Articles tagged "T cell reactivity"

2015 American Transplant Congress
Anti-Donor T-Cell Immunity Is a Continuum Immune Process Favouring Subclinical Rejection After Kidney Transplantation
E. Crespo,¹ M. Lucia,¹ J. Cruzado,^1,2 S. Luque,¹ E. Melilli,² A. Manonelles,^1,2 N. Sala,² J. Grinyó,^1,2 O. Bestard.^1,2
¹Experimental Nephrology Laboratory, IDIBELL, Barcelona, Spain; ²Nephrology Department and Renal Transplant Unit, Bellvitge University Hospital, Barcelona, Spain.
Subclinical T-cell mediated rejection (sc-TCR) accounts for a major cause of kidney allograft loss and is unexpectedly found in a rather important number of protocol…
2015 American Transplant Congress
Relative In Vitro Immunoregulatory Effects of Everolimus, Sirolimus, Tacrolimus, Mycophenolic Acid and Drug Combinations
J. Mathew, X. Huang, J. Leventhal, L. Gallon, J. Miller, J. Levitsky.
Surgery - Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.
Everolimus (EVL) is a modified form of the mTOR-inhibitor Sirolimus (SRL) and is used clinically in combination with Mycophenolate (MMF) and/or Tacrolimus (TAC). The purpose…
2015 American Transplant Congress
IgM+ Antigen Binding B Cells in Peripheral Blood Regulate IFNγ Production in Response to HLA Proteins
L. McLaughlin,¹ K. Shiu,¹ G. Lombardi,¹ J. Spencer,² R. Vaughan,¹ A. Dorling.¹
¹MRC Centre for Transplantation, King's College London, London, United Kingdom; ²Peter Gorer Department of Immunobiology, King's College London, London, United Kingdom.
Chronic antibody mediated rejection (CAMR) is a major cause of graft loss in renal transplant recipients. Previous work utilising an IFNγ ELISPOT assay revealed two…