2017 American Transplant Congress
De Novo Donor-Specific Antibodies After Allograft Nephrectomy.
Introduction: although the development of donor-specific antibodies (DSAs) is a known event after allograft nephrectomy (Nx), there are few studies describing the tempo, class and…2017 American Transplant Congress
Prevention of Donor Specific Antibody Production After Skin Allografting by Mobilization of Endogenous Stem Cells Using a Combination of AMD3100 and Low-Dose FK506 in Rats.
Background: We have developed a stem cell mobilizing strategy that enables long-term liver and kidney allograft survival without sustained immunosuppression in small and large animals…2017 American Transplant Congress
Significant Allosensitisation Despite Early, within 24 Hour, Graft Nephrectomy.
Introduction: Although it is well known that allograft nephrectomy (Nx) is followed by the development of donor-specific antibodies (DSAs) even after a short transplant period,…2017 American Transplant Congress
HLA Alloimmunization According to the Different Immunization Events and Consequences on Access to Kidney Transplantation.
Patients awaiting solid organ transplantation may develop anti-HLA antibodies after sensitization events such as transfusions, pregnancies or previous transplantations. The aim of our work was…2017 American Transplant Congress
Shared Epitopes Contribute to Accumulation of Highly Sensitized Patients in Kidney Paired Donation Program.
University of Toledo, Toledo, OH
Introduction: Kidney Paired Donation (KPD) programs suffer from the accumulation of highly sensitized patients. We evaluated the sensitization patterns in our KPD program-by comparison of…2017 American Transplant Congress
Exploring Differential Antibody Response to Bortezomib in Heart Transplantation.
Northwestern University, Chicago, IL
Twelve heart transplant candidates (2013-2016) received Bortezomib (BTZ) for desensitization. Differential antibody (Ab) response was observed. BTZ cycles consisted of 4 injections of 1.3 mg/m2;…2017 American Transplant Congress
Even with National Sharing, the Prospects of a 100% Sensitized Patient Receiving a Transplant Vary Dramatically Depending on the Precise CPRA Value.
1UNOS, Richmond, VA; 2Stanford Univ, Palo Alto, CA; 3Emory Univ Hosp, Atlanta, GA
Background: In the Kidney Allocation System (KAS), CPRA of 99% & 100% candidates receive regional and national priority. This broader sharing, along with adoption of…2017 American Transplant Congress
Post-Transplant Sensitization: Does it Make a Difference in the Development of First-Year Intimal Thickening?
Cedars-Sinai Heart Institute, Los Angeles
Background: The development of donor specific antibody (DSA) after heart transplantation has been reported to be associated with the development of cardiac allograft vasculopathy (CAV).…2017 American Transplant Congress
Waitlist Desensitization and the Rate of Deceased Donor Kidney Transplantation After Implementation of the Kidney Allocation System.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Background:At Cedars Sinai Medical Center (CSMC), candidates with calculated panel reactive antibodies (cPRA) ≥30% (based on unacceptable antigens with MFI≥15,000) are desensitized while awaiting transplant.…2017 American Transplant Congress
CTLA4-Ig in Combination with FTY720 Reduces the Frequency of Memory Alloreactive T Cells and Promotes Heart Allograft Survival in Sensitized Recipients.
Despite recent evidence of improved graft outcomes and safety, high incidence of early acute cellular rejection with belatacept has limited its use in clinical transplantation.…
- « Previous Page
- 1
- …
- 11
- 12
- 13
- 14
- 15
- …
- 19
- Next Page »