2017 American Transplant Congress
Modulating Ischemia-Reperfusion Injuries with Pharmacological Agents: A Bench-to-Bedside Approach.
Balmes Transplantation, Marseille, France
Ischemia–reperfusion (IR) is a complex pathophysiological process encompassing activation of inflammatory responses and cell death programs, the severity of which critically influences both the short…2017 American Transplant Congress
Estrogen Receptor Alpha Mediates Female Protection from Renal Ischemia-Reperfusion Injury Through Mechanisms Extrinsic to the Kidney.
Introduction: Female protection from renal ischemia-reperfusion injury (IRI) is observed in both mouse and human renal transplantation. We wished to assess the role of estrogen…2017 American Transplant Congress
Nuclear Co-Repressor Complex Inhibition Reverses Benefit of HDAC2 Deletion in Renal Ischemia.
Introduction: Class I histone/protein deacetylases (HDACs) 1 and 2 bear >85% protein sequence homology and conventionally are thought to have similar function via occupancy in…2017 American Transplant Congress
Evaluation of Outcomes in Renal Transplantation Using Machine Perfusion for the Preservation of Kidneys from Expanded Criteria Donor.
Agence de la Biomedecine, Saint Denis La Plaine, France
Introduction:The shortage of kidney grafts led to retrieve organs from old donors with one or more co-morbidities, considered as “expanded criteria donors” (ECD). In France,…2017 American Transplant Congress
The Treatment of the Graft and the Recipient with α-Lipoic Acid Improves the Delay Graft Function Severity in the Human Kidney Transplant.
A previous pilot clinic trial had showed that treatment of the donor and recipient with a potent anti-oxidant such as α-lipoc acid (ALA) reduces the…2017 American Transplant Congress
Organs with Extended Cold Ischemia Time May Offer Aged Kidney Transplant Recipients New Options in an Expanded Donor Pool.
Using data from the largest cohort of renal transplants, the aim of this study was to examine the effects of cold ischemia times (CIT) on…2017 American Transplant Congress
Omega 3 Attenuates Ischemia Reperfusion Renal Injury via Enhancement of Autophagy Flux.
Purpose: Omega 3 fatty acid showed the protective effect against various renal injuries. Recently, it is reported that Omega 3 regulates the autophagy. Using fat-1…2016 American Transplant Congress
Role of TGF-β in Ischemia and Reperfusion Injury Induced Renal Fibrosis in Human Proximal Tubular Epithelial Cells.
Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Ischemia-reperfusion injury (IRI) leads to an irreversible damage to the tubular epithelium and promotes acute kidney injury (AKI) that is associated with progressive loss of…2016 American Transplant Congress
Cold Ischemia Induced Outcomes in Kidney Transplantation: A Meta-Analysis.
Columbia University Medical Center, New York, NY.
Objective: To examine the association between cold ischemia time (CIT) and delayed graft function (DGF) and death-censored graft failure in kidney transplantation.Methods: To identify relevant…2016 American Transplant Congress
Adopting the Kidney Donor Profile Index (KDPI)/Kidney Donor Risk Index (KDRI) for Japanese Donors After Cardiac Death.
Introduction: Due to a severe organ shortage, it is important to predict the outcome of grafts prior to kidney transplantation and establish an appropriate allocation…
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