2016 American Transplant Congress
Evaluation of the Long-Term Outcomes with Everolimus After Calcineurin Inhibitor Withdrawal: 36M Results of the H2304 and PROTECT Extension Studies.
Background: The H2304 and PROTECT studies demonstrated reduced nephrotoxicity with everolimus (EVR)-based calcineurin inhibitor (CNI; cyclosporine: CsA, tacrolimus: TAC)-free regimens at Month (M) 12. Here,…2016 American Transplant Congress
TRANSFORM: A Modern Approach to Evaluate Long-Term Outcomes of Everolimus with Reduced-Calcineurin Inhibitors in De Novo Kidney Transplant Recipients[mdash]Baseline Characteristics.
Purpose: Acute rejection and poor graft function are two major risk factors for allograft failure in kidney transplant (KTx) recipients (KTxR). Although, graft survival and…2016 American Transplant Congress
Impact on Renal Function of Stepwise Withdrawal of Tacrolimus Combined with Everolimus and EC-MPS vs Standard Treatment Combining Tacrolimus and EC-MPS in De Novo Liver Transplant Recipients: Results of the SIMCER Study.
Introduction: Long-term post-liver transplant (LTx) complications, particularly impaired renal function (RF) and its consequences, remain a concern. Presented here are the results of the SIMCER…2016 American Transplant Congress
The Importance of KDPI in Simultaneous Liver and Kidney Transplant.
Background: The use of the Donor Risk Index (DRI) in liver transplantation and the Kidney Donor Profile Index (KDPI) in kidney transplantation has been well…2016 American Transplant Congress
Short-Term Post-Donation Renal Function in Living Kidney Donors.
Previous single-center studies of post-donation estimated glomerular filtration rate (eGFR) in living kidney donors were limited by small sample size and lack of generalizability. The…2016 American Transplant Congress
Comparing Renal Function After Liver Transplantation: Modified Piggyback versus Conventional Techniques without Venovenous Bypass.
Surgery, Yonsei University College of Medicine, Seoul, Korea.
BackgroundThere are several options available for caval reconstruction in liver transplantation. Prior reports demonstrated that caval reconstruction technique could affect the renal function. However, there…2015 American Transplant Congress
DNA Methylation Classifier Associates With Long-Term Graft Function Post-Kidney Transplantation
1UVA, Charlottesville, VA; 2VCU, Richmond, VA; 3Noerthwestern University, Chicago, IL.
"Background. Late graft failure is a major problem after kidney transplantation (KT) mainly due to chronic renal allograft dysfunction (CRAD). Data about common pathways of…2015 American Transplant Congress
Non-Invasive Panel of MicroRNAs Predict Long-Term Outcomes Post-Kidney Transplantation
1Surgery and Pathology, UVA, Charlottesville, VA; 2VCU, Richmond, VA.
Background. Currently available methods for evaluating kidney graft function post-transplantation (KT) are either ineffective or inaccurate (e.g., serum creatinine) or highly invasive (e.g., biopsies). We…2015 American Transplant Congress
High Intra-Patient Variability in Tacrolimus Trough Blood Levels Increases the Risk of Death-Censored Graft Loss After Kidney Transplantation
Kidney graft loss rates beyond the first year showed only small improvements over past decades. Advances in maintenance immunosuppressive therapy contributed to the improvements seen…2015 American Transplant Congress
Replacement of Lamivudine By Telbivudine to Improve Renal Function for Post-Transplant Hepatitis B Patients – A Randomized Clinical Trial
Background: Lamivudine is one of the anti-hepatitis B virus (HBV) agents to prevent HBV recurrence after transplantation because lamivudine is safe for long-term use. However,…
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