Articles tagged "Survival"

2020 American Transplant Congress
Low Physiochemical Immunogenicity Scores Improve Long-Term Survival of Deceased Donor Kidney Transplants
D. Bekbolsynov¹, B. Mierzejewska¹, J. Borucka², S. A. Khuder¹, M. Rees¹, R. Green³, S. Stanislaw¹
¹University of Toledo, Toledo, OH, ²Parexel Corp., Warsaw, Poland, ³Bowling Green State University, Bowling Green, OH
*Purpose: A severe shortage of deceased donor kidneys limits access to kidney transplantation. Limited longterm graft function exacerbates this shortage as 12% of the waiting…
2020 American Transplant Congress
The Living Donor Collective Pilot Evaluations of Living Kidney Donor Candidates at 10 Programs
B. Kasiske, M. Conboy, Y. Ahn, A. Israni, J. Snyder
SRTR, Minneapolis, MN
*Purpose: Much remains to learn regarding long-term effects of living organ donation on donors. Rare events are important, and long-term follow-up with appropriate contemporaneous controls…
2020 American Transplant Congress
Optimal Transition for Transplant Recipients: A Model of Care in an Integrated Health Care System
S. Zheng¹, L. Pravoverov¹, A. Nazarova¹, D. Adey², N. B. Goes¹
¹The Permanente Medical Group, San Francisco, CA, ²Kidney and Transplantation Program, University of California San Francisco, San Francisco, CA
*Purpose: Transplantation is the treatment of choice for ESRD. While short-term outcomes have improved, long-term outcomes lag. Many factors may explain the long-term lag including…
2020 American Transplant Congress
Results of Pancreas Transplantation in Diabetic Patients with End-Stage Kidney Disease Older Than 50 Years
E. Montagud-Marrahi¹, A. Molina², A. Pané³, M. Ramirez-Bajo⁴, A. Amor³, E. Esmatjes³, J. Ferrer⁵, F. Diekmann¹, P. Ventura-Aguiar¹
¹Nephrology and Kidney Transplantation Department, Hospital Clínic de Barcelona, Barcelona, Spain, ²Servei de Nefrologia i Trasplantament Renal, Hospital Clínic de Barcelona, Barcelona, Spain, ³Endocrinology Department, Hospital Clínic de Barcelona, Barcelona, Spain, ⁴Laboratori Experimental de Nefrologia I Trasplantament (LENIT), CRB CELLEX, Fundació Clínic, IDIBAP, Hospital Clínic de Barcelona, Barcelona, Spain, ⁵Hepatobiliopancreatic and Liver Transplant Department, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: Improvement of care in type 1 diabetes mellitus, with the optimization of patient access to insulins of variable action, has led to macro- and…
2020 American Transplant Congress
Heart Transplant Outcomes for Patients with Left Ventricular Assist Devices (LVAD) Before and after the 2018 Revision of the United Network for Organ Sharing (UNOS) Adult Heart Allocation System
J. Pizula¹, K. Yang¹, J. Li¹, S. Shah¹, G. Liu¹, A. Lee¹, P. Banankhah¹, J. Nattiv¹, D. Miklin¹, P. Genyk¹, P. Kingsford¹, K. Pandya¹, R. Joeseph¹, M. Fong¹, G. Luanda¹, A. Kiankhooy¹, S. Hashmi¹, S. Nuno¹, A. Wolfson², A. Salimbangon³, R. Chand⁴, D. Vucicevic⁵, L. Corey⁶, E. Depasquale¹, A. Vaidya¹
¹Cardiology, LAC-USC, Los Angeles, CA, ²University of Arizona Sarver Heart Center, Tuscon, AZ, ³UCLA Medical Center, Los Angeles, CA, ⁴Harbor-UCLA Medical Center, Los Angeles, CA, ⁵Newark Beth-Israel Medical Center, Newark, NJ, ⁶The Queen's Medical Center, Honolulu, HI
*Purpose: In October of 2018 UNOS chaged their adult heart allocation criteria to address disparity in waiting list survival. The implications of this policy change…
2020 American Transplant Congress
Tracking Tregs in a Non-Human Primate Model with Expanded Autologous Treg Infusions In Vivo
K. Bruestle¹, B. Piegari¹, H. Sakai¹, F. Fredriksson¹, D. Ekanayake-Alper¹, S. Robertson², D. Hajosi², J. Weiner¹, A. Iuga³, S. M. Coley³, M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Institute for Comparative Medicine, Columbia University, New York City, NY, ³Department of Pathology and Cell Biology, Columbia University, New York City, NY
*Purpose: Regulatory Tcell (Treg) therapy is a promising tool for tolerance induction in solid organ transplantation. Despite encouraging results in humans and monkeys, questions about…
2020 American Transplant Congress
Proposed New Kidney Allocation Policy: Moving to Concentric Circles as the First Unit of Allocation
A. Israni¹, S. Gustafson¹, A. Wey¹, B. Thompson¹, V. Casingal², M. Pavlakis³, S. Castro⁴, A. Wilk⁴, B. Kasiske¹, J. Snyder¹
¹SRTR, Minneapolis, MN, ²Carolinas Healthcare, Charlotte, NC, ³Beth Israel Deaconess, Boston, MA, ⁴UNOS, Richmond, VA
*Purpose: The Organ Procurement and Transplantation Network (OPTN) proposed a new national deceased donor kidney allocation policy that removes donor service area and OPTN region…
2020 American Transplant Congress
Living Donor Liver Transplantation Demonstrated Superiority to Deceased Donor Transplantation after Adult-To-Adult Liver Transplantation in Cumulative Single-Center Retrospective Cohort Study of 19 Years
T. Goto, T. Reichman, G. Sapisochin, I. McGilvray, M. Selzner, A. Ghanekar, M. Cattral, N. Selzner
Multi-Organ Transplant Program, Toronto General Hospital, Institute of Medical Science, University of Toronto, Toronto, ON, Canada
*Purpose: Living donor liver transplantation (LDLT) is an alternative way to deceased donor liver transplantation (DDLT). LDLT and DDLT showed similar short-term outcomes of recipient…
2020 American Transplant Congress
Cytomegalovirus Infection and Outcomes in Pancreas Transplant Recipients in the Prophylaxis Era
M. Jorgenson¹, N. Marka², G. Leverson², J. Smith², J. Odorico²
¹UW Health, Madison, WI, ²UWMF, Madison, WI
*Purpose: Evaluate epidemiology and outcomes of cytomegalovirus infection (CMV) in pancreas transplant recipients (PTR) in the current era of valganciclovir (VGC) prophylaxis (PPX)*Methods: Adult PTRs…
2020 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Future Proteinuria
S. Jordan¹, P. Sood², J. Bromberg³, D. Brennan⁴
¹Cedars-Sinai, Los Angeles, CA, ²University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Maryland, Baltimore, MD, ⁴The Johns Hopkins Hospital, Baltimore, MD
*Purpose: Most allografts with proteinuria >1500 mg/dL have new glomerular pathology. In contrast, lower levels of proteinuria are generally associated with non-glomerular, nonspecific histologic changes.…