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Articles tagged "Sensitization"

  • 2015 American Transplant Congress

    Sensitization Level at Retransplant Among Non-Sensitized Pediatric Recipients of First Deceased Donor Kidney Transplants Not Affected by DR Mismatch Level

    W. Cherikh,1 A. Wilk,1 H. McGehee,1 E. Brewer.2

    1United Network for Organ Sharing, Richmond, VA; 2Baylor Coll Med & Texas Children's Hosp, Houston, TX.

    Background. Most pediatric (ped) kidney (KI) recipients (recips) received 1- or 2-DR HLA mistmached (MM) deceased donor (DD) kidneys. The degree of HLA MM between…
  • 2015 American Transplant Congress

    T-Cell Depletion Versus Interleukin-2 Antagonists in a Kidney Transplant Model of Sensitized Rhesus Macaques

    C. Burghuber,1,2 J. Kwun,1 E. Page,1 F. Leopardi,3 A. Gibby,1 A. Farris,1 N. Iwakoshi,1 S. Knechtle.1

    1Emory University, Atlanta, GA; 2Medical University Vienna, Vienna, Austria; 3Duke University, Durham, NC.

    [Background] Sensitized patients comprise up to a third of the kidney waiting list. Preformed and newly formed alloantibodies post transplantation (TX) deteriorate graft survival, recall…
  • 2015 American Transplant Congress

    Pancreas After Failed Islet Transplantation; a Successful Strategy to Maintain Insulin Independence

    J. Gardner,1 G. Roll,1 S. Wisel,1 J. Harbell,1 B. Hynson,1 D. Kaufman,2 A. Posselt,1 P. Stock.1

    1Department of Surgery, University of California, San Francisco, San Francisco, CA; 2Department of Surgery, University of Wisconsin, Madison, WI.

    Introduction: As islet transplantation (tx) remains an experimental and uninsured procedure, there are no established protocols to achieve insulin independence following failure of the islet…
  • 2015 American Transplant Congress

    Distinct Subtypes of Rejection in a Novel Non Human Primate Model of Sensitization

    C. Burghuber,1,2 J. Kwun,1,3 F. Leopardi,3 A. Gibby,1 A. Farris,1 N. Iwakoshi,1 S. Knechtle.1,3

    1Emory University, Atlanta, GA; 2Medical University Vienna, Vienna, Austria; 3Duke University, Durham, NC.

    [Background] Preformed and newly formed alloantibody post transplantation (TX) can significantly deteriorate graft survival. Patterns of humoral rejection in sensitized patients varies significantly due to…
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