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Articles tagged "Sirolimus (SLR)"

  • 2015 American Transplant Congress

    Induction of a Costimulation-Susceptible Repertoire: A Case for Depletional Prior to Belatacept

    H. Xu,1 K. Samy,1 A. Guasch,2 S. Mead,2 A. Kirk.1

    1Surgery, Duke University, Durham, NC; 2Transplant Center, Emory University, Atlanta, GA.

    Belatacept offers highly specific costimulation blockade to prevent recipient alloimmune responses with reduced toxicity. However, when applied with nondepletional induction therapy belatacept-based regimens have higher…
  • 2015 American Transplant Congress

    Conditioning of Mesenchymal Stromal Cells With mTOR Inhibitor Enhances Regenerative Properties of Secretome and Attenuates Vascular Calcification

    B. Hegner,1 C. Kurth,1 T. Schaub,1 C. Lange,2 D. Dragun.1

    1Clinic for Nephrology and Intensive Care Medicine, Charité University Hospital, Berlin, Germany; 2Department of Cell and Gene Therapy, University Medical Center Eppendorf, Hamburg, Germany.

    Similar to patients with chronic kidney disease, recipients of kidney transplants are a high-risk population for cardiovascular events due to arterial media calcification in particular…
  • 2015 American Transplant Congress

    Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction

    B. Duhart,1 W. Ally,2 V. Rao,3 A. Krauss,4 J. Eason,3 J. Vanatta.3

    1University of Tennessee College of Pharmacy, Memphis, TN; 2Pharmacy, University of Virginia Medical Center, Charlottesville, VA; 3Surgery, Methodist University Hospital Transplant Institute/University of Tennessee Health Science Center, Memphis, TN; 4Pharmacy, Methodist University Hospital, Memphis, TN.

    Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…
  • 2015 American Transplant Congress

    Sirolimus Based Maintenance Immunosuppression in Pancreas Transplant Recipients

    A. Rajab, R. Pelletier, E. Elkhammas, G. Bumgardner, A. El-Hinnawi, M. Henry.

    Surgery, The Ohio State University, Columbus, OH.

    The present study evaluated the outcome of a Sirolimus based maintenance immunosuppressive protocol in pancreas transplant recipients. Between August 2003 and December 2013, a total…
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