ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Sensitization"

  • 2015 American Transplant Congress

    Costimulation Blockade and Bortezomib to Desensitize Rhesus Macaque and Prolong Renal Allograft Survival

    J. Kwun, C. Burghuber, E. Page, A. Gibby, N. Iwakoshi, S. Knechtle.

    Surgery, Emory Transplant Center, Atlanta, GA.

    [Background] Preformed donor specific antibody (DSA) due to prior sensitization affects a significant population of transplant patients, portending a poorer prognosis in short- and long-term…
  • 2015 American Transplant Congress

    Desensitization Before Living Donor Kidney Transplantation in Highly Sensitized Patients

    E. De Sousa,1 I. Revuelta,1 M. Blasco,1 F. Diekmann,1 J. Cid,2 M. Lozano,2 A. Sánchez-Escuredo,1 J. Martorell,3 E. Palou,3 J. Campistol,1 F. Oppenheimer.1

    1Nephrology, Hospital Clinic Barcelona, Barcelona, Spain; 2Hemotherapy and Hemostasis, Hospital Clinic Barcelona, Barcelona, Spain; 3Immunology, Hospital Clinic Barcelona, Barcelona, Spain.

    Renal transplantation in highly sensitized patients represents a major clinical challenge leading to long periods in the waiting list. When a living donor is available,…
  • 2015 American Transplant Congress

    A Prospective Pilot Study Evaluating the Safety and Efficacy of Everolimus for the Prevention of CMV and BK Viral Infection (BKV) in Broadly Sensitized Kidney Transplant Recipients Following Desensitization With IVIG and Rituximab: Interim Analysis

    J. Kahwaji,1 S. Louie,1 A. Vo,1 J. Choi,1 M. Toyoda,2 S. Ge,2 P. Wongsaroj,1 A. Peng,1 R. Villicana,1 S. Jordan.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Transplant Immunology Lab, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: Everolimus, a second generation mTOR inhibitor, may prevent CMV and BKV infection after kidney transplantation. Broadly sensitized patients are at greater risk of viral…
  • 2015 American Transplant Congress

    Rituximab With Intravenous Immune Globulin in Sensitized Patients Awaiting Heart Transplant: Does It Work?

    J. Patel, N. Reinsmoen, M. Kittleson, A. Velleca, D. Dilibero, F. Liou, D. Chang, A. Hage, L. Czer, F. Esmailian, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Highly sensitized heart transplant (HTx) recipients with donor specific antibodies (DSA) are at increased risk of rejection and death. Rituximab with Intravenous Immune Globulin…
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