Articles tagged "Survival"

2019 American Transplant Congress
Recipient TIM4 Expression is Essential for Hepatocellular Function in Liver Transplantation
K. Kadono, S. Kageyama, H. Hirao, K. Nakamura, K. J. Dery, D. Oncel, T. Ito, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor of early graft dysfunction and predisposes to rejection in orthotopic liver transplantation (OLT). Previous studies…
2019 American Transplant Congress
Reduced Intensity Induction Therapy in Patients Undergoing Repeat Kidney Transplants
K. Linhares, M. Cristelli, C. Felipe, L. Viana, H. Proença, R. E. de Marco, J. Pestana, H. Tedesco
Hospital do Rim, Nephrology Division, EPM - UNIFESP, São Paulo, Brazil
*Purpose: We hypothesized that patients without donor-specific antibodies (DSA) undergoing repeat transplants could receive lower doses of antithymocyte globulin induction (rATG), without compromising efficacy and…
2019 American Transplant Congress
Dendritic Cells Transduced with Autoimmune Regulator Exhibit Immature Properties and Prolong Heart Allograft Survival
Y. Zhang, Z. Zhu, M. Chen, S. Huang, C. Sun, W. Ju, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: The expression of the Aire (Autoimmune regulator) gene was observed to inhibit the maturation and activation of dendritic cells (DCs) and induce transplantation tolerance.*Methods:…
2019 American Transplant Congress
Vo_2peakSuperior to Current Established Measure of Post Kidney Transplant Survival Score (EPTS Score)
H. Chakkera¹, R. Butterfield¹, M. Buras¹, B. Kaplan²
¹Mayo Clinic Hospital, Phoenix, AZ, ²Baylor Scott and White, Dallas, TX
*Purpose: The Scientific Registry of Transplant Recipients (SRTR) utilizes the calculated estimated posttransplant survival (EPTS) score as the measure of post kidney transplant survival to…
2019 American Transplant Congress
Global Analysis of Fc-gamma Receptors Binding Capacity of Human Leukocyte Antigen Donor Specific Antibody
E. S. Woodle, A. Girnita
University of Cincinnati Academic Health Center, Cincinnati, OH
*Purpose: Functional assessment of anti-HLA antibodies has historically been limited to complement-binding assays. However, antibodies are capable of inducing injury by complement-independent mechanisms, including Fc-gamma…
2019 American Transplant Congress
Leukopenia in Older Kidney Transplant Recipients is Associated with Decreased Allograft Survival and Increased Patient Survival
R. Rodriguez, A. Price, K. Soliman, R. Vinaya, D. Lazarus, M. Casey, M. Labonte, L. Erbe, M. Shearer, D. Taber, M. Posadas Salas
Transplant Nephrology, Medical University of South Carolina, Charleston, SC
*Purpose: Older kidney transplant recipients are vulnerable to side effects of immunosuppression (IS) including leukopenia. Providers often reduce MMF dose in response to leukopenia. This…
2019 American Transplant Congress
Outcomes of Liver Transplantation for Hepatocellular Carcinoma in Septuagenarians
M. Najjar¹, K. Bruestle¹, P. Jiang¹, E. Lieberman¹, R. Hwang¹, A. Mathur¹, E. C. Verna¹, A. Griesemer¹, B. Samstein², T. Kato¹, Y. M. Saenger¹, K. J. Halazun², J. C. Emond¹
¹Columbia University Medical Center, New York, NY, ²Weill Cornell Medicine, New York, NY
*Purpose: The impact of advanced age on liver transplantation (LT) for hepatocellular carcinoma (HCC) has not been well studied. We sought to compare post-OLT survival…
2019 American Transplant Congress
Diminishing Scientific Registry of Transplant Recipients Risk-Adjusted Mortality: Reaction to Flagging, Artifact of Modeling, or Both?
J. A. Gregg¹, K. L. Womer¹, A. Santos¹, S. J. Moore², K. A. Andreoni³
¹Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL, ²Shands Transplant Center, University of Florida, UF Health Shands, Gainesville, FL, ³Department of Surgery, University of Florida, Gainesville, FL
*Purpose: To examine longitudinal trends in SRTR risk-adjusted patient and graft survival rates.*Methods: Current, and archived versions of The Scientific Registry of Transplant Recipients (SRTR)…
2019 American Transplant Congress
Aorto-Iliac Calcification is a Risk Factor for Inferior Patient and Graft Survival in Kidney Transplant Recipients; A Systematic Review and Meta-Analysis
A. A. Rijkse, J. L. van Dam, H. J. Kimenai, J. N. IJzermans, R. C. Minnee
HPB/Transplant surgery, Erasmus Medical Center, Rotterdam, Netherlands
*Purpose: While the incidence of transplanting a kidney onto atherosclerotic iliac arteries is becoming more common, little is known about the clinical outcome. We performed…
2019 American Transplant Congress
Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts
I. Linares-Cervantes¹, J. Echeverri¹, S. Cleland¹, M. Kaths¹, R. Rosales¹, T. Goto¹, D. Kollmann¹, M. Hamar¹, P. Urbanellis¹, L. Mazilescu¹, S. Ganesh¹, O. Adeyi¹, P. Yip¹, B. Bojko², P. Gorynzka², K. Gorynski², D. Grant¹, N. Selzner¹, M. Wasowicz¹, M. Selzner¹
¹Toronto General Hospital, Toronto, ON, Canada, ²University of Nicolaus Copernicus, Torun, Poland
*Purpose: Evaluate parameters of liver viability during normothermic ex-situ liver perfusion (NEsLP) prior to transplantation.*Methods: In this study, we investigated prior assessed parameters and new…