ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Articles tagged "T cell reactivity"

  • 2020 American Transplant Congress

    Non-Human Primate B Cells Into Regulatory B Cells by Activation with CpG

    K. Lee1, C. Rickert1, K. Deng1, N. Feeney1, N. Tanimine2, Q. Fu1, G. Huai1, J. Lei1, C. Leguern1, J. Markmann1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Gastroenterological Transplantation Surgery, Hiroshima University, Hiroshima, Japan

    *Purpose: We previously generated Toll like receptor (TLR)-activated B cells in rodent settings. These B cells can suppress T cell proliferation via in vitro mixed…
  • 2020 American Transplant Congress

    Evaluating Preformed Donor HLA Reactive T Cells Using PIRCHE-II Algorithm

    T. Tomosugi1, K. Iwasaki2, S. Sakamoto1, A. Kanda1, K. Futamura1, M. Okada1, T. Hiramitsu1, N. Goto1, S. Narumi1, Y. Watarai1, T. Kobayashi2, M. Niemann3, E. Spierings4

    1Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan, 2Kidney Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan, 3PIRCHE AG, Berlin, Germany, 4University Medical Center Utrecht, Utrecht, Netherlands

    *Purpose: De novo donor-specific HLA antibodies (dnDSA) production involves the indirect allorecognition pathway in which recipient CD4+T cells recognize donor-HLA-derived peptide and recipient HLA class…
  • 2020 American Transplant Congress

    Autophagy-Lysosome Inhibitor Chloroquine Prevents CTLA-4 Degradation of T Cells and Attenuates Acute Rejection in Murine Skin and Heart Transplantation

    J. Wu

    Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    *Purpose: The immune checkpoint cytotoxic T lymphocyte antigen-4 (CTLA-4), which was induced upon T cell activation but degraded quickly, has been targeted in the clinical…
  • 2020 American Transplant Congress

    Prospective Donor-Specific CellUlar Alloresponse Assessment for Immunosuppression MinImization in De Novo Renal Transplantation: Results of a Randomized Controlled Biomarker-Guided Trial

    O. Bestard1, P. Reinke2, F. Bemelman3, O. Viklicky4, M. Koch5, M. Giral6, J. Ruiz7, B. Banas8, E. Crespo1, M. Meneghini1, H. Volk9, J. Grinyo1

    1Kidney transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, 2Kidney transplantation Unit, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Kidney transplantation Unit, Amsterdam Medical Centre, Amsterdam, Netherlands, 4Nephrology department, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, 5Department of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 6Nephrology, Kidney transplantation Unit, Université de Nantes, Nantes, France, 7Nephrology, Hospital Marques de Valdecilla, Santander, Spain, 8Kidney transplantation Unit, University Hospital Regensburg, Regensburg, Germany, 9Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

    *Purpose: Early immunosuppression minimization is associated with higher rates of BPAR. Preformed donor-specific T-cell alloreactivity (DST) assessed with an IFN-γ ELISPOT assay has shown to…
  • 2020 American Transplant Congress

    Successful Tacrolimus Withdrawal in Kidney Transplant Recipients Unleashes a Peripheral Blood Transcriptional and Functional Signature Resembling Exhaustion

    P. Cravedi, M. Fribourg, S. Harztell, L. Anderson, P. Heeger

    Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: Tacrolimus (Tac) is an effective anti-rejection drug in kidney transplant recipients (KTR), but its off-target effects make withdrawal desirable. Studies indicate that Tac can…
  • 2020 American Transplant Congress

    Novel Flow-Based Assay to Detect Allospecific T Cells in Transplantation Study

    N. Tanimine1, B. E. Burrel2, J. Pardo2, C. Rickert3, K. M. Lee3, K. Deng3, N. Feeney3, C. Leguern3, J. F. Markmann3

    1Department of Gastroenterological and Transplantation Surgery, Hiroshima University, Hiroshima, Japan, 2Immune Tolerance Network, Bethesda, MD, 3Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    *Purpose: Identifying and phenotyping donor-reactive T cells in recipients following transplantation may further the understanding of interactions between the recipient’s immune system and donor antigen.…
  • 2020 American Transplant Congress

    Neonatal Tolerance Induction: Behaviours of Allogeneic Spleen and Bone Marrow Inocula in Neonatal Mice are Largely Determined by the Nature of Their CD8 T Cells

    R. A. Bascom, K. Tao, L. J. West

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Injected adult allo-spleen (SC) and bone marrow cells (BMC) traffic to secondary lymphoid organs, proliferate and spread throughout neonatal mice; allo-SC consistently cause acute…
  • 2019 American Transplant Congress

    Regulating T Cell Responses by Forced Transgenic Expression of Decay-Accelerating Factor

    D. Heja1, Z. He1, S. A. Lira1, F. Lin2, D. Homann1, P. S. Heeger1

    1Icahn School of Medicine at Mount Sinai, New York, NY, 2Cleveland Clinic, Cleveland, OH

    *Purpose: Decay-accelerating factor (DAF, CD55) is a cell surface expressed, glycophosphatidylinositol-(GPI)-anchored, complement regulator. Previous studies showed that during cognate T cell/antigen presenting cell (APC) interactions…
  • 2019 American Transplant Congress

    First Report and Mechanistic Analysis of Operational Tolerance after Intestinal Transplant

    J. Weiner1, S. Moturi1, C. Ashokkumar2, K. Khan1, S. Kaufman1, R. Sindhi2, C. Matsumoto1, T. Fishbein1, A. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2University of Pittsburgh, Pittsburgh, PA

    *Purpose: Transplantation tolerance is a highly sought and rarely achieved state in clinical medicine. Defined as long-term stable and acceptable graft tolerance without immunosuppression and…
  • 2019 American Transplant Congress

    MDSCs Prolong Allogeneic Cardiac Graft Survival by Regulating Interferon Type 1 Signaling

    S. Cai1, P. T. Sage1, T. J. Borges1, T. Ichimura1, S. K. Eskandari1, J. Y. Choi1, I. Salkuj1, B. S. AI Dulaijan1, H. Allos1, J. Miao2, L. V. Riella1, A. K. Chandraker1, J. R. Azzi1

    1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Boston Children's Hospital, Harvard Medical School, Boston, MA

    *Purpose: We previously demonstrated that donor-derived regulatory dendritic cells (DCreg), contrary to recipient derived DCreg, promote antigen-specific allograft protection. As myeloid-derived suppressor cells (MDSC) show…
  • 1
  • 2
  • 3
  • …
  • 7
  • Next Page »

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use

This site uses cookies: Find out more.