory stimuli and have been shown to suppress adaptive immunity. Preliminary data from our lab…
  • 2021 American Transplant Congress

    Evaluation of Meningococcal Vaccine Response Among Solid Organ Transplant Recipients Receiving Eculizumab

    R. Arora1, C. Kane1, K. Cunningham1, M. Ison2

    1Pharmacy, Northwestern Memorial Hospital, Chicago, IL, 2Divisions of Infectious Diseases and Organ Transplantation, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Patients receiving eculizumab are at a 1,000-2,000-fold increased risk of invasive meningococcal infections. Therefore, the Advisory Committee for Immunization Practices recommends that these patients…
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