Articles tagged "Survival"

2020 American Transplant Congress
Tracking Tregs in a Non-Human Primate Model with Expanded Autologous Treg Infusions In Vivo
K. Bruestle¹, B. Piegari¹, H. Sakai¹, F. Fredriksson¹, D. Ekanayake-Alper¹, S. Robertson², D. Hajosi², J. Weiner¹, A. Iuga³, S. M. Coley³, M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Institute for Comparative Medicine, Columbia University, New York City, NY, ³Department of Pathology and Cell Biology, Columbia University, New York City, NY
*Purpose: Regulatory Tcell (Treg) therapy is a promising tool for tolerance induction in solid organ transplantation. Despite encouraging results in humans and monkeys, questions about…
2020 American Transplant Congress
Proposed New Kidney Allocation Policy: Moving to Concentric Circles as the First Unit of Allocation
A. Israni¹, S. Gustafson¹, A. Wey¹, B. Thompson¹, V. Casingal², M. Pavlakis³, S. Castro⁴, A. Wilk⁴, B. Kasiske¹, J. Snyder¹
¹SRTR, Minneapolis, MN, ²Carolinas Healthcare, Charlotte, NC, ³Beth Israel Deaconess, Boston, MA, ⁴UNOS, Richmond, VA
*Purpose: The Organ Procurement and Transplantation Network (OPTN) proposed a new national deceased donor kidney allocation policy that removes donor service area and OPTN region…
2020 American Transplant Congress
Living Donor Liver Transplantation Demonstrated Superiority to Deceased Donor Transplantation after Adult-To-Adult Liver Transplantation in Cumulative Single-Center Retrospective Cohort Study of 19 Years
T. Goto, T. Reichman, G. Sapisochin, I. McGilvray, M. Selzner, A. Ghanekar, M. Cattral, N. Selzner
Multi-Organ Transplant Program, Toronto General Hospital, Institute of Medical Science, University of Toronto, Toronto, ON, Canada
*Purpose: Living donor liver transplantation (LDLT) is an alternative way to deceased donor liver transplantation (DDLT). LDLT and DDLT showed similar short-term outcomes of recipient…
2020 American Transplant Congress
Cytomegalovirus Infection and Outcomes in Pancreas Transplant Recipients in the Prophylaxis Era
M. Jorgenson¹, N. Marka², G. Leverson², J. Smith², J. Odorico²
¹UW Health, Madison, WI, ²UWMF, Madison, WI
*Purpose: Evaluate epidemiology and outcomes of cytomegalovirus infection (CMV) in pancreas transplant recipients (PTR) in the current era of valganciclovir (VGC) prophylaxis (PPX)*Methods: Adult PTRs…
2020 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Future Proteinuria
S. Jordan¹, P. Sood², J. Bromberg³, D. Brennan⁴
¹Cedars-Sinai, Los Angeles, CA, ²University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Maryland, Baltimore, MD, ⁴The Johns Hopkins Hospital, Baltimore, MD
*Purpose: Most allografts with proteinuria >1500 mg/dL have new glomerular pathology. In contrast, lower levels of proteinuria are generally associated with non-glomerular, nonspecific histologic changes.…
2020 American Transplant Congress
Increased Post-Operative Ventilation Time in Lung Transplant Recipients with Left Ventricular Diastolic Dysfunction
E. Klipsch¹, R. Rachwan², I. KutKut³, D. Roe², C. Hage², T. Hathaway¹, R. S. Mangus²
¹Indiana University School of Medicine, Indianapolis, IN, ²IU Health, Indianapolis, IN, ³New York Presbyterian Brooklyn Methodist Hospital, New York, NY
*Purpose: Left ventricular diastolic dysfunction has been shown to be associated with increased morbidity in bilateral lung transplant recipients with pulmonary artery hypertension. It has…
2020 American Transplant Congress
Antibody-Suppressor CD8⁺ T Cells Ameliorate Antibody-Mediated Rejection Following Kidney Transplant in Mice
J. M. Zimmerer¹, J. L. Han¹, Q. Zeng², B. A. Ringwald¹, C. Cassol¹, R. Warren¹, M. Abdel-Rasoul¹, C. K. Breuer², G. L. Bumgardner¹
¹Ohio State University, Columbus, OH, ²Nationwide Children's Hospital, Columbus, OH
*Purpose: We previously reported the novel alloantibody suppressor activity of alloprimed CXCR5+IFN-γ+CD8+ T cells following hepatocellular transplant in mice. We utilized a murine kidney transplant…
2020 American Transplant Congress
Thymoglobulin (ATG) Induction vs. Campath vs. Simulect in DCD Kidneys in UK; Induction Regimes Play a Role after All
A. Asderakis¹, T. Sabbah¹, J. Watkins², L. Szabó¹, D. Elker¹, A. M. Ilham¹, E. Ablorsu¹, M. Stephens¹, U. Khalid¹, R. Chavez¹
¹Cardiff Transplant Unit,, University Hospital of Wales, Cardiff, United Kingdom, ²Infection and Immunity, Cardiff University, Cardiff, United Kingdom
*Purpose: Controlled DCD kidneys have increased dramatically in UK. They suffer from a higher rate of DGF and, often in UK, come from older donors…
2020 American Transplant Congress
Characteristics of Anonymous Living Donors and Their Recipients. Appropriate Use of a Rare and Valuable Gift
A. Sharfuddin, M. Panezai, M. Yaqub, D. Mishler, O. Adebiyi, T. Taber
Indiana University School of Medicine, Indianapolis, IN
*Purpose: Anonymous Living Donors are a special select set of donors. As there continues to be advances in Paired Donation, we review the trends and…
2020 American Transplant Congress
Adult Living Donor Liver Transplantation Results in Superior Patient and Graft Survival When Compared to Deceased Donor Liver Transplantation: A Systematic Review and Meta-Analysis
A. Barbetta¹, M. Aljehani², M. KIM¹, C. Tien³, A. Ahearn¹, H. Schilperoort², L. Sher¹, J. Emamaullee¹
¹Surgery, abdominal transplat, University of Southern California, Los Angeles, CA, ²University of Southern California, Los Angeles, CA, ³Surgery, abdominal transplat, Keck Medical School, University of Southern California, Los Angeles, CA
*Purpose: Center-specific or national registry studies have shown that living donor liver transplantation (LDLT) decreases waitlist mortality, reduces waiting time, and may offer superior patient…