ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal function"

  • 2015 American Transplant Congress

    Pharmacist-Led Renal-Sparing Conversion to Everolimus After Liver Transplantation

    T. Horwedel,1 L. Bowman,1 W. Chapman,2 J. Hagopian.1

    1Barnes-Jewish Hospital, St. Louis, MO; 2Washington University in St. Louis, St. Louis, MO.

    Purpose: Preservation of renal function following orthotopic liver transplantation (OLT) through calcineurin inhibitor (CNI)-minimization is an established clinical objective. The use of everolimus (EVR) to…
  • 2015 American Transplant Congress

    A 52-Week, Multicenter, Prospective, Observational, Non-Interventional, Open-Label Study to Assess the Effectiveness, Safety and Tolerability of Everolimus in Kidney Transplant Patients in Taiwan

    S.-M. Wang,1 P.-C. Lee,2 J.-D. Lian,3 K.-H. Shu,4 S.-T. Wu,5 H.-C. Chen,6 C.-C. Huang,7 M.-S. Wu,8 Y.-C. Tian,9 Y.-J. Chiang,10 Y.-T. Chen,11 H.-P. Wang.12

    1National Taiwan University Hospital, Taipei, Taiwan; 2National Cheng Kung University Hospital, Tainan, Taiwan; 3Chung Shan Medical University Hospital, Taichung, Taiwan; 4Taichung Veteran's General Hospital, Taichung, Taiwan; 5TriService General Hospital, Taipei, Taiwan; 6Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; 7China Medical University Hospital, Taichung, Taiwan; 8Taipei Medical University Hospital, Taipei, Taiwan; 9ChangGung Memorial Hospital–Taipei, Taipei, Taiwan; 10ChangGung Memorial Hospital–LinKou, Taoyuan, Taiwan; 11ChangGung Memorial Hospital-Kaohsiung, Kaohsiung, Taiwan; 12E-Da Hospital, Kaohsiung, Taiwan.

    The study aimed to assess the clinical safety and tolerability of everolimus (EVR) in Taiwan kidney transplant patients.This study enrolled 203 kidney transplant recipients, between…
  • 2015 American Transplant Congress

    Improved Renal Function Post-Liver Transplant With Earlier Everolimus Conversion

    S. Lin,1 M. Zimmerman,2 V. Lewis,1 S. Biggins,3 C. Ruller,4 I. Kam,4 T. Nydam.4

    1Pharmacy Dept, University of Colorado Hospital, Aurora; 2Division of Transplant Surgery, Medical College of Wisconsin, Wisconsin; 3Division of Gastroenterology/Hepatology, University of Colorado, Aurora; 4Division of Transplant Surgery, University of Colorado, Aurora.

    Calcineurin inhibitors (CNI) play an important role in preventing acute rejection (AR) post-liver transplant. Its long-term use is limited by development of nephrotoxicity. Optimal timing…
  • 2015 American Transplant Congress

    Post Hoc Subgroup Analysis of ZEUS: Outcome on Renal Function, Efficacy and Safety in Living-Donor Kidney Transplant Recipients After Conversion from a Calcineurin Inhibitor to an Everolimus Based Regimen: 5 Year Follow-Up Data

    F. Lehner,1 K. Budde,1 R. Wuethrich,2 P. Reinke,1 W. Arns,1 A. Muehlfeld,1 U. Eisenberger,1 R. Stahl,1 K. Heller,1 O. Witzke,1 B. Suwelack,1 H. Wolters,1 I. Hauser,1 M. Porstner,3 C. Sommerer.1

    1ZEUS Study Group, Germany; 2ZEUS Study Group, Switzerland; 3Novartis, Pharma, Germany.

    Background: To study renal function and patient outcome after 5 years in living donation subgroup of kidney de novo transplant recipients after conversion to an…
  • 2015 American Transplant Congress

    Renal Allografts Demonstrate Improved Pathology After Belatacept Therapy

    T. Saavedra,1 O. Opara,1 R. McLoughlin,1 B. Philosophe,2 C. Drachenberg,1 M. Weir,1 S. Bartlett,1 D. Leeser,1 J. Bromberg,1 R. Barth.1

    1University of Maryland School of Medicine, Baltimore; 2Johns Hopkins University, Baltimore.

    Belatacept provides immunosuppression via costimulation blockade and has been associated with improved renal function compared to calcineurin inhibitor based therapies. We developed the Maryland Aggregate…
  • 2015 American Transplant Congress

    A Prospective Study of Renal Function and Histological Changes in Renal Transplant Recipients With Acute Clinical and Subclinical Rejection

    S. Chen,1 R. Mehta,1 P. Sood,1 P. Randhawa,2 N. Shah,1 C. Wu,1 A. Tevar,3 S. Hariharan.1

    1Nephrology, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA; 3Transplant Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Background: To study the impact on renal function and histological changes in patients(pts) with acute clinical rejection(ACR) and subclinical rejection(SCR) from 3 to 12 month(m)…
  • 2015 American Transplant Congress

    Utilization of Kidneys from Deceased Donors With Acute Kidney Injury

    M. Aull, S. Sultan, J. Kim, A. Watkins, D. Dadhania, S. Kapur.

    Division of Transplant Surgery, NewYork-Presbyterian/Weill Cornell Medical College, New York.

    Due to the shortage of kidneys available for transplantation and the morbidity and mortality that occurs while patients wait for a transplant, utilization of organs…
  • 2015 American Transplant Congress

    African American Race Is an Independent Risk Factor for Cytomegalovirus Infection in Renal Transplant Recipients on Low-Dose Valganciclovir Prophylaxis

    S. Patel, S. Kuten, J. Loucks-DeVos, R. Knight, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    Safe and effective use of low-dose (450 mg/day) valganciclovir (VGC) for cytomegalovirus (CMV) prophylaxis in renal transplant recipients (RTRs) has been reported. However, it is…
  • 2015 American Transplant Congress

    Renal Dysfunction After Liver Transplantation in Recipients With Pre-Transplant Normal Renal Function

    S. Lee,2 J. Lee,1 M. Kim,1 B. Kim,3 D. Joo,1 G. Choi,1 J. Choi,1 S. Kim.1

    1Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Surgery, Ajou University School of Medicine, Suwon, Republic of Korea; 3Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

    Background. Renal dysfunction is a severe complication associated with adverse outcomes after liver transplantation (LT). The aim of our study is to identify the incidence…
  • 2015 American Transplant Congress

    Safety and Outcome of Ganciclovir-Resistant CMV Treated With Foscarnet: A Single Center Retrospective Study

    B. Pierce,4 C. Richardson,4 K. Cunningham,4 C. D'Agostino,4 C. Tseng,4 J. Brown,4 C. O'Brien,4 B. Ho,1,3,5 M. Ison.1,2,3

    1Department of Medicine, Northwestern Medicine, Chicago, IL; 2Division of Infectious Diseases, Northwestern Medicine, Chicago, IL; 3Division of Organ Transplantation, Northwestern Medicine, Chicago, IL; 4Pharmacy, Northwestern Medicine, Chicago, IL; 5Transplant Nephrology, Northwestern Medicine, Chicago, IL.

    Background: Infection with cytomegalovirus (CMV) is an important cause of morbidity and mortality following solid organ transplantation (SOT). Resistance can rarely develop via mutations in…
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