2016 American Transplant Congress
Heparanase: A New Factor Involved in the Pro-Fibrotic Renal Biological Machinery Activated by the Ischemia/Reperfusion (I/R) Injury.
Ischemia/reperfusion (I/R) is an important cause of acute renal failure and delayed graft function, and it may induce chronic renal damage by activating epithelial to…2016 American Transplant Congress
Role of TGF-β in Ischemia and Reperfusion Injury Induced Renal Fibrosis in Human Proximal Tubular Epithelial Cells.
Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Ischemia-reperfusion injury (IRI) leads to an irreversible damage to the tubular epithelium and promotes acute kidney injury (AKI) that is associated with progressive loss of…2016 American Transplant Congress
Cold Ischemia Induced Outcomes in Kidney Transplantation: A Meta-Analysis.
Columbia University Medical Center, New York, NY.
Objective: To examine the association between cold ischemia time (CIT) and delayed graft function (DGF) and death-censored graft failure in kidney transplantation.Methods: To identify relevant…2016 American Transplant Congress
Adopting the Kidney Donor Profile Index (KDPI)/Kidney Donor Risk Index (KDRI) for Japanese Donors After Cardiac Death.
Introduction: Due to a severe organ shortage, it is important to predict the outcome of grafts prior to kidney transplantation and establish an appropriate allocation…2015 American Transplant Congress
Distinct Role of Complement Receptors C5L2 and C5aR in Acute Kidney Injury and Renal Fibrosis
ObjectiveAcute kidney injury (AKI) is a relevant complication in solid organ transplantation with incidence rates of ∼50-75 % after lung- and heart transplantation. In addition,…2015 American Transplant Congress
In Pre-Implantation Biopsies Expression of Micro RNAs Is Not a Good Surrogate for Established mRNA Markers of Kidney Injury
1University of Alberta, Edmonton, Canada; 2University of Marlyland, Baltimore.
Kidneys from brain dead donors>50 years old are often discarded based on conventional (clinical and histologic) criteria, despite their poor predictive value for subsequent performance…2015 American Transplant Congress
Anti-LG3 Antibodies Aggravate Ischemia-Reperfusion Injury
Ischemia-Reperfusion Injury (IRI) is a significant cause of renal allograft dysfunction and a risk factor for poor long-term graft outcomes. Microvascular injury is an important…2015 American Transplant Congress
Donor Serum and Urine Proteomic Signatures Differentiate Between Immediate and Delayed Graft Function in Kidney Transplantation
IntroductionDespite the persistent shortage of donor organs, paradoxically, many organs obtained from older higher risk donors are deemed unsuitable for transplantation and discarded. The ability…2015 American Transplant Congress
The Effects of Periostin on Renal Fibrosis After Ischemia-Reperfusion Injury Via p38 MAPK Pathway
Ischemia-reperfusion injury during the transplantation procedure is associated with poor long-term allograft outcomes, such as rejection and fibrosis. Periostin, a matricellular protein, has been reported…2015 American Transplant Congress
Role of Complement in Mediating Pericyte Trans-Differentiation in Resident Myofibroblasts: A New Hypothesis On Vascular Rarefaction in Renal Ischemia/Reperfusion (I/R) Injury
Vascular rarefaction is critical in the development of renal fibrosis. Pericytes regulate renal blood flow and might be an important source of renal interstitial myofibroblasts;…
American Transplant Congress abstracts