2017 American Transplant Congress
Accumulating Mitochondrial DNA in Aging Augments Inflammatory Responses Subsequent to IRI.
Background: Older donor organs are increasingly utilized to close the gap between demand and supply. We submit that aging-associated kinetics of damage associated molecular patterns…2017 American Transplant Congress
Intravoxel Incoherent Motion MRI Is an Effective Way to Monitor Acute Allograft Rejection in Rat Models.
Urology, Chao-Yang Hospital, Beijing, China
Objectives: To combine the intravoxel incoherent motion MRI and blood oxygen level-dependent MRI for assessment of the renal allograft pathological process undergoing acute rejection and…2017 American Transplant Congress
How to Promote Regeneration After Ischemic Reperfusion Injury: Dual Role of CD 137 Agonistic Antibody.
Acute sterile inflammation can be induced by tissue damage caused by ischemia-reperfusion. In transplantation ischemia reperfusion injury (IRI) is unavoidable procedure. IRI causes delayed graft…2017 American Transplant Congress
Nafamostat Mesilate Ameliorates Ischemia-Reperfusion Renal Injury via Anti-Apoptotic Mechanism.
Purpose: It has been reported that nafamostat mesilate inhibits inflammatory injury via inhibition of complement activation in ischemic heart, liver, and intestine. However, it is…2017 American Transplant Congress
Postoperative Serum Lactate Dehydrogenase Is a "Troponin-Like" Marker of Renal Transplant Distress.
UCSD Center for Transplantation, University of California at San Diego, San Diego, CA
Lactate dehydrogenase (LDH) is plentiful in renal tubular cells and is released during tubular injury or death. It increases for several days to 1500-2000 U/L…2017 American Transplant Congress
Living Kidney Transplant: The Influence of Intraoperative Hemodynamics on Delayed Graft Function.
Despite advantages of living donor kidneys, intraoperative insults may subject these kidneys to poor outcomes. Therefore, we investigated whether intraoperative fluid volumes and hemodynamics in…2017 American Transplant Congress
Modulating Ischemia-Reperfusion Injuries with Pharmacological Agents: A Bench-to-Bedside Approach.
Balmes Transplantation, Marseille, France
Ischemia–reperfusion (IR) is a complex pathophysiological process encompassing activation of inflammatory responses and cell death programs, the severity of which critically influences both the short…2016 American Transplant Congress
Hydrogen Sulphide Is an Important Regulator of Erythropoietin Synthesis in Patients with Anemia of Chronic Kidney Disease.
Anemia affects 90% of hemodialysis patients and is a tremendous concern for patients and health care providers. CKD leads to chronic interstitial fibrosis which leads…2016 American Transplant Congress
Ischemia-Reperfusion Injury Following Transplantation: Implications for the Modulation of CXCL8 Chemokine Function.
Ischemia-Reperfusion Injury (IRI) is a major contributor to subsequent graft dysfunction. Chemokines play a key role in leukocyte recruitment towards to the injured tissue. CXCL8…2016 American Transplant Congress
Activated Cytoprotective Mechanisms in DBD Kidneys Correlate with Kidney Function in Transplant Recipients: A Study Using Clinical Samples from the UK QUOD Biobank.
The onset of abnormal pathophysiological changes following brain death adversely impact kidney function following transplantation. Understanding the biological mechanisms that affect kidney quality will allow…
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