Articles tagged "Risk factors"

2016 American Transplant Congress
Three-Year Graft Loss Risk in Kidney Transplants: Dynamic Patient Level Data Improve Predictive Efficacy.
T. Srinivas, J. Zhang, Z. Su, D. Taber, J. Marsden, K. Reilly, D. Northrup, J. Long, L. Lenert, W. Moran, P. Mauldin.
MUSC, Charleston, SC.
Background: Predictive models in kidney transplantation using national data (UNOS, SRTR) lack longitudinal patient level data, limiting accuracy. Adding patient level data capturing dynamic clinical…
2016 American Transplant Congress
Obesity Is Associated with Increased Risk of ESRD Among Living Kidney Donors.
J. Locke,¹ C. Lewis,¹ R. Reed,¹ V. Kumar,¹ D. Sawinski,² A. Massie,³ P. MacLennan,¹ R. Mannon,¹ R. Gaston,¹ D. Segev.³
¹School of Medicine, University of Alabama at Birmingham, Birmingham, AL; ²School of Medicine, University of Pennsylvania, Philadelphia, PA; ³School of Medicine, Johns Hopkins University, Baltimore, MD.
Background: Living kidney donor (LKD) demographics have changed, and transplant centers have relaxed selection criteria to include LKDs who are obese. Prior studies of LKDs…
2016 American Transplant Congress
VDJ Immune Repertoire Sequencing Predicts Patients at Risk of Alloimmune Injury.
M. Sirota,¹ T. Sigdel,¹ S. Boyd,² A. Fire,² M. Sarwal.¹
¹Surgery and Bioinformatics, UCSF, San Francisco, CA; ²Genetics, Stanford University, Palo Alto, CA.
Background: The complex repertoire of immune receptors generated by B cells enables allo-recognition in the context of transplantation across HLA barriers, and is a major…
2016 American Transplant Congress
Review of Organ Utilization from Increased Infectious Risk Donors.
A. L'Huillier,¹ A. Humar,² C. Payne,³ D. Kumar.²
¹Division of Infectious Diseases, Hospital for Sick Children and University of Toronto, Toronto, Canada; ²Transplant Infectious Diseases and Multi-Organ Transplant Program, University Health Network, Toronto, Canada; ³Trillium Gift of Life Network, Toronto, Canada.
IntroductionDonors with an increased risk of transmitting HIV, HBV or HCV (IRDs) are a potential source of organs. There is a lack of data on…
2016 American Transplant Congress
Anti-Thymocyte Globulin Induction Does Not Increase the Risk of Thrombotic Events in Kidney Transplantation: A Matched Case-Control Study.
J. Iuppa,¹ M. Dokus,² E. Venniro,³ A. Patel,² A. Danzig,⁴ J. Hahn,¹ R. Kashyap,² M. Orloff,² J. Taylor.³
¹Department of Pharmacy, University of Rochester, Rochester, NY; ²Department of Surgery, Division of Transplantation and Hepatobiliary Surgery, University of Rochester, Rochester, NY; ³Department of Medicine, Division of Nephrology, University of Rochester, Rochester, NY; ⁴School of Medicine and Dentistry, University of Rochester, Rochester, NY.
Background: Anti-thymocyte globulin (ATG) is the most commonly used induction agent in kidney transplantation (KTx). To date, case reports and in vitro analyses have suggested…
2016 American Transplant Congress
Epidemiology of Surgical Site Infections After Liver Transplantation: 4 Year Prospective Study.
Y. Natori, R. Kassar, A. Iaboni, S. Hosseini-Moghaddam, D. Vu, S. Husain, E. Renner, C. Rotstein.
Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada.
IntroductionDeceased and living donor liver transplantation (LT) is a lifesaving procedure for individuals with liver failure. However, despite the use of perioperative antibiotic prophylaxis at…
2016 American Transplant Congress
Pre-Transplant Cardiovascular Risk Factors Affect Kidney Allograft Survival: A Multi-Center Study in Korea.
J. An,^1,2 S. Ahn,³ E. Bae,² E. Kang,² H.-L. Kim,⁴ Y.-J. Kim,⁵ Y. Oh,^1,2 C. Lim,^1,2 Y. Kim,² Y. Kim,⁶ J. Lee.^1,2
¹Division of Nephrology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ²Division of Nephrology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, Gangwon-do, Korea; ⁴Division of Cardiology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ⁵Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ⁶Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Background - Pre- or post-transplant cardiovascular (CV) risk factors affect the development of CV events even after successful kidney transplantation (KT). However, the impact of…
2016 American Transplant Congress
Clinical Factors That Determine the Appropriateness of Early Steroid Withdrawal.
S. Bae, A. Massie, S. DiBrito, X. Luo, L. Kucirka, D. Segev.
Johns Hopkins, Baltimore, MD.
Early steroid withdrawal (ESW) has been a popular option for recipients with low-immunological risk. However, no quantitative tools are available to assess the risk, i.e.…
2016 American Transplant Congress
Early Changes to Kidney Distribution Under the New Kidney Allocation System.
A. Massie,¹ X. Luo,¹ B. Lonze,¹ N. Desai,¹ A. Bingaman,² M. Cooper,³ D. Segev.¹
¹JHU, Baltimore; ²Methodist, San Antonio; ³Georgetown, Washington.
In December 2014, the Kidney Allocation System (KAS), a major change to kidney allocation, was implemented, granting increased priority to younger candidates and candidates with…
2016 American Transplant Congress
Use of the Psychosocial Assessment Tool to Identify Risk in Families of Pediatric Liver Transplant Recipients.
E. Fredericks, T. Smith, J. Sevecke, S. Eder, C. Limke, C. Shneider, M. Lopez.
Pediatrics, University of Michigan, Ann Arbor, MI.
Purpose: Although families of pediatric liver transplant recipients have documented psychosocial needs, the systematic identification of needs and delivery of evidence-based care remain challenging. This…