Articles tagged "Survival"

2016 American Transplant Congress
Predicting the Timing of Graft Failure in De Novo DSA Positive Patients.
M. Everly,¹ L. Rebellato,² C. Haisch,² K. Briley,² P. Bolin,² S. Kendrick,³ C. Morgan,² A. Maldonado,⁴ A. Nguyen,¹ P. Terasaki.¹
¹Terasaki Foundation Laboratory, Los Angeles; ²East Carolina University, Greenville, NC; ³Eastern Nephrology Associates, Greenville, NC; ⁴Vidant Medical Center, Greenville, NC.
The risk of graft failure after de novo DSA (dnDSA) is not always immediate. To make more informed therapeutic decisions in dnDSA+ patients, we need…
2016 American Transplant Congress
Does Pre-Emptive Transplantation Improve Survival Compared to Transplantation After Dialysis Among Deceased Donor Kidney Recipients?
J. Tao, C. Wu, W. Bannister, M. Schnitzler, A. Bonagura, B. Laihinen, F. Irwin.
Complex Medical Conditions, Optum, UnitedHealth Group, Eden Prairie, MN; Surgery, St Louis University, St Louis, MO.
Previous studies have shown that pre-emptive transplantation of kidneys from living donors is associated with longer graft survival than those who have initiated dialysis prior…
2016 American Transplant Congress
Robotic Kidney Transplantation in Obese Recipients Can Lead to Superior Outcomes in Terms of Wound Infection and Graft Survival – 48 Months of Follow-up.
I. Tvetanov, S. Garcia Aroz, M. Spaggiari, J. Hoonbae, J. Oberholzer, E. Benedetti.
Surgery, University of Illinois, Chicago, IL.
Introduction: Traditionally kidney transplantation (KT) in obese recipients has been associated with high rates of surgical site infections (SSI). We hypothesize that robotic kidney transplantation…
2016 American Transplant Congress
Outcomes of Isolated Pediatric Small Intestine Transplants Using Vascular Homografts.
Y. Kwon, N. Llore, R. Girlanda, K. Etesami, C. Desai, C. Matsumoto, T. Fishbein.
MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC.
Background/aim: Pediatric intestinal transplantation has changed recently with more isolated small intestine transplants being performed in small children instead of combined liver-intestine transplants. Consequently, surgical…
2016 American Transplant Congress
T-Bet Regulates nTreg Stability and Suppression in an Islet Allograft Model.
Y. Xiong, S. Ahmad, D. Iwami, C. Brinkman, J. Bromberg.
University of Maryland, Baltimore.
The transcription factor T-bet endows Treg with properties tosuppress Th1 inflammation. However, the mechanisms by which T-bet controls alloimmune responses are not fully understood. We…
2016 American Transplant Congress
Simulating Alternative Bayesian Criteria to Identify Transplant Center Performance Outliers.
J. Schold,¹ C. Miller,¹ M. Henry,² L. Buccini,¹ S. Flechner,¹ D. Goldfarb,¹ E. Poggio,¹ K. Andreoni.³
¹Cleveland Clinic, Cleveland, OH; ²Ohio State University, Columbus, OH; ³University of Florida, Gainesville, FL.
The newly constructed Bayesian models to evaluate transplant center performance were implemented in 2014. The rates and impact of the assumptions used for flagging centers…
2016 American Transplant Congress
Survival Benefit of Kidney Transplantation in US Adults with Sickle Cell Nephropathy.
T. Purnell, X. Luo, S. Bae, A. Massie, D. Segev.
Johns Hopkins, Baltimore.
End-stage renal disease (ESRD) patients with sickle cell nephropathy (SCN) are less likely to receive a kidney transplant (KT) than ESRD patients without SCN. Comparing…
2016 American Transplant Congress
Impact of C3d and C1q-Binding DSA Detected Long-Term After Kidney Transplantation.
M. Crespo,^1,2 D. Redondo,^1,2 C. Garcia,³ J. Gimeno,⁴ M. Perez,^1,2 M. Mir,¹ J. Hernandez,³ J. Yelamos,² A. Faura,^1,2 J. Pascual.^1,2
¹Nephrology and Transplant, Hospital del Mar, Barcelona, Spain; ²Medical Research Institute (IMIM), Hospital del Mar, Barcelona, Spain; ³Catalunya Reference Laboratory, Barcelona, Spain; ⁴Pathology, Hospital del Mar, Barcelona, Spain.
HLA DSA detected after kidney transplantation(KT) correlate with outcome, but not all are equal and produce the same functional consequences. Early complement-binding DSA were asssociated…
2016 American Transplant Congress
Outcomes of Solid Organ Transplant Recipients with Pre-Existing Malignancies.
S. Acuna,^1,2,3 R. Sutradhar,^1,2 J. Kim,^1,2,4 N. Baxter.^1,2,3
¹Institute of Health Policy, Management and Education, University of Toronto, Toronto, ON, Canada; ²Institute of Clinical Evaluative Sciences, Toronto, ON, Canada; ³Department of Surgery, St. Michael's Hospital, Toronto, ON, Canada; ⁴Department of Medicine, University Health Network, Toronto, ON, Canada.
Background: Pre-transplant malignancy (PTM) is considered a relative contraindication for transplantation due to the heightened risk of cancer recurrence associated with immunosuppression. However, little has…
2016 American Transplant Congress
Aquaporin 4 Blockade Is a Novel Strategy to Prevent T Cell Activation and Effector Functions.
K. Ayasoufi,¹ N. Kohei,¹ G. Farr,² P. McGuirk,² M. Pelletier,² R. Fairchild,¹ A. Valujskikh.¹
¹Cleveland Clinic, Cleveland; ²Aeromics LLC, Cleveland.
Aquaporin 4 (AQP4) belongs to the family of integral transmembrane proteins highly permeable to water. We have previously reported that blocking AQP4 with small molecule…