Articles tagged "Screening"

2020 American Transplant Congress
Identification of Novel Gene Targets Inducing Resistance in Liver Ischemia Reperfusion Injury by CRISPR Screening
C. Kuscu, A. R. Wolen, C. Kuscu, C. Watkins, A. Bajwa, J. D. Eason, D. Maluf, V. Mas
Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN
*Purpose: Liver transplantation (LT) is the best treatment option for patients with end-stage liver disease (ESLD). However, the gap between available donors and recipients in…
2020 American Transplant Congress
Self-Reported Marijuana Use and its Effects on Overall Approval in Potential Living Kidney Donors
C. Delvalle, R. Fatica, J. Augustine
Kidney & Pancreas Transplant, Cleveland Clinic, Cleveland, OH
*Purpose: Past and present substance use is an important part of the psychosocial evaluation of potential living kidney donors. Increasing state legalizations and social acceptance…
2020 American Transplant Congress
Physician Survey on Using APOL1 Genetic Testing in Live Kidney Donor Selection
M. Doshi¹, E. Gordon², B. Freedman³, C. Thomas⁴, C. Glover⁵, J. Locke⁶
¹Medicine, University of Michigan, Ann Arbor, MI, ²Surgery, Northwestern University, Chicago, IL, ³Medicine, Wake Forest, Winston-Salem, NC, ⁴Medicine, University of Iowa, Iowa City, IA, ⁵N/A, Miami, FL, ⁶Surgery, University of Alabama, Birmingham, AL
*Purpose: Live kidney donors of recent African ancestry are at an increased risk of developing end stage kidney disease than matched healthy non-donors. A recent…
2020 American Transplant Congress
Donor-Specific Antibody Test as a Screening Tool for Stable Long-Term Kidney Transplant Recipients
M. Mohamed¹, L. Hidalgo², S. Parajuli¹, N. Garg¹, F. Aziz¹, K. Swanson¹, E. Jochaim¹, D. Mandelbrot¹, A. Djamali¹, B. Astor¹
¹Department of Nephrology, Madison, WI, ²Department of Surgery, Madison, WI
*Purpose: Donor-specific antibody (DSA) is an established biomarker predicting antibody mediated rejection (AMR), but at substantial cost. The utility of DSA test as a screening…
2020 American Transplant Congress
A Single-Center Characterization of the Living Liver Donor Evaluation Process
L. R. Herbst, A. D. Love, M. Krach, Y. Yu, L. Kurman, A. Gurakar, M. Hammami, A. M. Cameron, J. Garonzik Wang
Department of Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: We have previously characterized the living kidney donor evaluation and found that African American (AA) donors were less likely to progress through the process…
2020 American Transplant Congress
Reactivation of BK Polyomavirus after Kidney Transplantation: A Multi-Center Collaboration Examining the Impact of Adherence to a Screening Protocol on Clinical Outcomes
R. Rogers¹, F. Cheema², M. Chobanian³, Z. Ebcioglu², H. Gilligan⁴, R. Gohh¹, N. Goyal⁵, M. Pavlakis⁶, N. Rodig⁷, A. Rossi⁸, J. Singh², C. S. Tan⁶
¹Warren Alpert Medical School of Brown University, Providence, RI, ²Hartford Hospital, Hartford, CT, ³Geisel School of Medicine at Dartmouth, Hanover, NH, ⁴Massachusetts General Hospital, Boston, MA, ⁵Tufts University School of Medicine, Boston, MA, ⁶Beth Israel Deaconess Medical Center, Boston, MA, ⁷Boston Children's Hospital, Boston, MA, ⁸Maine Medical Center, Portland, ME
*Purpose: Reactivation of BK polyomavirus (BK) after kidney transplantation (KT) is common and can lead to adverse clinical outcomes such as allograft nephropathy (BKAN). In…
2020 American Transplant Congress
The Impact of DSA Screening in Stable Kidney Transplant Recipients in the 1st Year Post-Transplant
A. Sharma¹, D. Jorgensen², R. Mehta¹, P. Sood¹, C. Wu¹, C. M. Puttarajappa¹, A. Tevar¹, S. Hariharan¹
¹Thomas E. Starzl Transplant Institute, Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Thomas E. Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The importance of Donor Specific Antibody (DSA) as a screening tool within the 1st year post kidney transplant in stable patients remains unclear. We…
2020 American Transplant Congress
Cognitive Impairment is Highly Prevalent in Lung Transplant Candidates
A. O'Boye, K. Leitner, M. Kelly, J. Wright, L. Pesce, M. Sala, R. Tomic
Northwestern Medicine, Chicago, IL
*Purpose: Lung transplantation is a lifesaving therapy in patients with advanced lung disease. Lung transplant recipients must have the ability to manage complex medical regimens…
2020 American Transplant Congress
Utility of Bimonthly Viral Monitoring for Late-Onset Cytomegalovirus Infections in Kidney Transplant Recipients
I. Melgarejo¹, D. Jorgensen², S. Hariharan², C. Puttarajappa²
¹Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, ²Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
*Purpose: Kidney transplant recipients with high-risk cytomegalovirus (CMV) serostatus are at risk for late onset CMV after cessation of antiviral prophylaxis.1-2 Evidence for post-prophylactic viral…
2020 American Transplant Congress
Pattern of Renal Allograft Injury in Recipients with Normal Donor-Derived Cell-Free DNA
W. Xie, N. Goussous, A. Haririan, M. Weir, J. Bromberg
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a novel non-invasive test currently used as a biomarker for identification of transplant rejection or injury. Here, we sought…

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