2016 American Transplant Congress
Limiting Helper Functions of CD4 T Cells Improves Efficacy of Induction Therapy without Compromising Responses to Third Party Antigens.
Antibody mediated lymphocyte depletion is commonly used in clinical transplantation. However, memory T cells undermine the efficacy of lymphoablative induction therapies in sensitized transplant recipients.…2016 American Transplant Congress
Nuclear Factor of Activated T-Cells Post-Renal Transplant.
Background: Nuclear Factor of Activated T-cells (NFAT1) is a transcription factor regulating the expression of key targets involved with cellular immune function. Calcineurin is a…2015 American Transplant Congress
Leukocyte Associated Immunoglobulin-Like Receptor 1 inhibits Th1 But Enhances Th17 Responses
Background: Leukocyte Associated Immunoglobulin-like Receptor 1 (LAIR1), is a transmembrane receptor expressed by immune cells. It recognizes collagen repeats via its extracellular domain and has…2015 American Transplant Congress
Th17 Mediates Inflammatory Responses After Lung Transplantation
Background: Long-term outcomes after lung transplantation are markedly worse than for other organs. The mechanisms that determine lung transplant rejection are not clear. The role…2015 American Transplant Congress
BAFF Binding to T Cell-Expressed BAFF-R Promotes Follicular Helper T Cell Proliferation and GC B Cell Responses
Recent studies have defined a crucial role for the B cell–activating factor belonging to TNF family (BAFF) in promoting germinal center (GC) responses in mouse…2015 American Transplant Congress
Immunological Characterization of Full Facial Transplant Recipients
Background: Despite the skin being considered the most immunogenic of all human tissues, full facial transplantation (FFT) has become a life transforming procedure with encouraging…2015 American Transplant Congress
Notch-1 Inhibition Promotes Immune Regulation in Solid Organ Transplantation
Notch receptor signaling plays a key role in T cell activation and differentiation, though limited data exist on its importance in immune regulation. Herein, we…2015 American Transplant Congress
Human Gingival Tissue-Derived Mesenchymal Stem Cells Reduce Murine Acute GVHD Via Killing of Effector CD8+ Cells Through CD39/Adenosine A1R and A2BR Pathways
Human gingival tissue-derived mesenchymal stem cells (GMSCs) are a convenient source of MSCs that have been shown to treat autoimmune disease. Here we use human…2015 American Transplant Congress
Defining and Directing T Cell Subsets Involved in Rejection of Vascularized Composite Allografts
Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.
Purpose: Wider utilization of VCA is hampered by the need for long-term immunosuppression. Barriers to more targeted immunosuppression in VCA include (1) limited knowledge of…2015 American Transplant Congress
Mononuclear Cell Infiltrates Characterization in Scar Tissue from a Bilateral Forearm Transplant Patient: Findings to Think
Herein we report the cell infiltrating pattern in scar tissue resected at the junction of the VCA and the tissue corresponding to the recipient arm,…
- « Previous Page
- 1
- …
- 6
- 7
- 8
- 9
- Next Page »