Articles tagged "Survival"

2016 American Transplant Congress
Outcomes of Solid Organ Transplant Recipients with Pre-Existing Malignancies.
S. Acuna,^1,2,3 R. Sutradhar,^1,2 J. Kim,^1,2,4 N. Baxter.^1,2,3
¹Institute of Health Policy, Management and Education, University of Toronto, Toronto, ON, Canada; ²Institute of Clinical Evaluative Sciences, Toronto, ON, Canada; ³Department of Surgery, St. Michael's Hospital, Toronto, ON, Canada; ⁴Department of Medicine, University Health Network, Toronto, ON, Canada.
Background: Pre-transplant malignancy (PTM) is considered a relative contraindication for transplantation due to the heightened risk of cancer recurrence associated with immunosuppression. However, little has…
2016 American Transplant Congress
Aquaporin 4 Blockade Is a Novel Strategy to Prevent T Cell Activation and Effector Functions.
K. Ayasoufi,¹ N. Kohei,¹ G. Farr,² P. McGuirk,² M. Pelletier,² R. Fairchild,¹ A. Valujskikh.¹
¹Cleveland Clinic, Cleveland; ²Aeromics LLC, Cleveland.
Aquaporin 4 (AQP4) belongs to the family of integral transmembrane proteins highly permeable to water. We have previously reported that blocking AQP4 with small molecule…
2016 American Transplant Congress
Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.
M. Khan,¹ H. El-Hennawy,¹ J. Rogers,¹ A. Farney,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC.
Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…
2016 American Transplant Congress
Donor Smoking Increases Kidney Allograft Recipient Mortality in a National Population Cohort Analysis.
H. Gillott,¹ F. Jackson-Spence,¹ S. Tahir,¹ F. Evison,² J. Nath,³ A. Sharif.³
¹Medical School, University of Birmingham, Birmingham, United Kingdom; ²Medical Informatics, Queen Elizabeth Hospital, Birmingham, United Kingdom; ³Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Introduction: Current evidence from single-centre analyses suggest cigarette smoking in living donors is associated with worse patient but not graft survival in kidney allograft recipients.…
2016 American Transplant Congress
Graft Survival in Sensitized and Non-Sensitized Patients: Role of the Combination of Donor-Specific Antibodies and Acute Rejection.
P. Souza,¹ A. Aguirre,¹ G. Bezerra,² H. Rodrigues,² F. Agena,¹ D. David,¹ F. de Paula,¹ E. David-Neto,¹ M. Castro.¹
¹Renal Transplant Service, Hospital das Clínicas de São Paulo, Sao Paulo, Brazil; ²Immunology Laboratory, Instituto do Coração (InCor), Sao Paulo, Brazil.
Background: Sensitized (S) patients have higher risk for acute rejection (AR), especially ABMR. DSA is a risk fator for ABMR, however, its impact on AR…
2016 American Transplant Congress
Hematopoietic Cell Transplant and Solid Organ Transplantation: A First Report of the U.S. Experience.
M. Gupta, M. Levine, P. Abt.
Surgery, Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA.
The prevalence of patients who receive both a hematopoetic cell(HCT) and solid organ transplantation(SOT) is rising. There have been no large scale studies of HCT…
2016 American Transplant Congress
Pre-Transplant Infusion of Extracorporeal Photopheresis Treated Donor Splenocytes Leads to Long-Term Liver Allograft Survival and Donor Specific Tolerance in Rats.
X. Kang,¹ Y. Xie,² X. Yeap,² J. Wang,² J. Schneiderman,² Z. Zhang.²
¹Hepatopancreatobiliary Surgery, The Third Hospital of Jilin University, Changchun, Jilin, China; ²Comprehensive Transplant Center, Northwestern University Feinberg School of Medicin, Chicago, IL.
Extracorporeal photopheresis (ECP), a procedure that exposes isolated WBC to photoactivatable 8-methoxypsoralen and ultraviolet A radiation, is used clinically to treat patients with cutaneous T-cell…
2016 American Transplant Congress
An Analysis of Factors Associated with Pancreas Allograft Thrombosis.
J. Steggerda, K. Bornhurst, A. Annamalai, A. Peng, J. Mirocha, D. Dafoe.
Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
A successful simultaneous pancreas-kidney (SPK) transplant in recipients with end-stage diabetic nephropathy will provide normoglycemia and exert a salutary effect on neurovascular complications. Early, non-technical…
2016 American Transplant Congress
Using Gastrointestinal Biopsy to Predict Outcome in Patients Evaluated for Cardiac Transplantation for Amyloidosis: A Report from the International Consortium on Cardiac Amyloidosis Transplantation (iCCAT).
Y. Li,¹ K. Verkouw,¹ S. Tabtabai,¹ R. Barrios,² R. Gill,³ J. Koo,⁴ C. Marboe,⁵ E. Rodriguez,⁶ C. Tan,⁶ T. De Marco,³ J. Estep,² M. Hanna,⁶ M. Maurer,⁵ J. Patel,⁴ V. Selby,³ M. Semigran,¹ J. Stone.¹
¹Massachusetts General Hospital, Boston, MA; ²The Methodist Hospital, Houston, TX; ³University of California San Francisco, San Francisco, CA; ⁴Cedars-Sinai Heart Institute, Los Angeles, CA; ⁵Columbia University Medical Center, New York, NY; ⁶Cleveland Clinic, Cleveland, OH.
Heart transplant (HT) is an established therapy for heart failure due to amyloidosis. The utility of gastrointestinal (GI) biopsy in predicting patient outcomes and guiding…
2016 American Transplant Congress
Chimeric Cell Transplantation for Treatment of Duchenne Muscular Dystrophy: A Preliminary Report.
E. Szilagyi, E. Bryndza Tfaily, J. Cwykiel, M. Siemionow.
Orthopaedic Surgery, University of Illinois at Chicago, Chicago.
Background: Transplant of Chimeric Cells, created via ex vivo fusion of donor and recipient cells, represents a promising cell therapy option in the field of…