2018 American Transplant Congress
Pre-Transplant Memory Patients Even without Detected Antibody Are at Rejection Risk in the First-Year after Heart Transplantation
Cedars Sinai Medical Center, Los Angeles.
Purpose: Patients (pts) with prior transplants, blood transfusions, and pregnancies awaiting heart transplantation (HTx) have potential to develop circulating anti-HLA antibodies (HLA Abs). Pts at…2018 American Transplant Congress
MCS and Desensitization
Cedars Sinai Medical Center, Los Angeles.
Purpose: Sensitization prior to heart transplantation (HTx) has been associated with increased mortality and rates of rejection as well as an increased incidence of cardiac…2018 American Transplant Congress
Evanescent Antibodies: A Report on the Natural History of Anti-Blood Group A2 Antibodies and Their Rapid Resolution in Patients Awaiting A2 to B Transplantation
Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.
Introduction: Despite the benefits of A2 to B transplants, centers have been reluctant to adopt such a program due to unanswered questions including whether elevation…2018 American Transplant Congress
Clinical Outcomes of Conversion from Calcineurin Inhibitor to Belatacept-Based Immunosuppression in Highly Sensitized Kidney Transplant Recipients
Cedars Sinai Medical Center, Los Angeles.
Introduction:Efficacy of belatacept when converted from calcineurin inhibitors (CNI) in high immunologic risk patients has not been established. We examined the impact of HLA-sensitization on…2018 American Transplant Congress
Many Highly Sensitized Candidates Still Waiting for Transplant Despite the Kidney Allocation System Change: Making the Case for Incompatible Transplantation
Introduction: The rate of kidney transplantation in highly sensitized individuals has increased since the kidney allocation system (KAS) change, but it remains unclear who has…2018 American Transplant Congress
Elevated Skin Specific Non-HLA Antibodies Correlate with Acute Rejection Episodes in Clinical VCA
Introduction: Vascularized composite allotransplantation (VCA) is unique by presence of the skin in the allografts. Due to the high immunogenicity of skin and the presence…2018 American Transplant Congress
Immune Profiling in Highly Sensitized Kidney Transplant Recipients
Surgery, McGill University, Montreal, Canada.
Introduction: Highly sensitized patients (HSP) express foreign HLA antibodies and have poor graft survival due to higher incidences of graft rejection as compared to non-sensitized…2018 American Transplant Congress
Memory T Cell Dysfunction after Pregnancy Alloimmunization Prolongs Transplant Survival
Background Pregnancy alloimmunization can preclude donor compatibility and may diminish transplant lifespan. While these consequences may be attributed to immunologic memory responses that endanger an…2018 American Transplant Congress
Two Similar Risk Models Identify Different Patients for Graft Loss: Implications for Clinical Trials in DSA+ Kidney Transplant Recipients
William J von Liebig Transplant Center, Mayo Clinic, Rochester.
Introduction. Kidney Transplant Recipients (KTx) with donor-specific alloantibody (DSA) at transplantation have increased death-censored graft failure (DCGF) due to chronic antibody mediated rejection (cABMR), but…2018 American Transplant Congress
Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells
Introduction: Clinical data suggest allogeneic pregnancy is a sensitizing event; yet, recent data from mouse models indicates it induces fetal-specific regulatory T cell (Treg) expansion…
- « Previous Page
- 1
- …
- 8
- 9
- 10
- 11
- 12
- …
- 19
- Next Page »