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Articles tagged "T cell graft infiltration"

  • 2015 American Transplant Congress

    CD3+CD4+ROR gamma t+ TH17 Cells Do Not Play a Critical Role in Islet Allograft Rejection

    M. Koulmanda, Z. Fan.

    Medicine, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA.

    We have developed a “color-coded” adoptive transfer model for T cell subset identification that enables serial analysis of islet allograft infiltrating yellow induced regulatory T…
  • 2015 American Transplant Congress

    Effector T Cell Migration to Pancreatic Islet Allografts Is Dependent On Donor Antigen Recognition and Not Gαi Chemokine Signaling

    Q. Zhang, H. Dai, Q. Zeng, A. Williams, M. Oberbarnscheidt, F. Lakkis.

    Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA.

    Infiltration of the graft with host effector T cells after transplantation is a key step in the pathogenesis of both acute and chronic rejection. Recent…
  • 2015 American Transplant Congress

    Immunological Aspects of Iron Overload in Heart and Kidney Transplantation

    T. Resch,1 S. Ebner,1 P. Ritschl,1 M. Ashraf,1 C. Fabritius,1 A. Brunner,2 V. Nguyen,1 J. Günther,1 J. Pratschke,3 K. Kotsch.1

    1Department of Surgery, Medical University Innsbruck, Innsbruck, Austria; 2Department of Pathology, Medical University Innsbruck, Innsbruck, Austria; 3Department of Surgery, Charité, Berlin, Germany.

    Background: Clinical data suggest that iron (Fe) overload deleteriously affects graft survival after heart (HTX) and kidney transplantation (KTX) but possible immunologic mechanisms underlying this…
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