2021 American Transplant Congress
Quantifying Hidden Sensitization: HLA-reactive Memory B Cells in the Spleens of Sensitized Women
*Purpose: Measurement of circulating anti-HLA antibody (anti-HLA-Ab) in transplant candidates and recipients is required for successful organ transplantation. However, serum Ab measurement alone likely underestimates…2021 American Transplant Congress
Anti-HLA-DP Antibodies Positive – A Retrospective Review of Outcomes in Renal Transplantation- Single Centre Experience
*Purpose: Data on the role of HLA-DP antibodies on graft outcome is not precise. Studies suggested that the presence of donor-directed HLA-DP antibodies correlate with…2021 American Transplant Congress
Anti-pig IgE and IgA Antibodies in Sera of (i) Naïve Primates and (ii) Non-human Primates Sensitized to Pig Xenografts
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Anti-pig IgM and IgG antibodies in primates play an important role in xenograft rejection. The possible roles of anti-pig IgE and IgA have not…2021 American Transplant Congress
The Incremental Cost of Transplanting Patients with 100% cPRA Under the Kidney Allocation System: A Single Center Analysis
Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Our group has described excellent three year patient and graft survival in patients with 100% cPRA undergoing kidney transplantation under the Kidney Allocation System…2021 American Transplant Congress
Outcomes in Highly Sensitized Kidney Transplant Recipients Receiving DCD Organs
*Purpose: Highly sensitized (HS) patients experience longer wait times for kidney transplantation despite prioritization by the Kidney Allocation System. Kidney transplants performed from donors defined…2021 American Transplant Congress
Outcomes of Kidney Transplantation in HIV Positive Highly Sensitized Recipients
Temple University School of Medicine, Philadelphia, PA
*Purpose: Since the introduction of highly active antiretroviral therapy, HIV+ individuals are living longer, which has led to higher rates of end stage renal disease…2021 American Transplant Congress
Factors Affecting Sensitization Following Kidney Allograft Failure
*Purpose: Kidney transplant (KT) recipients with failed allografts constitute nearly 12% of the current waitlist in the US. Sensitization as a result of graft failure…2021 American Transplant Congress
The Effect of Daratumumab (Dara, Humanized Anti-CD38 Monoclonal Antibody) on Immune Cells In Vitro and in a HLA-Sensitized Kidney Transplant Patient (HS KTx Pt) Desensitized (DES) with Dara
*Purpose: Antibody-Mediated Rejection (ABMR), primarily mediated by B cells, plasma cells (PC) and antibodies (Ab), is an obstacle for successful transplantation in HS KTx Pts.…2021 American Transplant Congress
Very Long-Term Patient and Kidney Allograft Outcomes in Kidney Transplant Recipients More Than 20 Years After Transplantation:
University Hospital Zurich, Zürich, Switzerland
*Purpose: Despite rapid medical advancements in the field of transplantation over the last decades, long-term kidney allograft survival only slowly improves. Especially little is known…2021 American Transplant Congress
Among Patients with Pre-Transplant Donor-Specific Antibodies, the Disappearance of the Donor-Specific Antibodies at 3 Months is Not Associated with Less Rejection
University of Wisconsin, Madison, WI
*Purpose: The number of sensitized kidney transplant recipients (KTRs) are increasing on the waiting list. Some KTRs receive an organ in the presence of pretransplant…
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