Articles tagged "T cell graft infiltration"

2015 American Transplant Congress
Not Only CD28null But Also CD28pos T Cells Contribute to Rejection During Belatacept Treatment
G. de Graav,¹ D. Hesselink,¹ R. Kraaijeveld,¹ M. Dieterich,¹ W. Weimar,¹ M. Clahsen-Van Groningen,² C. Baan.¹
¹Internal Medicine, Erasmus Medical Center, Rotterdam, South Holland, Netherlands; ²Pathology, Erasmus Medical Center, Rotterdam, South Holland, Netherlands.
To explain the underlying immunological mechanisms for rejection under belatacept treatment, the phenotypical and functional characteristics of graft infiltrating lymphocytes were studied during rejection under…
2015 American Transplant Congress
Bidirectional Regulation and IL35 Surface Expression By Treg Cells
Y. Tomita, W. Burlingham.
Surgery, University of Wisconsin, Madison, WI.
Background: Pre-transplant regulation on the donor side(toward the recipient), as well as the recipient side(toward the donor) promotes long-term graft survival of a kidney allo-graft…
2015 American Transplant Congress
Cellular Mechanism of Enhanced Alloimmunity by Ischemia Reperfusion Injury
Z. Solhjou, M. Uehara, S. Ohori, M. McGrath, J. Azzi, S. Tullius, R. Abdi.
Transplant Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Ischemia reperfusion injury of transplanted organs represents a key pathogenic inflammatory process, which increases their allogenicity; subsequently augmenting the rate of acute and chronic rejection.…