2015 American Transplant Congress
Evaluating Outcomes in Multi-Organ Liver Transplant Recipients
Historically, transplant (Tx) program evaluations performed by the Scientific Registry of Transplant Recipients (SRTR) in the US have included only single-organ Txs, except for simultaneous…2015 American Transplant Congress
Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation
Transplant Institute, Georgetown University Hospital, Washington, DC.
IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…2015 American Transplant Congress
Activated T Regulatory Cells Escape Death by Increasing Cytoplasmic Serine Protease Inhibitor 6 (SPI6)
Renal/ Transplantation Research Center, Brigham and Women's Hospital, Boston, MA.
Regulatory T cells (Tregs) can employ a granzyme B (GrB)-dependent mechanism to mediate suppression of effector cells by inducing their apoptosis. In this study we…2015 American Transplant Congress
The Impact of Acute Rejection on Liver Transplant Survival in the New Millennium
Background: Based on pre-2000 data, acute rejection (AR) has long been considered clinically less significant in liver transplant (LT) vs. other organ recipients (Charlton et…2015 American Transplant Congress
Establishment of a Novel Model for Hypothermic Machine Perfusion In Vivo in Rabbits
Background: Hypothermic machine perfusion (MP) could improve outcome after transplantation of DCD kidneys, but protective mechanisms of MP remain largely unknown. Therefore, this study aims…2015 American Transplant Congress
Does BMI Affect Survival in Cadaveric Liver Transplantation for Benign Conditions?
Surgery, Dalhousie University, Halifax, NS, Canada.
Obesity is a relative contraindication to liver transplantation (LT). Aim of this study was to analyze morbidity, mortality, long-term survival of cadaveric LTs stratified by…2015 American Transplant Congress
Stimulating Protease Inhibitor 9 Expression By Human Regulatory T Cells Improve Homeostasis
Renal/ Transplantation Research Center, Brigham and Women's Hospital, Boston, MA.
In this study, we show for the first time the key role of a protease inhibitor PI9 in human regulatory T cells (Tregs) homeostasis. Recent…2015 American Transplant Congress
Rabbit Antithymocyte Globulin Is Associated With Improved Patient and Graft Survival in Liver Transplantation. Experience With 595 Patients
BACKGROUND: Use of induction therapy in liver transplantation is debatable. We aimed to compare clinical outcomes of different induction protocols in liver transplant recipients.METHODS: Retrospective…2015 American Transplant Congress
Proteinuria as Non-Invasive Marker for Renal Allograft Histology and Survival: A Population-Based Study
University Hospitals Leuven, Leuven, Belgium.
Background:Proteinuria is routinely measured for assessment of renal allograft status, but its diagnostic value for transplant pathology and herewith-related prognostic value remain unclear.Methods:We included 1518…2015 American Transplant Congress
U.S. National Experience of Liver Transplantation Using Allografts from Octogenarian Donors
Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.
IntroductionA continuous worsening of donor organ shortage has led to expand organ acceptance criteria. It is still theoretically possible to utilize hepatic allografts from donors…
American Transplant Congress abstracts