Articles tagged "Risk factors"

2019 American Transplant Congress
Keeping Patients Lifetime Perspective in Focus: Modest Rates and Wide Variation in Preemptive Re-Listing for Kidney Transplantation in the US
J. Schold, J. Augustine, A. Huml, J. O'Toole, J. Sedor, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: Success of transplantation is not limited to initial receipt of a donor organ. Many patients experience graft loss within their lifetime and the benefits…
2019 American Transplant Congress
A Prognostic Biomarker to Estimate the Likelihood of Developing De Novo Donor Specific Antibody in Kidney Transplant Recipients
S. Kawakita¹, L. M. Rebellato², K. P. Briley², A. Q. Maldonado³, C. E. Haisch², P. Bolin², S. A. Kendrick⁴, H. Jones⁴, K. McLawhorn⁴, D. Leeser², V. Jucaud¹, V. Burnett¹, M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²East Carolina University, Greenville, NC, ³Vidant Medical Center, Greenville, NC, ⁴Eastern Nephrology Associates, Greenville, NC
*Purpose: Evaluation of human leukocyte antigen (HLA) mismatch at antibody epitope level rather than antigen level may explain better the impact of HLA mismatch on…
2019 American Transplant Congress
Delayed Graft Function as a Survival Prognostic Factor in Elderly Recipients of Kidney Transplantation
G. J. Piñeiro, E. Guillen, P. Ventura, J. V. Torregrosa, R. Gelpi, I. Revuelta, F. Cofan, E. De Sousa, D. Cucchiari, J. Ugalde, F. Oppenheimer, F. Diekmann, N. Esforzado
Nephrology and Kidney Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain
*Purpose: Kidney transplantation (KT) provides advantages in terms of survival compared with dialysis. However, in elderly recipients, despite a better long-term survival, a high mortality…
2019 American Transplant Congress
Speckle Echo Pre and Post Kidney Transplant: A Pilot Study
M. Olivares-Perez¹, Y. Gao¹, A. Webber¹, F. Ghahghaie¹, M. Lassen², A. Qasim¹, M. Park¹
¹University California, San Francisco, San Francisco, CA, ²University of Copenhagen, Copenhagen, Denmark
*Purpose: Relative to dialysis, cardiovascular (CV) mortality improves with transplantation. Nevertheless, CV disease (CVD) is the leading cause of death for kidney transplant recipients (KTR),…
2019 American Transplant Congress
CXCL12-CXCR4-Mediated Chemotaxis is a Potential Mechanism for Monocyte Recruitment in Ischemia-Reperfusion Injury in Orthotopic Liver Transplant Patients
A. Q. Terry¹, R. A. Sosa¹, B. V. Naini¹, V. Groysberg¹, F. M. Kaldas², R. W. Busuttil², D. Gjertson¹, J. Kupiec-Weglinski², E. F. Reed¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, ²Surgery, University of California, Los Angeles, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which lowers allograft survival in orthotopic liver transplant (OLT) patients. Damage-associated molecular patterns, such as high-mobility group box…
2019 American Transplant Congress
CMV Risk Status Remains a Relevant Risk Factor for Long-Term Outcomes
G. Karadkhele, W. Zhang, C. P. Larsen
Emory University, Atlanta, GA
*Purpose: Intensification of immunosuppression using T cell depleting induction has reduced rates of acute cellular rejection after kidney transplantation. Belatacept, a first in class T…
2019 American Transplant Congress
Quantifying Donor Effects on Transplant Outcomes Using Kidney Pairs from Deceased Donors
K. F. Kerr¹, E. R. Morenz¹, H. Thiessen Philbrook², S. G. Coca³, F. P. Wilson⁴, P. P. Reese⁵, C. R. Parikh²
¹University of Washington, Seattle, WA, ²Johns Hopkins University, Baltimore, MD, ³Icahn School of Medicine at Mount Sinai, New York, NY, ⁴Yale University, New Haven, CT, ⁵University of Pennsylvania, Philadelphia, PA
*Purpose: In kidney transplantation, the relative contribution of donor versus other factors on clinical outcomes is unknown.*Methods: For paired donations from deceased donors resulting in…
2019 American Transplant Congress
Significance of Histopathologic Features for Predicting Progression in Patients with Transplant Glomerulopathy
X. Li, J. Chen, D. Cheng, R. Wang, W. Wang, M. Zhang, F. Xu, J. Wen, Z. Tang
National Clinical Research Center of Kidney Diseases, Nanjing, China
*Purpose: Transplant glomerulopathy (TG) represents a major cause of long-term allograft failure and is the leading cause of overall post-transplant proteinuria. We aimed to determine…
2019 American Transplant Congress
Induction with Thymoglobulin in DCD Kidneys. Dose Effect and Predictors of Outcome
A. Asderakis, T. Sabah, A. Jones, E. Ablorsu, L. Szabó, R. Chavez
Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom
*Purpose: Thymoglobulin (ATG) is used only in few UK centres as induction. We have previously shown good results with ATG for pancreas transplants. The aim…
2019 American Transplant Congress
Alterations in Brain Metabolites before and after Kidney Transplant
A. Gupta¹, P. Lee², R. Lepping³, A. Jurgensen¹, J. Klein¹, P. Adany⁴, D. Cibrik¹, J. Burns⁵, W. Brooks³, I. Choi⁶
¹Division of Nephrology, The Kidney Institute, University of Kansas Medical Center, Kansas City, KS, ²Hoglund Brain Imaging Center, Department of Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, ³Hoglund Brain Imaging Center, Alzheimer’s Disease Center,, University of Kansas Medical Center, Kansas City, KS, ⁴Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, ⁵Alzheimer’s Disease Center, Department of Neurology, University of Kansas Medical Center, Kansas City, KS, ⁶Hoglund Brain Imaging Center, Department of Neurology, University of Kansas Medical Center, Kansas City, KS
*Purpose: End stage renal disease (ESRD) is associated with accumulation of uremic metabolites and poor cognitive performance. Alterations in brain metabolites are associated with cognitive…